Sekaf Davipharm treats cerebrovascular disorders (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Citicoline

Ingredient

Composition information	Content
Citicoline	500mg

Uses

indications

Sekaf 500mg is indicated in the following cases:

Treatment of cerebral vascular disorders (including transient strokes), Parkinson and first injury. Lecithin is one of the main components of cell membranes and the cells. Lecithin's role in cell regeneration shows that using CDPC will create pharmacological effects on the central nervous system, protect the central nervous system against many toxic substances (lack of oxygen, organic solvents with nerves ...).

There has been a correlation between brain damage and neurological disorders and phospholipid deficiency in the sick areas. The reproduction of phospholipids requires the merger of cholin into phosphatidylcholin, which is the process to be done via CDPC.

A lot of research experience has shown that while using Cholin will increase the metabolism of this substance into acetylcholin, creating cholinergic states, if using high doses CDPC does not make similar changes, even a large proportion of brain phosphatidylcholin in the sick area.

These experiments help use Sekaf to treat neurological dysfunction at advanced (dizzy, migraine, fatigue, insomnia, memory loss, decrease in physical, posture disorders and social communication dysfunction), brain damage after surgery and after brain vascular thrombosis.

pharmacokinetics

absorption:

Citicolin is soluble in water, bioavailable> 90%. In healthy adults, citicolin is quickly absorbed when used orally. The peak concentration in plasma is achieved through two stages, the first phase at 1 hour after drinking and later, greater, reaching 24 hours after drinking.

Metabolism and distribution:

citicolin is metabolized in the intestinal wall and liver. The byproduct of external hydrolysis process in the intestinal wall is Choline and cytidin. After absorption, Choline and Cytidin are distributed throughout the body, go into the circulation to participate in many different biosynthesis paths and overcome the brain blood barrier to re -synthesize the citicolin in the brain.

Era:

Histopherological research using 14C isotopes shows that citicolin is excreted mainly through respiratory and urine CO2, through 2 stages, similar to 2 stages of plasma peak concentrations. The concentration drops sharply after reaching the early stage concentration, then slowed down for the next 4 - 10 hours. The same concentration decreases after reaching the peak concentration later and then the elimination rate is slower. The sale time through the respiratory tract is 56 hours and the urine is 71 hours.

Before taking Sekaf Davipharm treats cerebrovascular disorders (2 blisters x 10 tablets)

How to use

The drug is used by oral.

Dosage

The common dose is 500 mg of citicolin/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Sekaf 500mg , you may experience unwanted effects (ADR).

Digestive: abdominal pain, diarrhea .

blood vessels: lower blood pressure, tachycardia, slow heart rate.

Instructions on how to handle ADR

The drug can cause other unwanted effects, advising patients to notify unwanted effects when taking the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Sekaf 500mg contraindicated in the following cases:

Hypersensitivity to citicolin or any ingredients of the drug.

Patient increases muscle tone of the sympathetic nervous system.

Pregnant and lactating women.

Be cautious when using

high doses of citicolin can increase brain blood flow in case of persistent intracranial hemorrhage. Do not recommend using drugs for children, to be out of reach of children.

Drugs that contain polysorbat 80 can cause allergies and castor oils that can cause nausea, vomiting, abdominal pain, diarrhea.

The ability to drive and operate machinery

There is no information on the effect of the drug on the ability to drive or operate machinery.

Pregnancy

does not have enough reliable information about safety when using citicolin for pregnant women. Do not recommend the use of drugs for this object.

The period of breastfeeding

does not have enough reliable information about safety when using citicolin for breastfeeding women. Do not recommend the use of drugs for this object.

Drug interaction

Not used with preparations containing meclophenoxat or centrofenoxin. Because the drug increases the effectiveness of Levodopa, it is necessary to be cautious when combining these 2 drugs.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Dat Vi Phu Pharmaceutical Co., Ltd is one of the leading high quality original drug manufacturers in the country. Founded in 2004, certified by the WHO-GMP in 2006, Davipharm reached the first 100 products registered and started exporting drug products to the Philippines and Cambodia. Since 2016, in the top 5 pharmaceutical companies in the country.

In 2017, Adamed Pharma S.A. Buy back the dominant contribution of Davipharm to upgrade the production standards and implement EU-GMP (expected in early 2021), technology transfer and export development. Davipharm's goal is to consolidate its position in the domestic market, leading the research and development, launching new products, producing contracts and forming the Southeast Asian Export Center.

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