SeoSacin Theragen Etex Smor treatment for bronchial asthma, acute or chronic bronchitis (30 packs x 10ml)
Dosage form Box of 30 packs x 10ml
Specifications Ambroxol, clenbuterol
Ingredient
| Composition information | Content |
| Ambroxol | 15mg |
| Clenbuterol | 0.01mg |
Uses
Indications
Syrup Seosacin is used to treat bronchial asthma, acute or chronic bronchitis, emphysema.
Pharmacology
Pharmacological group: Drugs used to treat eye, ear, nose and throat
ATC code: R03CC P1
The drug is a combination of receptor stimulants B2 - adrenergic selective (clenbuterol) and mucus (ambroxol). These two components complement each other's treatment effects on respiratory diseases. Clenbuterol causes bronchospasm and increases the transportation of mucus thanks to the respiratory hair hairs. Ambroxol is considered to have a long sputum and mucus. The synergistic effect of both active ingredients helps improve ventilation for patients with mild and moderate pulmonary obstruction.
Clenbuterol HCI
Clenbuterol is a sympathetic drug that stimulates the receptor of B2 - Adrenergic receptor that will increase the activity of Adenylyl Cyclase, leading to an increase in the amount of amp, loop Amp reduces bronchodilator muscle, stabilize the mast cell membrane should reduce intermediate secretions and stimulate muscle patterns (causing tremor), increase the transport of mucus by respiratory hairs.
Ambroxol HCI
Ambroxol is a metabolic substance of bromhexin, which works and uses like bromhexin.
It is different from Bromhexin is the absence of a methyl group and instead is the hydroxyl group in the Para-Trans position of Cyclohexyl. Ambroxol is considered to have a long sputum and mucus but not fully proven. Clinically experimental experiments give changing effects. Some documents stated Ambroxol improving symptoms and reducing the number of acute batches in bronchitis.
The recent documents show that the drug has a good effect on patients with mild and medium obstruction, but there is no clear benefit for people with severe obstructive pulmonary disease.pharmacokinetics
ambroxol
Absorption: Ambroxol absorbs fast and almost completely with the dose of treatment.
Distribution: Ambroxol diffuses rapid from blood to tissue with the highest drug concentration in the lungs. Birth is about 80%. The maximum concentration in plasma is achieved within 1-3 hours after taking the drug. With the treatment dose, the drug is linked to plasma protein approximately 85% (80% - 90%). The drug is through cerebrospinal fluid, placenta and breast milk.
Metabolism: Ambroxol is metabolized mainly in the liver.
Elimination: Half a lifetime in plasma from 7 to 12 hours. About 30% of oral dose is discharged through the first absorption ring. The total amount of excretion through the kidney is approximately 90%.
Severe liver failure:
In severe liver disease, Ambroxol's disposal time decreased by 20 - 40%.
Severe kidney failure:
The semi -exhaust time of ambroxol metabolites lasts longer.
clenbuterol:
absorption: Clenbuterol absorbs quickly and completely through the gastrointestinal tract. The sale time is about 60 minutes. After the first dose, the maximum plasma concentration is achieved after 120 - 180 minutes. After 4 days of treatment, the drug reaches a stable plasma concentration.
Distribution: Birth is about 100%. Drugs through placenta.
Elimination: The drug excreted through 2 stages, the half -life period of except for about 60 minutes and half -life eliminated slowly about 34 hours. The sale time of drugs from 36 - 39 hours.
The drug is excreted mainly in urine in the form of unchanged.
Before taking SeoSacin Theragen Etex Smor treatment for bronchial asthma, acute or chronic bronchitis (30 packs x 10ml)
How to use
Syrup Seosacin oral.
Dosage
recommended dose:
do when using overdose? If an overdose occurs, medication should be stopped and symptomatic treatment.
In an emergency, call the 115 emergency center immediately or go to the nearest local health station.
What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
When using the drug, there are common unwanted effects (ADR) such as:
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Syrup Seosacin contraindicated in the following cases:
Be cautious when using
need to be very careful when taking the drug for patients in the following cases:
Use drugs for women during pregnancy and lactation
Pregnancy
There is no document to prove safety when taking the drug during pregnancy. Therefore, be cautious for pregnant women, especially in the first 3 months of pregnancy.
Breastfeeding period
There is no information about the concentration of the drug in breast milk.
affects the ability to drive and operate machinery
The drug can cause headaches, dizziness affecting the ability to drive and operate machinery. Therefore, it is necessary to be cautious for those who have to do these jobs.
Drug interaction
Do not take drugs with antibiotics (amoxycilin, cefuroxim, erythromycin, doxycyclin) because ambroxol increases antibiotic concentration in lung parenchyma.
Do not use medication with enzyme inhibitors.
Storage
Leave a cool place, avoid light, temperature below 30⁰C.
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