Setbozi Stick solution reduces the symptoms of sneezing, runny nose (20 tubes x 5ml)

Dosage form Oral solution
Specifications Box of 4 blisters x 5 tubes
Ingredient Desloratadine

Ingredient

Thành phần cho 5ml

Composition information	Content
Desloratadine	2.5mg

Uses

indications

Setbozi stick appointed treatment in the following cases:

Used to reduce the symptoms of allergic rhinitis (seasonal and chronic) such as sneezing, nose and itchy nose, stuffy nose, with eye irritation, watery eyes and red eyes. H.

Code ATC: R06AX27

Desloratadin is a loratadin -active metabolic substance, which has a selective antagonistic effect with Histamine H, peripheral receptors. The effect of desloratadine due to inhibits the cohesion of histamine in the cycle of the receptor position. The drug does not prevent the release of histamine. Desloratadin inhibits the smooth muscle contraction of the respiratory system, circulatory system, digestive system, reducing the secretion of active histamine from the salivary glands and salivary glands and thus has anti -inflammatory effects. The drug also reduces capillaries should reduce itching and allergic inflammation.

Because the desloratadin does not pass through the brain blood barrier and has a selective effect on peripheral histamines, the sedative and sympathetic effect of the desloratadine is very low.

Dynamic pharmacokinetics

Can find desloratadine concentrations in plasma after taking the drug for 30 minutes.

Desloratadin is very good absorption, reaching the peak concentration in plasma after about 3 hours, the final waste time is about 27 hours.

Desloratadin accumulation is suitable for the sale time (about 27 hours) and with a single -dose frequency of the day.

The bioavailability of desloratadin is proportional to the dose in the range of 5 - 20 mg. Desloratadin moderately attached to plasma proteins (83 - 87%).

Clinically

clinically, not yet found to accumulate drugs after taking the only dose of 5 - 20 mg daily, lasting 14 days.

Before taking Setbozi Stick solution reduces the symptoms of sneezing, runny nose (20 tubes x 5ml)

How to use

Setbozi Stick The oral solution.

Food does not affect the bioavailability of the drug, so the patient can take the drug without depending on the meal.

Dosage

recommended dose:

Children from 6 - 11 years old: 2.5 mg/time x 1 time/day.

Adults and children over 12 years: 5 mg/time x 1 time/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

When an overdose is overdose, it is necessary to take standard measures to withdraw the active ingredient that has not been absorbed from the body. Symptomatic and supportive treatment must also be taken.

No desloratadine is not discharged by dialysis, it is unclear whether it is excreted by the abdominal separation.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Setbozi Stick often has unwanted effects (ADR).

Very common, ADR> 10/100:

Headache.

Common, 1/100

tired, sleeping, dizziness.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Setbozi stick is contraindicated in the following cases:

Patients with Desloratadin sensitive patients and with any ingredients of the drug.

Be cautious when used

Overdose and toxicity (including death) have been reported in children under 2 years of age using non -prescribing preparations containing antihistamine drugs, reducing cough, sputum and anti -nasal congestion to reduce symptoms of the upper respiratory tract. There is no evidence that the clear effect of these preparations is under 2 years old and the appropriate dose has not been published.

Therefore, be careful when using non -prescription drugs (merely or coordinated) contains antihistamine drugs, reduces cough, sputum and anti -nasal congestion to reduce them, reduce flu symptoms for children under 2 years old.

Despite the rare sleep of chickens in second -generation antihistamines than the first generation, but may appear in some patients, so they must be cautious for drivers or operating machines. Drinking alcohol should also avoid while taking the drug.

Sometimes there are reports on seizures that appear in patients with antihistamine drugs, so they also need to be cautious when taking desloratadine for patients with epilepsy.

Desloratadin eliminates the kidneys in the form of metabolites that are active, so it should be noted to reduce the dose in patients with renal impairment. Similarly, descending dose of desloratadine in patients with liver failure.

The effect when operating machinery and driving train

desloratadin usually does not cause drowsiness when used with recommended dose and under normal conditions. However, it is very rare for some people to feel dizzy and drowsy can lead to decline in driving and operating machinery. Therefore, be careful when using drugs for operators and train drivers.

Pregnant women and breastfeeding women

Pregnancy: Although animal studies show that desloratadin does not cause teratogenicity, should also be cautious when using desloratadin for pregnant women.

Demon: Desloratadin through breast milk, so decide to stop breastfeeding or stop taking the drug after considering the importance of the drug for the mother.

Drug interaction

Medicines that affect liver enzymes: Pharmacy interactions may occur (increasing the concentration of desloratadin and active metabolites) when using desloratadine simultaneously with drugs affecting liver enzymes (such as azithromycin, cimetidine, erythromycin, fluoxetin, ketoconazole).

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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