Shinpoong Daewoo Distocide Shinpoong Treatment Treatment, Small Liver Tapeworm (1 blister x 4 tablets)

Dosage form Box of 1 blister x 4 tablets
Specifications Prazancelel
Ingredient Infection with tapeworms, Tapphs infection

Ingredient

Composition information	Content
Prazancelel	600mg

Uses

indications

Distocide 600 mg is indicated in the following cases:

Treatment of schedule;

Small liver tapeworm; There is a wide spectrum against liver tapeworm, schedule and many types of tapeworms.

Praziquantel Treatment of all kinds of diseases for humans, small liver fluke clonorchis sinensis, Opisthorchis viverrini, Fasciola hepatica, Paragonimus Westermani pulmonary, P. Uterobilateralis, P. Kellicotti, and Metagonimus Yokogawai, Nanophyetus Salminalcoles, FASCILOPSIS BUTKOTUTUS Heterophyes heterophyes.

Prazancelel works against adult tapeworms, adults and larvae stage for humans, including diphyllobothrium latum (tapeworm), dipyridium caninum (cat tapeworm, cat fluid), Hypenolepis nana (dwarf fluid), tenia saginata (tapeworm), T. Solium (Slug of Pork), cysticcus cellsae pig).

The mechanism of acting of Praziquantel related to the synonym between the drug and the immune response of the host of S. Mansoni. Praziquantel is quickly absorbed and increased the permeability of flukes, leading to the loss of intracellular calcium, spasticity and muscle paralysis of the flukes quickly.

When exposed to Praziquantel, the skin of the mature neck of the neck appears blisters, then they are broken and decomposed.

Prazancelel also causes strong non -celly in many places on the skin of the mature Schistosoma scheme. This, in Slap S. Mansoni, leads to parasitic phytsty phenomenon and eventually kills parasites.

Dynamic pharmacokinetics

in San:

Prazancelel is quickly absorbed by schistosons and other types of flukes.

In humans:

The drug is absorbed quickly when taken, even when taken at meals, over 80% of the dose is absorbed, reaching the peak concentration after drinking from 1-3 hours, attached to plasma proteins is 80 - 85%.

The drug is distributed in the entire fluke body. In humans, the concentration of drugs in cerebrospinal fluid is 15-20% of plasma concentrations.

The semi -discharged time from Prazancelel's plasma is 1 - 1.5 hours and of metabolites is 4 hours. The drug excreted in the urine mainly in the form of metabolites, about 80% of the dose is eliminated within 4 days and more than 90% of these excreted in the first 24 hours. Medicines in breast milk.

Before taking Shinpoong Daewoo Distocide Shinpoong Treatment Treatment, Small Liver Tapeworm (1 blister x 4 tablets)

How to use

Praziquantel usually drink during meals. The drug is not chewed but can be broken into 2 or 4 to use each separate dose.

To reduce the risk of side effects on the nervous system, it is possible to use Prazancelel combination with dexamethasone 6 - 24 mg/day or Prednisolone 30 - 60 mg/day in patients with tapeworm larvae in the brain.

Dosage

Talme:

The dose is commonly used for adults and children over 4 years old is 60 mg/kg, divided 3 times with a distance of 4-6 hours (the dose may be 40 mg/kg, divided 2 times, in some patients).

Small liver fluke clonorchis sinensis and Opisthorchis vietrini:

The common dosage for adults and children is 75 mg/kg/day, divided 3 times (may be 40 - 50 mg/kg/day, oral 1 time).

Fascosiside Buski, Heterophyes Heterophyes, Metagonimus Yokogawai:

Use 75 mg/kg/day, divide 3 times for both adults and children.

nanophyetus salincona:

Use 60 mg/kg/day, divide 3 times a day for both adults and children.

fasciola hepatica:

Use 25 mg/kg/day, 3 times a day, use 5-8 days.

p. Westermani:

Use 25 mg/kg/time, 3 times a day, use 1-2 days, for both adults and children.

tapeworms in adulthood and in the intestine; Fish fluke, cow flukes, tapeworms, tapeworms:

Use 5 - 10 mg/kg, use a single dose for both adults and children.

Hymenolepis Nana:

Use 25 mg/kg/time, use a single dose, for both adults and children.

Larval and tissue phase:

Treatment of larval phase of tapeworm 50 mg/kg/day, divided into 3 times, use 15 days.

For tapeworm larvae in the brain:

50 mg/kg/day, divided equally 3 times, in 14-15 days (can be up to 21 days for a few patients).

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? Use laxative effect quickly when drinking Praziquantel overdose.

What to do when forgetting a dose?

Side Effects

When using 600 mg Distocide, you may experience unwanted effects (ADR). Common side effects but usually light and fast.

Common, ADR> 1/100

Systemic: Fever, headache, discomfort.

Neurological: dizziness, drowsiness.

Digestive: abdominal pain or abdominal spasms, poor appetite, nausea, vomiting, diarrhea and blood.

Uncommon, 1/1000

Skin: rash, itching.

Rare, ADR

Liver: Increase liver enzyme.

skin: urticaria.

Instructions on how to handle ADR

When encountering side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Distocide 600 mg contraindicated in the following cases:

Hypersensitivity to the drug.

Slap rice disease in the eyes.

Rice of the spinal fluid.

Be cautious when using

without driving, control machines while taking the drug and for 24 hours after taking Praziquantel because the drug can cause dizziness and drowsiness.

Caution for patients with a history of convulsions.

The ability to drive and operate machinery

No driving, control machinery while taking the medicine and even 24 hours after taking Praziquantel because the drug can cause dizziness, drowsiness.

Pregnancy

The research has not been conducted in humans. However, Praziquantel can cause a miscarriage in a mouse with a dose of 3 times the dose for humans. Therefore, the drug is not used for pregnant people.

breastfeeding period

praziquantel to breast milk. The mother has to stop breastfeeding during medication and 72 hours after the last dose. During this time, milk must be squeezed and removed.

Drug interaction

Carbamazepine or Phenytoin can significantly reduce prazientel levels in plasma plasma caused by carbamazepine and phenytoin touch enzyme system cytochrome P450 in microsom.

Storage

In closed packaging, in a dry place, avoid light, temperature below 30 ° C.

Stay out of reach of children.

About Shinpoong Daewoo Pharmaceutical Co., Ltd:

10/1996, establishing a company. 9/2000, completed the factory construction. 5/2003, receiving GMP certificates for pills, capsules, ointments. 10/2003, GMP certificates for powder injection lines and GLP certificates. 12/2003, becoming a 100% foreign capital company.

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