Silverzinc 50 OPV's TTTH TAO Prevent and treat zinc deficiency (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Zinc

Ingredient

Composition information	Content
Zinc	50mg

Uses

indicated

Silverzinc 50 used as supplements to prevent and treat zinc deficiency, for example in malabsorption syndrome, in case the body is lost (trauma, burns, protein loss), colds, diarrhea and during pregnancy. Li: Zinc supplement. ATC code: A12cb02

Zinc is an essential nutritional ingredient present in many foods. Zinc is a component of many enzymes and is present in all tissues. Characteristics of zinc deficiency include developmental retardation and defects in tissues quickly divided such as leather, immune system, and intestinal mucosa. Water -soluble zinc salts are used as supplements to adjust zinc deficiency, for example, in malabsorption syndrome, throughout the stage of cultivation by intravenously, or cases of the body increases zinc loss (such as trauma, burns and protein loss) and Acrodermatitis Enteropathica (a rare genetic disorder characterized by heavy zinc shortage). Zinc has been tested in the treatment of many conditions that may be related to zinc deficiency such as colds, diarrhea, or supplements during pregnancy.

pharmacokinetics

The absorption of zinc through the gastrointestinal tract is incomplete and reduced if there is a presence of some nutritional components such as phytat. The bioavailability of zinc in diets varies and is about 20-30%. Zinc is distributed throughout the body with the highest concentration found in muscles, bones, skin, eyes and prostate fluids. Zinc is mainly excreted in feces. A small amount through urine and sweat.

Before taking Silverzinc 50 OPV's TTTH TAO Prevent and treat zinc deficiency (10 blisters x 10 tablets)

How to use

Take it with meals.

Dosage

Zinc deficiency:

Normally: Adults and children over 30kg: 1 tablet, 1-3 times/day.

Children 10 - 30kg: ½ capsule, 1-3 times/day.

Children under 10kg: ½ capsule/day.

Children> 6 months old with diarrhea: 20 mg/day, for 10-14 days.

Children from 1 to 6 years old: 25mg 2 times daily.

Children from 6 to 16 years old and weighs below 57kg: 25mg 3 times daily.

Adolescents from 16 or weighing over 57kg: 50mg 3 times daily.

Effective dose in pregnant women: 25mg 3 times daily. However, the dose is adjusted based on copper concentration.

What to do when overdose? All of these patients also have a shortage of copper despite having a copper addition in a case.

How to handle: In case of acute overdose, zinc salts are corrosive due to the formation of zinc chloride by gastric acid. Treatment includes drinking milk or alkaline carbonate or activated carbonate. The use of medications should be avoided.

What to do when forgetting a dose?

Side Effects

Common, 1/100 Digestive: stomach irritation. Other: increased amylase, lipase and alkaline phosphatase in the blood.

less common, 1/1000 Blood and lymphatic system: iron -cell anemia, leukemia. Anemia may be large, small or normal red blood cells and are often associated with leukemia. Checking the bone marrow often shows the characteristic "Red blood cells" (developing red blood cells containing iron molecules forming a typical circle surrounding the nucleus). They can be early manifestations of copper deficiency and can recover quickly after reducing zinc dose. However, they must be distinguished from hemolytic anemia that often occurs in serum, where high freedom of uncontrolled freelance in Wilson's disease.

The most unwanted effects are stomach irritation. This is usually worst with the first dose in the morning and disappears after the first days of treatment. Using the first dose in the middle of the morning or serving with meals can often reduce symptoms. Alkaline phosphatase, amylase and lipase phosphate in serum can occur after a few weeks of treatment, with concentrations often returning to normal within one or two years of treatment.

Notice immediately to the doctor or pharmacist the harmful reactions encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hypersensitivity to zinc gluconate or any ingredient of the drug.

Be cautious when used

long -term use with high doses of zinc supplements leads to copper deficiency and siderloblastic anemia and neutropenia. Blood formula and cholesterol should be monitored to detect signs of copper shortage early.

The effect of the drug on the ability to drive and operate machinery

has not recorded a report on adverse reactions or no research on the effect of the drug on the ability to operate machinery, train drivers, people working on high and other cases.

Use drugs for women during pregnancy and lactation

Use drugs for pregnant women:

Data is limited in the use of drugs during pregnancy in patients with Wilson's disease, showing that there is no zinc's effect on embryos/fetal and mother. Five cases of miscarriage and two birth defects (small heads and heart defects can be cured) have been reported in 42 cases of pregnancy.

Animal research is conducted with various zinc salts that do not show direct or indirect effects related to pregnancy, embryo/fetal development, childbirth or development after birth. It is very important that Wilson patients who are pregnant should continue treatment during pregnancy. The treatment of zinc or chelate agents should be decided by the doctors. The dose adjustment should be adjusted to ensure that the fetus will not become lacking and mandatory closely monitor patients.

Use drugs for breastfeeding women:

Zinc is excreted in breast milk and zinc can cause a shortage of copper in breastfed babies. Therefore, breastfeeding should be avoided when treated with zinc.

Interactive drug

Drug interaction: The absorption of zinc can be reduced by iron supplements, penicilamine, compounds containing phosphorus and tetracyclin.

Zinc supplements reduce copper absorption, fluoroquinolon, iron, penicilamine, and tetracyclin.

Cavalry: Not applicable.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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