Silvirin Raptakos cream prevention and treatment of infections in the second, three (20g) burns

Dosage form Cream
Specifications Tube
Ingredient Silfadiazine Silver U.S.P
Indication Skin burns, sunburns

Ingredient

Composition informationContent
Silfadiazine Silver USP1.0% TL/TL

Uses

Indications

Preventing and treating infections in an interview with degree 2 and level 3, tearing, scratches and wounds.

Pharmacological

Silfadiazin silver only acts on the cell wall to create the antiseptic effect of the drug. Silver is gradually released from preparations at a selective concentration for bacteria. Both components in the complex are active. The drug may have special value in the treatment of children.

Silfadiazin silver is effective on a variety of gram -positive bacteria and gram sounds and effective antigen. Silver Sulfadiazin inhibits other antibacterial antibacterial bacteria and is better sulfadiazin . Silver Sulfadiazin has been shown to be effective for the following bacteria:

pseudomonas species:

pseudomonas aeruginosa

pseudomonas cepacia

pseudomonas maltophilia.

Enerobacter Species:

Enerobacter aerogenes

Enerobacter Agglomerans

Enerobacter Clacae.

Herellea Species.

klebsiella species

klebsiella pneumoniae.

Escherichia coli.

Serratia Species:

Serratia Liquifaciens

Serratia Marcescens

Serratia Rubidae.

Proteus Mirabilis

Proteus Morganii

Proteus Rettgeri

proteus vulgaris.

Providencia Species:

citrobacter diversus

Shigella Species

Acinetobacter Anitratum

aeromonas hydrophilia

Arizona Hinshawii

Alcaligenes Faecalis

Staphylococcus aureus

Staphylococcus epidermidis

β-hemolytic staphylococcus

strepticoccus group d

(including Enterococcus)

Bacillus Species

candida albicans

corynebacterium diphtheriae

Clostridium perfringens.

Sulfadiazin is absorbed about 10 %, while silver is only absorbed about 1 %. Serum concentration is about 10 - 20 mcg/ml when applied on a large scale.

Distribution:

No report.

Metabolism:

No report.

Era:

No report.

Before taking Silvirin Raptakos cream prevention and treatment of infections in the second, three (20g) burns

How to use

Apply medicine by hand with aseptic gloves, apply 1 or 2 times/day a day of about 1.5 mm thick on the wound was washed and cut necrotic tissue. The burning area is always covered with silver sulfadiazin. When necessary, apply the drug cream in any place that is drifted by the patient's activity. There is no need to tape but maybe the wound if the patient needs.

Bathing: If possible, bathe the patient every day to help remove necrotic tissue.

Dosage

Use 1-2 times/day.

Apply more cream if the drug is washed away by the patient's activity.

Treatment time: Continue treatment until healing or until the burning area is ready to get a skin transplant. Do not stop the drug when the risk of infection remains, unless it appears adverse effects.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

Skin: burning sensation.

Uncommon, 1/1000

Skin: rash, itch .

urinary tract: interstitial nephritis .

Unknown frequency

Hematology: leukopenia.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

  • Pregnant or near birth.
  • Premature babies under 2 months of age.

    • Sensitive to silver or sulfonamid.

    Be cautious when using

    It is unclear whether the drug is cross -sensitive with other sulfonamides, if the allergic reaction occurs, it is necessary to stop using the drug.

    Patients with glucose-6-phosphate dehydrogenase deficiency may be hemolysis when taking Silvirin.

    Cuong fungus inside and under the scales can appear at the same time with the decline in bacteria. However, rarely develop into a fungal disease.

    Serum sulfonamide concentration in the treatment of burns is too wide: serum sulfonamide concentration can reach adult treatment concentration (8-12 mg%). Therefore, it is necessary to regularly monitor kidney function and check the sulfadiazin crystal in urine.

    If the renal or liver function is impaired, it can reduce the ability to eliminate and increase the accumulation of drugs. It is necessary to consider stopping the drug with the benefits of treatment. Do not use overdue drugs stated on the label.

    The ability to drive and operate machinery

    Silvirin does not affect the ability to drive and operate machinery.

    Pregnancy

    Safety in pregnant women has not been proven. Do not recommend for women who are pregnant unless the burn is more than 20% of the total skin surface area or benefits that bring greater risks to the fetus.

    The period of breastfeeding

    It is unclear whether silver sulfadiazin is excreted in breast milk or not. However, all sulfonamid derivatives may increase the risk of brain -skinned jaundice for children, so be careful when prescribing for breastfeeding women.

    Interactive drug

    Silver can be inactivated in the enzyme applied on the spot when used simultaneously.

    Storage

    Store at temperatures not more than 30 ° C, dry place, avoid light.

    Other drugs

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