Silygamma 150mg Worwag treatment for chronic hepatitis, cirrhosis (4 blisters x 25 tablets)
Dosage form Tablet
Specifications Box of 4 blisters x 25 tablets
Ingredient Silymarin
Indication Cirrhosis, chronic hepatitis
Contraindication Drug allergy
Ingredient
| Composition information | Content |
| Silymarin | 150mg |
Uses
Indications
Silygamma drug is indicated in the following cases:
In short, as a result, the cell membrane is stable and the phenomenon of losing the soluble products of liver cells (such as transaminase enzymes) will be inhibited and prevented.
Silygamma will inhibit liver toxic substances (such as cellular toxins) as soon as these substances enter the cell.
Silygamma increases the synthesis of protein based on the activity of RNA polymerase-l right in the cell nucleus leading to an increase in the formation of ribosome RNA. Therefore, the synthesis of structural protein molecules and enzymes (enzymes) is increased. In short, the ability to recover and regenerate the liver is increased.
Dynamic pharmacology
Silygamma is a mixture of syribinins, sylidianin, sylichristin and some other flavonol derivatives extracted from hemp.
After absorbing through the gastrointestinal tract, the main ingredient of silymarin is the siiBinin eliminated up to more than 80% in the bile in the form of sulphate and glucoronide complex. About 10% of the dose of use goes into the hepatic circulatory round, so the maximum content in the blood is relatively low.
Sell waste time is 6.3 hours. There is no accumulation of syriinin. Silibinin excretion reaches equilibrium when the dose is repeated at the latest on the 2nd day.
Before taking Silygamma 150mg Worwag treatment for chronic hepatitis, cirrhosis (4 blisters x 25 tablets)
How to use
Silygamma 150mg drug used orally, can be used when hungry or full.
Dosage
Adults and teenagers aged 12 years and older: 1 capsule, 2 times a day, drink with sufficient amount of water (about 1 cup) before or during meals unless otherwise specified.
The doctor decides the treatment time.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when using overdose? The undesirable reactions described above may occur with more severe levels. If there is suspicion of overdose, please contact the doctor.
What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
When using SilyGamma you can experience unwanted effects (ADR).
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Silygamma drugs are contraindicated in cases where there is a history of sensitivity to the milk thistle or with the plants of the chrysanthemum family or with any ingredients of the drug.
Caution when used
This drug contains lactose, so patients with galactose intolerance due to rare genetics, lactase deficiency or glucose-galactose should not be used in SilyGamma. In parallel with the drug treatment must be away from the causes of liver damage (alcohol).
Must notify the doctor cases of jaundice (the skin color change from light yellow to dark, white eyes are yellow).
There are no adequate studies in children. Therefore SilyGamma is not used for children younger than 12 years old.
The ability to drive and operate machinery
No.
Pregnancy
Do not use silygamma for pregnant women.
Breastfeeding period
Do not use silygamma for breastfeeding women due to lack of appropriate studies.
Drug interaction
Silymarin reduces the activity of the enzyme CYP3A4 in vitro.
If using Silymarin along with the metabolic drugs by the CYP3A4 enzyme, it may change the pharmacokinetics of those drugs.
The influence of other isenzymes in the cytochrome P450 enzyme system must also be considered.
Silical studies on Silygamma have not been reported. However, it should be monitored when using SilyGamma simultaneously with drugs with the above characteristics.
Storage
Store at temperatures below 30 ° C, in the original packaging and avoid light.
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