Simegaz Plus OPV peppermint drink, treat stomach ulcers, increase gastric acid (20 packs x 10ml)

ATC code: A02AF02.

aluminum hydroxyd is an inorganic salt used as an antacids. The drug reacts with excess hydrochlorid acid in the stomach, so it reduces symptoms of peptic ulcer, heartburn, heartburn or bloating, gastroesophageal reflux.

Magnesi salts are used as an anti -acidic, laxative and magnesium anti -acid drugs when the body is lacking. Because the solubility of the magnesi hydroxyd is low, all the amounts of magnesi hydroxyd are dissolved in water. Due to this completely separation, Magnesi Hydroxyd is considered a strong alkaline. Magnesi Hydroxyd is slowly absorbed, so the effect of neutralizing prolonged gastric acid.

Simethicon reduces surface tension and reduces the fullness of air tension caused by linking air bubbles in the digestive tract, thus reducing bloating.

Dynamic pharmacokinetics

When taken, aluminum hydroxyd reacts slowly with stomach hydrochloride acid to form soluble aluminum chlorid, a small number is absorbed into the body.

Food in the stomach makes the drug from the stomach slower when there is no food, so it extends the reaction of aluminum hydroxyd with the stomach hydrochloride acid and increases the amount of aluminum chlorid. About 17 - 30% of chlorid aluminum forms absorbed and eliminated very quickly through the kidneys with normal kidney function. In the Chloride aluminum small intestine, it is quickly transformed into insoluble, absorbent aluminum salts, which can be a hydroxyd aluminum mixture, oxyaluminum hydroxyd, aluminum aluminum aluminum and aluminum soap. Hydroxyd aluminum also coordinates with phosphate in food in the small intestine to form insoluble phosphate aluminum, not absorbed and eliminated into the feces.

Absorbed aluminum is excreted through urine. Therefore, patients with renal failure are at risk of aluminum accumulation (especially in bones, central nervous systems) and aluminum poisoning. Aluminum absorbing will be attached to serum protein, difficult to remove by fertilizer.

Magnesi Hydroxyd, the drug starts to work as soon as hungry, the drug lasts for about 30 ± 10 minutes. If drinking at meals, or within 1 hour after eating, the effect lasts for about 1-3 hours. About 30% Magnesi is absorbed. Magnesi is less soluble in water, poorly absorbed compared to sodium bicarbonate, so it is not afraid to cause alkaline infection.

Due to changing gastric and urine pH, anti -acid drugs can change the speed of solubility and absorption, bioavailability and renal elimination of some drugs; Magnesi salt also tends to adsorb drugs and create an insoluble complex so it is not absorbed into the body.

Magnesi is eliminated through the kidneys when the kidney function is normal. The part is not absorbed through feces.

Simethicon is a physiological inert; It does not seem to be absorbed through the gastrointestinal tract or obstructing gastric secretion or nutrient absorption. After oral, this drug is excreted in the form of unchanged.

What to do when overdose?

Large doses can cause or worsen intestinal obstruction and intestinal obstruction in patients at risk.

Management: Aluminum and Magnesi are eliminated in the urinary tract, acute overdose treatment including calcium gluconate intravenous injection, water compensation and forced diuretic. In the case of impaired renal function, dialysis or peritoneal jurisdiction is necessary.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

The effect of the drug on the ability to drive and operate machinery

has not seen a report on affecting the ability to drive and operate machinery.

Using drugs for women during pregnancy and lactation

The safety of the drug has not been set.

Due to limited absorption, when used as recommended, the minimum amount of aluminum hydroxyd and Magnesi salt combined is still likely to be excreted into breast milk.

Simethicon is not absorbed through the gastrointestinal tract.

There is no effect on newborn/infant babies because of the systemic exposure of nursing women with aluminum hydroxyd, magnesi hydroxyd and simethicon are negligible.

Medicinal interaction

aluminum hydroxyd, magnesium hydroxyd can change the absorption of the drugs. Drink simultaneously with tetracyclin, digoxin, indomethacin, iron salt, isoniazid, alopurinol, benzodiazepin, corticosteroids, penicilamin, phenothiazin, ranitidine, ketoconazole, otraconazole can reduce the absorption of these drugs. Therefore, it is necessary to take these drugs away from antacids.

Magnesi Hydroxyd increases the effects of drugs: Amphetamine, quinidine (because they are reduced excretion).

levothyroxin can link to Simethicon. The absorption of levothyroxin may be reduced if the drug is taken simultaneously to treat thyroid disorders in children.

Cavalry: Not applicable.