Siro Duphalac Abbott for constipation (200ml)

Dosage form Solution
Specifications Bottle x 200ml
Ingredient Lactulose
Indication Constipation, liver brain
Contraindication Ulcerative colitis, abdominal pain

Ingredient

Thành phần cho 15ml

Composition informationContent
Lactulose10g

Uses

Indications

Duphalac Syrup Abbott 200ml is indicated in the following cases:

  • Constipation treatment: The physiological peristalsis of the colon. penetration.

    In Lactulose colon is decomposed by bacteria in the colon into low molecular organic acids. These acids reduce the pH in the colon and thanks to the osmotic effect that leads to the volume of substances contained in the colon. These effects stimulate the peristalsis of the colon and restore the normal firmness of the feces. Constipation is corrected and the physiological rhythm of the colon is re -established.

    In the liver brain disease, this effect is attributed to the blocking of protein hydrolyzed bacteria by increasing acid -preferred bacteria (eg lactobacillus), retaining ammonia in the form of ion by acidifying substances contained in the colon, low pH in the colon as well as due to penetrating effects, and changing the nitrogen metabolism of bacteria using bacteria to synthesize protein bacteria to synthesize protein protein of the protein bacteria.

    However, in this case, it has been realized that increased ammonia increases can not explain the nervous-spiritual manifestations of the liver brain disease. However, ammonia can be considered as a sample for other nitrogen containing substances.

    Lactulose is a microbiological substance that increases the growth of beneficial bacteria such as Bifidobacterium and Lactobacillus, while potential diseases like Clostridium and Escherichia Coli may be blocked.

    This leads to favorable balance for intestinal bacteria.

    Dynamic pharmacokinetics

    lactulose are slowly absorbed after drinking and to the colon in a constant form. There it is transformed by the bacteria in the colon.

    Completely metabolized at doses from 25 - 50 g or 40 - 75 ml; At higher doses, partly can be eliminated in a constant form.

  • Before taking Siro Duphalac Abbott for constipation (200ml)

    How to use

    can use diluted or non -diluted Duphalac oral solution.

    Single dose of the drug should be used once and should not be kept in the mouth for a long time.

    Dosage should be adjusted to respond to the drug for each patient.

    In case of taking 1 daily order, drink at the same time of the day, for example drinking in the morning.

    During the treatment with laxatives, drinking enough water per day (1.5 - 2 liters, equivalent to 6-8 cups of water).

    For duphalac bottle form can use the attached cup to dose.

    For Duphalac package 15 ml, tear a part of the package and use the drug.

    Dosage

    used in constipation or when making soft stools is considered to be beneficial for treatment:

    Can take a daily dose or divided into 2 doses, for duphalac bottled form, can be used to measure to do the dose.

    Based on the treatment response, adjust the starting dose to the maintenance dose after a few days. It takes a few days (2-3) days of treatment to be able to see the effectiveness of treatment.

    bottled duphalac oral oral solution. Age) 15ml, corresponding to 1 pack 10 - 15ml, corresponding to 1 pack* 5ml

    Should use duphalac bottled when you need an accurate dose for children and children under 7 years old.

    Used in liver and liver coma (only for adults):

    Starting dose: 30-45 ml or 2-3 packs, 3-4 times daily.

    This dose can be adjusted to the maintenance dose so that it is possible to go 2-3 times soft daily.

    Children: Safe and effective in children (newborn to 18 years old) with unpaid liver's enhancement.

    Elderly patients, kidney failure or liver failure: There is no specific dosage recommendations, due to the systemic exposure to Lactulose is negligible.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    Treatment: Stop treatment or dose reduction. Again loss due to diarrhea or vomiting may need electrolytes.

    In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

    Side Effects

    When using Duphalac Syrup Abbott 200ml, you may experience unwanted effects (ADR).

    Safety data summary

    flatulence can occur after a few days of treatment. In principle, this symptom disappears after a few days.

    diarrhea and abdominal pain may occur if the dose is higher than the instructions. If this case occurs, it is necessary to reduce the dose to correspond to the recommended dose (see overdose).

    If high doses (usually only for hepatic brain disease) for a long time, may be insomnia from electrolyte due to diarrhea.

    List of side effects

    Unwanted effects have occurred with the frequency specified below in patients treated with lactulose in clinical trials that are controlled with placebo [(very common (≥ 1/10); common (≤ 1/100 to Gastrointestinal disorders:

    Very common: diarrhea.

    Common: flatulence, abdominal pain, nausea, vomiting.

    Test results:

    Not common: electrolyte imbalance due to diarrhea.

    Children: Safety data in children is said to be similar to adults.

    Notify the doctor with unwanted effects when using the drug.

    Instructions on how to handle ADR

    If diarrhea, it is an overdose, need to reduce the dose immediately; If there is still diarrhea, stop taking the drug.

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Duphalac Siro Abbott 200ml contraindicated in the following cases:

    Hypersensitivity (allergies) with lactose or any ingredients of the drug.

    Galactose blood.

    Stomach obstruction, digestive or digestive risk.

    Be cautious when using

    consult your doctor in the case:

  • Abdominal pain is unknown before treatment.

    Patients with lactose intolerance should use duphalac syrup oral solution (see important information about excipients).

    Normal dose in constipation does not matter for diabetics. However, the dosage of treatment of brain disease is usually higher and the amount of sugar in the drug should be considered for diabetics.

    Long -term use without the adjustment of the dose or improper use can lead to diarrhea or electrolyte balance disorders.

    This drug contains lactose, galactose and a small amount of fructose. Therefore, patients with rare genetics in galactose tolerance or fructose, partially deficiency of lactase or less steamed glucose-galactose should not use this drug.

    Children: Use laxatives for children only when necessary and under medical supervision. Definition reflexes may be disordered during treatment.

    important information about excipients: Duphalac syrup oral solution contains lactose monohydrate. If you do not tolerate some lines, especially lactose, ask your doctor before taking this medication.

    The ability to drive and operate machinery

    Duphalac Syrup does not have or have a little effect on the ability to drive and operate machinery.

    pregnancy

    During pregnancy, there are no effects on embryos known by the body exposure to lactulose is negligible.

    duphalac syrup can be used during pregnancy.

    The period of breastfeeding

    No effect on infants/breastfeeding is known by the systemic exposure of nursing women for lactulose is negligible.

    duphalac syrup can be used during breastfeeding.

    Interactive drug

    There is no interactive research that has been done.

  • Storage

    In the original packaging, the temperature below 30 degrees C.

    Expiry date: 24 months from the date of production.

    Do not use overdue drugs indicated on the packaging.

    Manufacturer: Abbott Biologicals B.V.

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