Siro Tiffy Thai Nakorn Patana Treatment of nasal congestion, fever (30ml)
Dosage form Syrup
Specifications Box x 30ml
Ingredient Paracetamol, phenylephrine, chlorpheniramine
Ingredient
Thành phần cho 5ml
| Composition information | Content |
| Paracetamol | 120mg |
| Phenylephrine | 5mg |
| Chlorpheniramine | 1mg |
Uses
Indications
Tiffy Syrup drug is indicated in case of reducing common symptoms: nasal congestion, fever, pain relief and allergic rhinitis.
Pharmacokinus
tiffy syrup is an analgesic, anti -congestion fever and anti -allergic fever.
Paracetamol: Has analgesic and fever -reducing effects due to reduced prostaglandine synthesis by inhibiting cyclooxygenase enzyme system.
Phenylephrin HCl: directly causing blood vessels in the nose and upper respiratory tract, thus reducing the stuffy nose.
chlorpheniramin maleat: Has antihistamine resistance effect on H1 receptors, thus reducing the secretion of nasal and mucus in the upper respiratory tract.
Dynamic pharmacokinetics
paracetamol
Before taking Siro Tiffy Thai Nakorn Patana Treatment of nasal congestion, fever (30ml)
How to use
tiffy syrup used by oral.
Dosage
Children aged 3-6 years: 1 teaspoon (5 ml/time), 4 times/day.
Children from 6-12 years: 1-2 teaspoons (5-10 ml/time), 4 times/day.
Adults: 2 teaspoons (10 ml/time), 4 times/day.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?
paracetamol
Expression:
Management:
phenylephrin HCl
Expression: Overdose of phenylephrin causes increased blood pressure, headache, convulsions, cerebral hemorrhage, chest drumming, extra -syllable, abusive. Slow heart rate usually occurs early.
Hypertension: Hypertension can be overcome by taking α-adrenergic blockers such as phentolamine 5-10mg, intravenous injection; If necessary, can be repeated. Hemorrhage is usually not helpful. Pay attention to symptomatic treatment and general support, medical care.
chlorpheniramin maleat
The death dose of chlorpheniramin maleat is about 25-50mg/kg body weight. Symptoms and signs of overdose include sedation, inverse stimulation often central nervous system, mental disorder, seizures, apnea, convulsions, anti -secretion effects Acetylcholine, hypertonic reactions and vascular collapse, arrhythmia.
Treatment of symptoms and supporting life function, especially paying special attention to liver, kidney, respiratory, heart and water balance, electrolyte.
Stomach or vomiting with ipecacuanha syrup. Then, for activated carbon and bleach to limit absorption.
When experiencing hypotension and arrhythmia, it should be actively treated. It is possible to treat convulsions with intravenous diazepam or phenytoin intravenously. May have to be blood transfusion in heavy cases.
What to do when you forget 1 dose? However, if the time of relaxation with the next dose is too short, skip the forgotten dose and continue the calendar of Tiffy Syrup. Do not use double dose to compensate for missed dose.
Side Effects
When using Tiffy Syrup, you may experience unwanted effects (ADR).
Common, ADR> 1/100
Central nervous system: Sleeping, sedation.
Digestive system: dry mouth.
Uncommon, 1/1000 Body: Ban, Hypersensitivity reaction, restlessness, anxiety, panic, weakness, dizziness, epigastric pain or discomfort, tremor, respiration, pale or pale. Digestive system: Nausea, vomiting. Hematology system: Dehydration (neutropenemia, hypoglycemia, hematoma, hematoma), Anemia. Kidney: Kidney disease, kidney toxicity when abusing for a long time Rare, 1/10000 Body: Dizziness. Digestive system: Nausea. Instructions on how to handle ADR When experiencing side effects of Tiffy Syrup, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindications:
Tiffy Syrup drugs are contraindicated in the following cases:
Hypersensitivity to one of the ingredients of the drug.
Patients with hypertension, ventricular tachycardia, peripheral thrombosis, thrombosis of the intestine.
Patients with acute pancreatic or liver disease.
Newborns, premature babies, pregnant and lactating women, narrow -angle glaucom disease, digestive ulcers, prostate hypertrophy symptoms, asthma, bladder neck obstruction, pyloric - duodenum, patients are using Monoamine inhibitors Oxidase (Mao).
Children under 3 years old.
Be cautious when using
do not take Tiffy Syrup more than 7 days. If the pain lasts more than 5 days, you must consult a physician.
Related to paracetamol: monitor liver function, cautious cases of prolonged treatment or liver and kidney failure. Patients with alcoholics using long -term preparations can be toxic to the liver.
Regarding phenylephrin HCl: Precautions in edema patients, hemorrhage, myocardial infarction, pericardial hemorrhage, bowel necrosis, liver and kidney necrosis.
Regarding antihistamine chlorpheniramin maleat:
Patients with congenital urinary retention, a history of bronchial asthma, increased intraocular pressure, excessive thyroid gland, cardiovascular disease. Antihistamine drugs can also cause pulmonary fluids and can prevent sputum and sinus drainage.
Elderly: Antihistamine drugs can cause dizziness, fainting, hypotension, confusion. Limit by reducing the dose.
Children: Antihistamine overdose can cause hallucinations, convulsions, death. For babies causing irritation. Limitations: Use the right dose.
Be careful when coordinating with other preparations containing paracetamol, phenylephrin HCl and chlorpheniramin maleat.
Do not overdose.
paracetamol
Serious side effects on the skin, although the incidence is not high but serious, even life-threatening including Stevens-Johnson syndrome (SJS), Poisoned Skin necrotic syndrome: Toxic Epidermal Necrolysis (Ten) or Lyell syndrome, acute pustular syndrome (AGEP).
Symptoms of the above syndrome are described as follows:
Stevens-Johnson syndrome (SJS): is a puffiness, localized puffiness around the natural cavities: eyes, nose, mouth, ears, genitals and anus. In addition, it may be accompanied by high fever, pneumonia, liver dysfunction. Diagnosis of Steven-Johnson Syndrome (SJS) when at least 2 naturally damaged cavities.
Poisoned skin necrosis syndrome (Ten): is the most severe drug allergy, including:
Diverse lesions in the skin: measles, pink, pink or puffiness, damage quickly spread throughout the body.
Eye mucosa lesions: keratitis, pus conjunctivitis, corneal ulcer.
Damage to the gastrointestinal mucosa: stomatitis, mouth mucosa, pharynx, throat, esophagus, stomach, intestines.
Damage to the mucosa of genital tract, urinary tract.
There are also serious systemic symptoms like fever. Gastrointestinal hemorrhage, embryo inflammation, glomerulonephritis, hepatitis, ... high mortality rate 15 - 30 %.
Excellent pustules syndrome (AGEP): Small sterile pustules arise on the spreading platform. Damage often appears in folds such as armpits, groin and face, then can spread the whole body. Systemic symptoms are often fever, high neutrophilic blood test.
When detecting signs of rash on the first skin or any other hypersensitive reactions, patients need to stop using the drug. People who have had severe skin reactions caused by Paracetamol must not use the drug again and when they come to medical examination and treatment, they need to notify the medical staff on this issue.
Be cautious with methylparaben and propylparaben: can cause allergic reactions (may be late reaction).
The ability to drive and operate machinery
Tiffy Syrup medicine can cause drowsiness and dizziness, patients should be cautious while driving or performing jobs that need to be alert.
Unusable pregnancy
.
Nursing period
Not used.
Drug interaction
related to paracetamol
High -dose drugs along with the use of anticoagulants (Coumarin, indoDion) may increase the effect of these drugs.
Anti -convulsions (Phenytoin, Barbiturat, Carbamazepin), Isoniazide can increase the toxic liver toxic of Paracetamol.
Regarding phenylephrin HCl
The phenylephrin HCl preparations should not be used with epinephrin or other sympathetic nerve stimulants because it can cause fast heartbeat or arrhythmia.
The stimulation of the heart or increased blood pressure of phenylephrin HCl may occur when the previous use of Monoamin Oxidase (Mao) inhibitors because the metabolism of phenylephrin HCl decreases.
Atropin sulfate prevents tachycardia reflection and increases blood pressure caused by phenylephrin.
Blood pressure increases may occur if using phenylephrin HCl for patients who are using barley injection products like Ergonovin Maleat.
Regarding Chlorpheniramin Maleat may increase the effects of central neurological inhibitors.
Prolonged effects when used with Monoamin Oxidase inhibitors.
Storage
Store in a dry place, the temperature does not exceed 30 ° C.
Other drugs
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