Siro Tusspol Polfarmex Cam - Treatment of cough due to many causes (150ml)

Dosage form Syrup
Specifications Box
Ingredient Butamirate citrate

Ingredient

Thành phần cho 1ml

Composition information	Content
Butamirate citrate	1.5mg

Uses

indications

tusspol drugs are indicated in the following cases:

Indications for cough patients in all cases.

ATC code: R05DB13

Butamirate citrate, the active ingredient of tusspol, is the inhibitor, not related to the alcaloid opioids.

Butamirate Citrate works in the center, but the exact mechanism of operation of this substance is not known. Butamirate Citrate has anti -cholinergic properties and relaxes the lung stalks, making it easier for patients to breathe. Tusspol is not addictive or familiar with medicine. Tusspol is used to reduce cough in adults and children.

Dynamic pharmacokinetics

absorption

In the available data, butamirate exists in the form of ester absorbed quickly after drinking. Butamirate is metabolized through hydrolysis of metabolic substances (phenyl-2-butyric acid and diethylaminoethylanethol). There is no research on the relationship between the impact of the amount of food used simultaneously with the drug. The linear dependence between bioavailability and the dose is not yet known.

After taking 1 dose of syrup contains 150 mg of butamirate citrate, determining the concentration of the main metabolite, phenyl-2-butyric acid in plasma is 6.4 mg/ml. This concentration is achieved after about 1.5 hours after drinking.

distribution

The distribution of the drug in the body is not known. There is no data on the permeability of Butamirate Citrate from the placenta into breast milk.

transformation

Butamirate is quickly and completely hydrolyzed and formed acid and diethylaminethinethanol phenyl-2-butyric. Different animal studies show that the aforementioned metabolites have the effect of anti -them. There is no data found diethylaminoethoxeethanol in humans. Studies have been conducted among butamirate users with 1C carbon isotope, butlamirate ratio attached to plasma proteins about 95%. Hydroxylation continues metabolites that produce phenyl-2-butyric acid products.

Elimination

The three metabolites described above are excreted mainly through the kidneys in the form of assembled with glucuronic acid. There is a big difference in the measured value of the sale time of the syrup: in a 6-26 hours (the maximum value is 41 hours).

Before taking Siro Tusspol Polfarmex Cam - Treatment of cough due to many causes (150ml)

How to use

oral medication.

Dosage

Patients who use only non -prescribed drugs of a doctor for 1 week.

Children from 3 to 6 years old: 5 ml of syrup (containing 7.5 mg butamirate citrate) used 3 times/day.

Bamboo from 6 to 12 years old: 10 ml of syrup (containing 15 mg butamirate citrate) used 3 times/day.

Adolescents over 12 years: 15 ml of syrup (containing 22.5 mg butamirate citrate) used 3 times/day.

Adults: 15 ml of syrup (containing 22.5 mg butamirate citrate) used 4 times/day.

tusspol should be used before meals.

tusspol does not specify children under 3 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? In case of overdose, washing the intestine or using adsorbent coal powder should be considered. Patients should be monitored and important functions to be maintained. No special detoxification data.

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using tusspol drugs, you may experience unwanted effects (ADR) such as:

Nervous system disorders:

Rare (≥1/10 000 to

Disorders of the digestive system:

Rare (≥1/10 000 to

Skin disorders and subcutaneous tissues:

Rare (≥1/10,000 to

Instructions on how to handle ADR:

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Tusspol drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Butamirate citrate inhibits cough reflexes, in the case of patients with phlegm can cause mucus accumulation in the respiratory tract, increasing the risk of bronchospasm and respiratory infections.

If the cough lasts more than 7 days, the patient should find the doctor's advice.

tusspol contains sorbitol, patients with rare genetic problems of fructose intolerance should not be used. The drug has a light laxative effect. Each gram of sorbitol releases 2.6kcal.

The effect of the drug on driving and operating machinery

tusspol can cause symptoms of dreaming, drowsiness, so it should not be used when operating machinery and trains.

Use drugs for women during pregnancy and lactation

There has been no study to establish safety and effectiveness of using drugs on pregnant and lactating women.

tusspol should not be used in the first 3 months of pregnancy. For the rest of pregnancy, patients can use the drug.

There is no data on the excretion of the active ingredients and metabolites of the drug in breast milk. For safety reasons, pregnant women should not use butamirate citrate.

Drug interaction

The studies on drug interaction have not been established.

Butamirate Citrate inhibits cough reflexes, in the case of patients with phlegm should avoid using the drug.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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