Soft tablets Teburap 120mg Dongkoo treat peripheral circulation disorders (10 blisters x 10 tablets)

Dosage form Soft capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Ginkgo Biloba Leaf Extract
Indication Tinnitus, tooth loss, dizziness
Contraindication Pregnancy, drug allergy, coagulation disorders

Ingredient

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Composition information	Content
Ginkgo Biloba Leaf Extract	120mg

Uses

indications

Teburap drug indicated in the following cases:

Treatment of peripheral circulating disorders (limp). Seeing the inhibition of platelet aggregation, and showing "the effect of cleaning free radicals". It seems that it also inhibits the production of histamine and leukotrien. It also shows the ability to inhibit muscarin -type effects on cholinoCeptor and 2 - adrenoceptor. It can change the properties of blood flow.

European ginkgo products sold in the form of EGB 761 have shown the stimulating effect on the vestibular multiplication neurons (LVN) and printing - vitro and printing studies - Vivo shows increasing the recording of the Synap of 5 - hydroxytryptamine.

This drug also shows the blockage of ascorbic/Fe2+ acid, causing a decrease in the movement of the Synap body membrane. "The previous occupation of neuron lipids is caused by ascorbic/Fe2+ acid along with the movement reduction of the membrane, which reduces the ability to transport dopamine to collect dopamine."

Ginkgo Biloba extract (ginkgo) slow down the consumption of O2 (respiratory effort) of irritated cells by inhibiting NADPH - OXID, enzymes responsible for the decomposition of O2 to O2-. As a result, the production of Superoxid (O2-) and hydrogen peroxide (H2O2) is significantly reduced when PMNS stimulation is made in the presence of drugs at concentrations of 500, 250 and 125 micrograms/ml. Moreover, the generation of hydroxyl (OH) radicals is greatly reduced at low concentrations of 15.6 micrograms of GBE/ml, which shows that the extract also has the activity of cleaning free radicals. GBE
is likely to at least significantly reduce the activity of myeloperoxidase in neutrophils.

Dynamic pharmacokinetics

on animals, after taking the extract with carbon 14, studying the absorption and distribution of the drug shows the absorption quickly and completely. The radioactive balance in 72 hours shows the release in CO2 exhaled and in the urine.

Radioactive measurement in the blood over time creates pharmacokinetic parameters and shows that the semi -biodegradable time is about 4 hours 30.

Radioactive peak in the blood is achieved after 1 hour and 30, the absorption occurs in the upper part of the digestive tract.

Research on the distribution of radioactive tissue shows the affinity of the eye and some types of nodes and nerves, especially the hypothalamus, and the body.

Ginkgolid A bioavailability is recorded on humans 98 - 100%, Ginkgolid B is 79 - 93% and bilobalid is over 70% or more.

A study of 12 volunteers showed that after taking a single dosage high, the ginkgo dose of 0.90mg to 3.36mg while hungry stomachs showed high levels of bioavailability. This level is represented by the average values (+/- sd) of the bioavailability coefficient (FAUC) with values of 0.8 (+/- 0.09), 0.88 (+/ 0.21) and 0.79 (+/- 0.30) corresponding to Ginkgolid A, Ginkgolid B, and Bilobalid.

Food does not change AUC value but increases Tmax.

LD50 in the mice, LD50 is 7725mg/kg, the drug is used by oral 2 times a day. Therefore, toxicity is considered very low.

Before taking Soft tablets Teburap 120mg Dongkoo treat peripheral circulation disorders (10 blisters x 10 tablets)

How to use

oral, oral drugs, during or after meals.

Dosage

recommended dose:

Peripheral, dizziness, tinnitus disorders: 1 tablet/day. Dosage can be adjusted depending on age, or severity of symptoms.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

rarely causes mild digestive disorders, in some special cases that can cause allergies, circulatory disorders (reducing blood pressure, dizziness, headache, tachycardia), insomnia, skin allergies. Drugs.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Teburap drug contraindicated in the following cases:

There is a history of sensitivity to the ingredients of the drug.

Be cautious when used

Do not replace drugs to treat hypertension, not for myocardial, brain, brain hemorrhage.

Using drugs for women during pregnancy and lactation

Safety when used for pregnant women is not known. No Teburap background for pregnant women. Do not use in breastfeeding women because Teburap is excreted for breast milk or not.

The effect of the drug on the ability to drive and operate machinery

There has been no record of the drug on the ability to drive and operate machinery.

Interactive drugs

Pain to treat painful aspirin, persantin, ticlid brain complications.

anticoagulant drugs, anti -platelets, hematurian drugs.

Valproat anti -epileptic drugs.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

Other drugs

Disclaimer

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