Solufemo Hataphar oral solution for treatment and prevention of anemia (20 tubes)

Dosage form Oral solution
Specifications 20 tube box
Ingredient Iron (III) Hydroxyd Polymaltose

Ingredient

Thành phần cho 10ml

Composition information	Content
Iron (III) Hydroxyd Polymaltose	100mg

Uses

indications

Solufemo drug indicated in the following cases:

Treatment and prevention of iron deficiency anemia, iron supplements. Iron (III) Hydroxid Polymaltose Complex is used to treat abnormalities in red blood cells due to iron deficiency. Iron stimulating erythrocytes, nor does Hemoglobin disorder in iron deficiency cause.

Iron complex (III) Hydroxid Polymaltose is a complex of iron oxidation molecules that can be soluble in water including iron (III) multi -core hydrolysis hydrolysis hydoxid (polymaltose). The nucleus of iron (III) multi -core hydroxid is covered with a polymaltos molecule that is not jointly treated together to create complex molecules including approximately 52,300 Dalton. This complex is sustainable and in physiological conditions, not releasing iron ions. The iron in the nucleus of this multi -core molecule is connected in a structure similar to the structure of ferritin in terms of physiological. Due to these chemical and pharmacokinetic properties, iron (III) Hydroxid Polymaltose Complex is suitable for oral iron replacement.

Dynamic pharmacokinetics

iron complex III Hydroxid Polymaltose have good bioavailability.

Normal iron is absorbed in the duodenum and pink head. Absorption is supported by the acid secretion of the stomach and some acids in the diet. Absorb also increases in iron deficiency conditions or in a vegetarian state but is reduced if the body is overloaded. Iron absorption depends on the amount of iron reserved, especially ferritin, in the intestinal mucosa and on the body's red blood cell speed.

After absorbing, iron is separated immediately with protein to form hemosiderin or ferritin, or partially forming transferrin. Finally, iron binds to protein, supplementing the shortage of iron and joining hemoglobin. Iron is stored in the body in two forms: ferritin and hemosiderin.

In the absence of bleeding (including menstruation), only a small amount of iron is lost daily. Most of the losses occur through the cells of the gastrointestinal tract and a smaller amount is lost and urine. About 99% of iron put into the body is discharged through feces.

Before taking Solufemo Hataphar oral solution for treatment and prevention of anemia (20 tubes)

How to use

oral solution. Drugs for oral right after meals. Do not take medicine when lying.

Dosage

Dosage and treatment time depend on the level of iron deficiency. Daily dose can be divided into separate dose.

Treatment of iron deficiency in adults and teenagers (children over 12 years):

Take 100mg to 200mg iron (10 - 20ml) per day.

Prevention of iron deficiency in adults and teenagers (children> 12 years old) is at high risk:

Take 100mg of iron (10ml) per day.

or a higher dose as directed by the doctor.

Regularly monitor hematology parameters and iron concentrations to evaluate patients' response for treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms:

Overdose of iron (III) Hydroxid Polymaltose Complex is less likely to cause acute poisoning. However, exceeding the need for restoring hemoglobin and supplementing iron reserves can cause hemosiderin infection. Symptoms of overdose include slipping such as epigastric pain, nausea, drowsiness, pale, purple, even coma, liver failure and kidney failure; When iron concentration in serum> 300 micrograms/ml, need to be treated for serious toxicity.

How to handle:

Overdose treatment by causing vomiting immediately, if it is necessary to carry out the gastric wash and apply other supportive therapies. Although rare, but if the iron overdose occurs seriously (when the serum iron concentration exceeds the total iron bonding capacity), it can be treated with Deferoxamine. This intravenous injection may be slowly detoxified (80mg/kg body weight for 24 hours) or intramuscularly (14-90mg/kg body weight, every 8 hours. Deferoxamin is linked to free iron circulation in the form of iron (III). This detox also creates complex with iron ion (III) of ferrintin and hemosiderin to form iron complex (III), red in red (FerrioMine) Tieu.

Avoid using deferoxamine for patients who are progressive renal failure.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

Very common (ADR 1 ≥ 10):

Digestive: black stool.

Common (1/100 Digestive: diarrhea, nausea, indigestion.

Rare (1/1000 digestive: vomiting, constipation, abdominal pain, tooth color change

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Solufemo drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Caution when using

Patients with liver failure or kidney failure: Caution when used.

Elderly patients: No dose adjustment for the elderly except for kidney failure.

Do not take medicine when lying.

Use drugs for women during pregnancy and lactation

No report.

The impact of drugs when driving or operating machinery

The drug is used for people who are driving or controlling machinery.

Drug interaction

When drinking iron (III) Hydroxid Polymaltose and tetracyclin, plasma tetracyclin concentration does not decrease below the level necessary for the effectiveness of treatment.

The drug can reduce the absorption of methyldopa, the quinolones when taken.

Antihistamine H2 reduces iron absorption when taken with.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

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