Sopelen 500mg BCWorld medicine treats conscious disorders (3 blisters x 10 tablets)
Dosage form Box of 3 blisters x 10 tablets
Specifications Citicoline
Ingredient
| Composition information | Content |
| Citicoline | 500mg |
Uses
indications
Sopelen tab. Used in the following cases:
The role of lecithin in regeneration shows the use of citicolin the pharmacological effects on the central nervous system, protecting the central nervous system against many toxic substances (lack of oxygen, toxic organic solvents and nerves ...) have seen the correlation between brain damage and neurological disorders and phospholipid deficiency in diseased areas.
Phospholipid regeneration requires cholin's merger into phosphatidyl for Lin, which is the process to be done through citicolin. Therefore, using citicolin to treat neurological dysfunction at advanced age (dizziness, migraine, fatigue, insomnia, memory loss, physical decline, posture disorders and disorders of social communication functions) damage brain after surgery and brain thrombosis.
Pharmacokinetics
absorption
citicolin absorbs well after oral, absolute bioavailability of the drug is approximately 99%. Because it is difficult to determine the citicolin level in plasma, the tests only determine the free cholin concentration or the total radioactive capacity of plasma within the limit of a amount equivalent to citicolin.
Cholin concentration in plasma increases significantly after drinking. On the radiation spectrum obtained after taking citicolin 300 mg, there are two peaks equivalent to citicolin. The first peak appears after 24 hours of medication (3 mcg/ml), and maybe this is the cause of slow absorption and continues to accumulate medication after this period.
Distribution
cholin is obtained from citicolin through the bloody barrier, perhaps the source of raw materials for synthesizing acetylcholin and lecithin (phosphatidylcholin). A large amount of citicolin is in the form of combining tissues and/or used in biosynthetic and degenerative paths, including lecithin synthesis/cell lipid.
Metabolism
Metabolic drugs in the liver into a free cholin form. The liver has the ability to synthesize lecithin from cholin and re -synthesize citicolin from cytidin and cholin.
Elimination
A small amount of drugs are excreted through urine (2-3%) and feces (less than 1%). There are approximately 12% of the drug excreted such as respiratory dioxide carbon. The selling time of citicolin is 3.5 hours (the first peak concentration) and 125 hours (the second peak concentration).
Before taking Sopelen 500mg BCWorld medicine treats conscious disorders (3 blisters x 10 tablets)
How to use
Take oral use.
Dosage
Occupational dose is commonly used
Take 1-2 tablets/day.
Disorders of head injury or after brain surgery
1 tablet/time, 1-2 times/day.
Support for mobility restoration with patients with hemiplegia after a stroke, 2 capsules/day/day for 3-4 weeks.
Parkinson's disease shows severe tremor
1 tablet/time/day for 3-4 weeks.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?
What to do when forgetting 1 dose?
Not recorded.
Side Effects
When using Sopelen Tab., You may experience unwanted effects (ADR).
Instructions on how to handle ADR
When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Sopelen tab. Contraindications in the following cases:
Pregnant and lactating women.
Caution when using
citicolin is often considered safe and well tolerated. Drinking plenty of citicolin causes low blood pressure, fat diarrhea (non -digested fat should be eliminated in the stool), vomiting, nausea, diarrhea, increased salivation, constipation, anorexia, dizziness, sweating and headache. Citicolin can activate existing epilepsy.
Dosage at the above amount limit (UL) is contraindicated for people with trimethylamine in urine, Parkinson's disease, kidney disease or liver disease.
The ability to drive and operate machinery
Due to some side effects when using the drug can affect the ability to drive and operate machinery, need to be cautious when taking the drug for these objects.
Pregnancy
contraindicated.
breastfeeding period
contraindicated.
Drug interactions
do not coordinate with meclofenoxat or centrofenoxin. Because citicolin increases the effect of levodopa, it is careful when combining these two drugs.
Storage
Store in closed packaging, avoid light, avoid moisture, temperature below 30 ° C.
Other drugs
Disclaimer
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