Spirilix Pymepharco medicine treatment of schizophrenia (2 blisters x 15 tablets)

Dosage form Box of 2 blisters x 15 tablets
Specifications Sulpiride

Ingredient

Composition information	Content
Sulpiride	50mg

Uses

Indications

Spirilix 50mg is indicated in the treatment of acute and chronic schizophrenia mental illnesses, and mental disorders, anxiety, depression, dizziness, stomach ulcers.

Pharmacokinus

Sulpidi belongs to the benzamid group, which has an anti -mental disorder effect through the selective block of Dopamine D2 receptors in the brain. Sulpides can be considered an intermediate medication between neuroleptics and antidepressants, because sulpides have both of these effects. Sulpidi is mainly used to treat psychosurine diseases such as schizophrenia. The mood increases after a few days of treatment, accompanied by loss of frantic symptoms of the disease.

Sulpidi does not cause loss of emotions like when using classic neuroleptics such as phenothiazin or butyrophenon.

Sulpiride high doses control the positive symptoms of schizophrenia, but low doses have the effect of active, agile for people with indifferent schizophrenia, cowering without contact with society.

Dynamic pharmacokinetics

Sulpidi slowly absorbed through the gastrointestinal tract, low bioavailability and depending on the individual. Sulpidi peak concentration reached 3 to 6 hours after taking 1 dose. Quickly distributed into tissues, through breast milk
but through poor brain barriers. The drug is associated with low plasma proteins (

Elimination drugs through urine and distributed mainly in the form of unprovered (about 95%). Half life eliminated about 8 - 9 hours.

Before taking Spirilix Pymepharco medicine treatment of schizophrenia (2 blisters x 15 tablets)

How to use

Spirilix 50mg Pymepharco hard capsules for oral.

Dosage

Dosage of schizophrenia treatment in adults and children over the age of 14:

A negative symptom of schizophrenia: Starting or taking 200 - 400 mg/time, twice a day. If necessary, a maximum dose of 800 mg/day, 2 times a day. If necessary, a maximum dose of 1.2 g/day, 2 times a day.

People with renal failure: Must reduce the dose or increase the distance between drug use depending on the clearinine clearance.

Creatinine clearance 30 - 60 ml/minute: use the dose equal to 2/3 of the normal dose. 2 and 3 times compared to normal people.

However, in case of medium and severe renal failure should not use sulpides, if possible.

What do

do when overdose? Clinical symptoms vary depending on the dose. The overdose can be manifested by the signs of excitement, confusion, coma, hypotension.

Management: Sulpidi has no specific antidote. Therefore, the stomach should be washed when medication, drinking carbon, alkalinizing urine to increase the exhaust. Use other supportive treatments and symptomatic treatments.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Spirilix 50mg, you may experience unwanted effects (ADR).

Sulpidi is well tolerated. Using treatment dose can cause insomnia or drowsiness, temporary prolactin increase and recover, increase milk secretion, menstrual disorders.

Risen with extracurricular syndrome, Parkinson's syndrome, nervous stimulation, and prolonged QT interval. Rarely suffer from large breasts in men, lower blood pressure, arrhythmia.

Some other reactions such as lower body heat, sensitive to light, jaundice due to cholestasis.

Notice the unwanted physician when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

spirilix 50mg contraindicated in the following cases:

Patients who are sensitive to the ingredients of the drug.

Caution when using

need to be cautious when using drugs in the elderly, severe kidney failure, Parkinson's disease, epilepsy, a history of seizures (formerly or recently).

Do not drink alcohol during treatment.

affects the ability to drive and operate machinery

Do not drive or operate machinery during the use of the drug due to the drowsiness of the drug.

Pregnant and lactating women

should be cautious when using the drug during pregnancy and the dose decreases at the end of pregnancy.

The excretion of breast milk is estimated to be 1/1000 of the daily dose. Therefore, should not be used in breastfeeding women.

Drug interaction

should be cautious when coordinating with Levodopa because of the correlation against the painting between Levodopa and the neuroleptic drugs.

Simultaneously used with alcohol can increase the sedative effect of neuroleptics.

Concentrated with anti -hypertension drugs can increase the effect of lowering blood pressure and can cause vertical hypotension (due to the co -effect).

Concomitance other central neurological inhibitors (antidepressants, antihistamines H1 have sedative effects, barbiturates, sedative drugs, clonidin, sleeping pills, methadone) can increase the central neurological inhibition, causing bad consequences, especially drivers and operating machinery.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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