Stadgerri Stella skin cream treats skin diseases (10g)

Dosage form Tube
Specifications Clotrimazole, betamethasone dipropionate, Gentamicin

Ingredient

Thành phần cho 10g

Composition information	Content
Clotrimazole	1%
Betamethasone dipropionate	0.064%
Gentamicin	0.1%

Uses

indications

Stadgertri drug stella is indicated in the following cases:

Treatment of skin diseases that respond to corticosteroids when bacterial infection complications (sensitive to gentamicin) and fungi (sensitive to clotrimazole) or when there is suspicion of these infections. Skin combined with anti -inflammatory and itching properties of betamethasone with antifungal activity of clotrimazol and the broad antibacterial activity of Gentamicin Sulfate.

Betamethason dipropionate is a fluorized synthetic corticosteroid. At the treatment dose, corticosteroids mainly have anti -inflammatory and/or immunosuppressive effects. Located corticosteroids such as Betamethason Dipropionate are effective in the treatment of dermatitis thanks to anti -inflammatory, anti -itching and vascular effects. However, while the physiological, pharmacological and clinical effects of corticosteroids are clear, the exact impact mechanism in each disease is uncertain.

Gentamicin Sulfate is an antibiotic of the aminoglycosides that kill bactericidal effects through inhibiting bacterial protein biosynthesis. The actual gentamicin antibacterial spectrum includes Gram -negative aerobic bacteria and staphylococcus aureus, including strains producing penicillinase and methicillin resistance.

Clotrimazol is a broad spectrum antifungal. The mechanism of acting of clotrimazol is linked to phospholipids in the fungal cell membrane, changing the permeability of the membrane, causing loss of intracellular essential substances that lead to the destruction of mushroom cells.

Dynamic pharmacokinetics

betamethasone is easily absorbed when used on the spot. When applied, especially if the skin is closed or when the skin is torn, there may be a amount of betamethasone that is absorbed enough for the whole body effect.

Gentamicin sulfate is usually not absorbed through the skin intact after application; However, the drug is easily absorbed through the skin where the skin is not intact or the skin is no more keratin like wounds, burns or ulcers.

Used on the skin, clotrimazol is very few absorbed: six hours after applying the cream, 1% Clotrimazol radioactive on the skin intact and on acute inflammatory skin, clotrimazol levels change from 100 micrograms/cm3 in the horny layer to 0.5 - 1 microgram/cm3 in the spine layer and 0.1 micrograms

Before taking Stadgerri Stella skin cream treats skin diseases (10g)

How to use

Stadggri Stella is only used on the skin. Apply a thin layer of cream to the sick.

Dosage

Youth and adults

should apply a thin layer of cream that covers the entire surface of the sick and surrounding skin 2 times/day, in the morning and evening. From 2 - 12 years old

should only apply a small amount to the sick and gently rubbed skin. Date.

For effective treatment, should be applied regularly.

Variable treatment time depends on the area and position of the patient's disease and response.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

using topical corticosteroids can inhibit the pituitary -adrenal function, leading to secondary adrenal disabilities and causing signs of adrenal secretion, including Cushing.

There is almost no overdose when using clotrimazole on the spot.

Single -dose Gentamicin is almost no symptoms. Using Gentamicin in place too much or prolonged can be further broadcast due to the growth of uncertainty bacteria.

Treatment

Need to indicate appropriate symptomatic treatment. Symptoms of acute corticosteroids often recover. Treatment of electrolyte imbalance if necessary. In the case of chronic poisoning, corticosteroids should be stopped slowly. If the growth of bacteria is not sensitive, stop using stadggri and conduct other appropriate therapies.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Stadgentri Stella , you may experience unwanted effects (ADR).

Local skin disorders may occur if treatment on the skin area is wide, tight or prolonged treatment such as skin atrophy (especially on the face), capillary dilatation, skin pattern, strip-like skin atrophy, skin bleeding, steroid acne, blushing (Rosacea) or dermatitis (skin syndrome). Restorate or not). there. em).

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Stadgertri Stella contraindicated in the following cases:

contraindicated to use topical corticosteroids in cases of skin infections (viruses, bacteria [including tuberculosis bacteria] and mushrooms), reacting to vaccines, skin ulcers and acne. Do not apply cream on the face in case of blushing (Rosacea) or dermatitis around the mouth. Apply stadggri to the mucosa, the skin around the eyes and close to the eyes.

Be cautious when using

stop using stadggri and apply appropriate treatments if irritated or hypersensitively.

The whole body absorption of the active ingredients when used on the spot may increase if the drug is used on a large skin, especially for a long time or on the injured skin.

In such cases, any unwanted effect has been reported when using the whole body sugar can occur when used on the spot. Appropriate prevention, especially for children.

It is necessary to consider the risk of toxic accumulation (toxicity on the ear, toxicity on the kidneys) due to increased skin absorption when used simultaneously with systemic aminoglycosides.

There may be cross allergies with other aminoglycosides.

Long -term use of antibiotic preparations can develop uncertainty microorganisms. In this case or in case of superinfection, the appropriate treatment should be started.

It is necessary to have a close monitoring of a doctor when applying high -dose corticosteroids with strong or very strong active groups on a large skin area or an area of topical topical skin, especially paying attention to the inhibition of endogenous corticosteroids and the ability to act on metabolism.

Avoid use on open wounds and damaged skin.

Do not take the drug continuously for 2-3 weeks.

It is necessary to be especially cautious when using corticosteroids very strong, strong and medium active group on the face or genital area, and should only be used for 1 week.

On the skin around the eyes, corticosteroids should only use mild activity (due to the risk of glaucoma).

corticosteroids can cover skin allergies to the ingredients of the drug.

Only use drugs for existing skin diseases and do not share drugs with others.

visual disorders may occur when using systemic and topical corticosteroids (including nasal lines, inhalation and eye lines). If the patient has symptoms such as blurred vision or other visual disorders, the patient should be transferred to an ophthalmologist to assess the causes that can cause visual disorders, which may include cataracts, glaucoma or rare diseases such as central retinopathy (CSCR) that has been reported after the use of body corticosteroids.

Do not use this medicine for children under 2 years old.

Pediatric patients may be more sensitive to the inhibition of the hypothalamus activity-Yen-HPA (HPA) due to topical corticosteroids and the effects of external corticosteroids compared to adult patients because of more absorption due to the proportion of skin surface area on large body weight.

Inhibiting HPA axis (manifestation of low cortisol levels in plasma and non -response to ACTH stimulation), Cushing syndrome, growth slowly, slow weight gain and intracranial hypertension (including inflamed, headache and thorns on both sides) have been reported in children using local corticosteroids.

Stadgentri contains Cetyl Alcohol (Emulcire 61 WL 2659), which can cause local reactions on the skin (such as contact dermatitis).

Stadggri contains methyl p-hydroxybenzoate and propyl p-hydroxybenzoate, which can cause allergic reactions (late).

Stadgentri contains propylene glycol, which can cause skin irritation.

Pregnant women should only use Stadggri when really necessary. Do not use stadggri on a wide surface area, with a large amount of medicine or for a long time.

Do not breastfeed when using stadggri on the breast.

The drug does not affect the ability to drive and operate machinery.

The ability to drive and operate machinery

unknown effects of the drug.

Pregnancy

There is no clear and complete research on the teratogenic ability of topical corticosteroids on pregnant women. Therefore, the steroids should only be stopped during pregnancy when the treatment benefits are higher than the potential risk to the fetus. Do not apply large amounts on a large amount or for a long time for pregnant women.

The period of breastfeeding

Because it is not known whether the use of local corticosteroids can lead to enough body absorption to be able to find in breast milk or not, should decide to stop breastfeeding or stop the drug, consider the importance of the drug for the mother.

Drug interaction

No data.

Storage

In closed packaging. In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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