Stadxicam 15 Stella medicine to treat osteoarthritis, rheumatoid arthritis (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Meloxicam

Ingredient

Composition information	Content
Meloxicam	15mg

Uses

indications

Stadxicam 15 drugs are indicated in the following cases:

Treatment of rheumatoid arthritis, treatment of short -term symptoms of severe acute osteoarthritis and treat symptoms of vertebrae. Meloxicam's anti -inflammatory activity has been shown on the classic forms of inflammation.

As other NSAIDs, the exact mechanism of action has not been well known. However, at least one common mechanism of the NSAID group (including Meloxicam) is to inhibit prostaglandin biosynthesis - an intermediate that causes inflammation.

Pharmacokinetics

absorption

Meloxicam is well absorbed after drinking.

Distribution

99% of the drug is connected to plasma proteins. The distribution volume increases when renal failure.

Metabolism

The drug is metabolized mainly through oxidation.

Elimination

Meloxicam has a half -life of plasma for about 20 hours, excreted one by urine and feces, less than 5% of the dose is excreted in a constant form.

Before taking Stadxicam 15 Stella medicine to treat osteoarthritis, rheumatoid arthritis (3 blisters x 10 tablets)

How to use

used by oral.

Dosage

Anti -arthritis and rheumatitis:

Meloxicam is used at a normal single dose of 15 mg/day.

People at high risk of side effects, should start at a dose of 7.5 mg/day.

Severe acute osteoarthritis:

Meloxicam's daily daily dose is 7.5 mg, if necessary to increase to a maximum single dose of 15 mg/day.

Elderly: Long -term treatment in the elderly with a dose of 7.5 mg/day.

Permanent kidney failure: Meloxicam is often contraindicated in patients with severe renal impairment.

However, in patients with a separation, Meloxicam can be used at a dose of 7.5 mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Gastrointestinal bleeding can occur.

A few cases of severe poisoning can lead to hypertension, acute renal failure, liver dysfunction, respiratory failure, coma, convulsions, heart failure and cardiac arrest. Anaphylactic reactions may occur during the overdose.

Handling: Patients need to be controlled for symptoms and support treatment at NSAID overdose. Meloxicam elimination can be accelerated by using 4 g cholestyramin orally 3 times/day.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Stadxicam, you may experience unwanted effects (ADR).

Very common (1/10

Digestive: indigestion, nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea.

Common, ADR> 1/100

Neurological: headache.

Uncommon, 1/1000

Digestive: gastrointestinal bleeding, stomatitis, gastritis, belching.

Other disorders: anemia, dizziness, sleep, itching, rash, blushing, increased transaminase or bilirubin.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Stadxicam drug 15 Contraindications in the following cases:

Hypersensitivity to Meloxicam or any ingredients of the drug.

History of urticaria, angioedema, bronchospasm, severe rhinitis, or shock when combined with aspirin or other NSAID drugs.

History of sensitive to aspirin, asthma and nasal polyps. Severe liver failure.

Severe renal failure is not separated.

Gastrointestinal bleeding, History of blood vessel hemorrhage.

Be cautious when using

Heart thrombosis:

Non -steroid anti -inflammatory drugs (NSAIDs), non -aspirin, using systemic sugars may increase the risk of cardiovascular thrombosis, including myocardial and dumb infarction, can lead to death. The risk of cardiovascular thrombosis is recorded mainly at high doses.

Doctors need to periodically evaluate the appearance of cardiovascular events, even if the patient has no previous cardiovascular symptoms. Patients should be warned of symptoms of serious cardiovascular events and need to visit the doctor as soon as they appear.

To minimize the risk of adverse incidents, the lowest -daily -daily -daily -daily stadaicam is required in the shortest possible time.

Effects on the gastrointestinal tract:

The risk of serious effects on the gastrointestinal tract (such as bleeding, ulcers, perforation), may occur any time or without warning signs and symptoms.

Hypertension:

Using NSAID drugs, including meloxicam that can cause hypertension or worsen available hypertension, this case increases the incidence of cardiovascular disease.

Effects on the kidneys:

Nephrotic necrosis or renal change may occur when long -term use of NSAID drugs.

Hypersensitivity reaction:

Hypersensitivity reactions include anaphylactic reaction that may occur in patients without the sensitivity to the previous Meloxicam.

Hematology effects:

Anemia has been reported, mainly occurring in patients using long -term meloxicam (about 6 months).

Stadxicam 15 contains lactose. This medication should not be used for patients with rare genetic problems galactose intolerance, total lactase enzyme deficiency or poorly absorbed glucose-galactose.

The ability to drive and operate machinery

There is no specialized research on the ability to drive and operate machinery. However, based on the pharmacological mechanism and side effects of Meloxicam, it shows that the drug does not affect or affect the ability to drive and operate machinery. However, if there are serious side effects such as dizziness, drowsiness, need to stop driving or operating machinery.

Pregnancy

Avoid taking the drug in the last 3 months of pregnancy because it is likely to cause early closing fetal artery. The ability to slow labor when taking the drug at the end of pregnancy.

Breastfeeding

meloxicam excreted in mice, should stop breastfeeding or stop taking the drug because of the dangerous ability in breastfed babies.

Interactive drug

NSAID drugs and acetylsalicylic acid> 3 g/day. Combined with other nonsteroidal anti -inflammatory drugs, including acetylsalicylic acid with anti -inflammatory doses (single doses of 21g or total daily doses of 23 g) are not indicated.

corticosteroids: Be careful when used with corticosteroids because of the increased risk of bleeding or stomach ulcers.

Anticoagulants or heparin indicated for the elderly or at the treatment dose: increasing the risk of bleeding, through inhibition of platelet function and destroying the stomach lining.

Diuretics, enzyme inhibitors and Angiotensin II antagonists: NSAID drugs can reduce the effects of diuretics and other anti -hypertension drugs.

Other anti -hypertension drugs (such as beta channel blockers): like these drugs, reducing the hypotension effect of beta channel blockers (due to prostaglandin inhibitors with vasodilation effects).

Cyclosporin: The kidney toxicity of cyclosporin may increase when using NSAID through the intermediate effect of prostaglandin in the kidney.

Lithi: NSAID drugs are reported to increase the concentration of lithium in the blood (through reducing lithium excretion in the kidneys), which can lead to toxic threshold.

methotrexate: NSAID drugs can reduce the secretion of methotrexate in the renal tubules due to increased methotrexate levels in plasma.

cholestyramin: Cholestyramin increases the elimination of meloxicam by preventing the liver -intestinal cycle, so the clearance of Meloxicam increases by 50% and the selling time decreases to 13+3 hours.

Storage

Store in closed packaging, dry place, avoid moisture. The temperature does not exceed 300C.

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