Sucrafil Fourts Media treat arthritis, gastroesophageal reflux (200ml)

Dosage form Drink
Specifications Bottle x 200ml
Ingredient Sucralfate
Indication Gastritis, gastroesophageal reflux, ulcerative colitis

Ingredient

Thành phần cho 10ml

Composition information	Content
Sucralfate	1g

Uses

indications

Sucrafil drugs are indicated in the following cases:

Short -term treatment of progressive duodenal ulcer (up to 8 weeks) in duodenal ulcer.

Treatment or prevention of damage to the gastrointestinal mucosa (ulcer and bleeding) due to stress, especially in patients being rescued emergency.

Pharmacy

Pharmacological group: Drugs acting on the gastrointestinal tract.

ATC code: A02bx02

Sucralfat is an anti -ulcer agent that inhibits pepsin's protein resolution. It produces protective membranes on inflammatory or ulcerative of the stomach and protects the stomach lining against the ability to absorb pepsin, trypsin and bile acids. Sucralfate - Aluminum Hydro Sulphat Sulphate complex - is a mucosal protective agent. In the stomach (pH

Sucralfate is bound to phosphorus on the gastrointestinal tract and reduces phosphorus concentration in plasma, while calcium levels may increase. Sucralfat also helps protect the surface of the ulcer to avoid damage by inhibiting the pepsin enzyme, which is the enzyme that breaks down the mucosa protein. Sucralfat increases the synthesis of prostaglandin E2 and the stomach lining, protecting the stomach. It is also associated with epithelial growth factors and fibroblasts.

Dynamic pharmacokinetics

have up to 5% of the disacaride part and less than 0.02% aluminum is absorbed into the body after taking a sucralfate dose. Most of the drugs are eliminated to feces, only a small amount of disacarid sulfate discharged into urine.

Before taking Sucrafil Fourts Media treat arthritis, gastroesophageal reflux (200ml)

How to use

oral medication.

Dosage

The usual dosage of adults is 10 ml of X 3-4 times/day between meals and before going to bed.

Short -term treatment for duodenal ulcer

The recommended dose for adults with duodenal ulcer is 10 ml (equivalent to 1g) x 4 times/day, drink 1 hour before each meal and before going to bed or 20 ml (equivalent to 2g) x 2 times/day when waking up and before going to bed when the stomach is empty. Anti -acid agents can be indicated when necessary to relieve pain but should not be taken within half an hour before or after taking sucralfat. While the wound healing process may be within 1-2 weeks of treatment, it is advisable to continue using it within 4-8 weeks, unless the endoscopic or X -ray results show that the ulcer has healed completely.

Preventive treatment for duodenal ulcer or maintenance treatment after healing duodenum ulcer

10 ml x 2 times/day, drink before breakfast and dinner half an hour when the stomach is empty. Should continue to maintain treatment for 12 months. Typically, the solid sucrafil is effective in patients with stomach ulcers, but a short -term therapy combined with painkillers and spasms can bring greater benefits in some new patients with clinical manifestations, especially patients with abundant pain in the epigastric area.

Short -term treatment for benign stomach ulcers and gastrointestinal symptoms related to arthritis treatment with nonsteroidal anti -inflammatory drugs

10 ml of x 3 or 4 times/day between meals and before going to bed.

Treatment and prevention of mucosal lesions due to stress

10 ml of x 4 times/day between meals and before going to bed for no more than 14 days.

Gastroesophageal reflux

10 ml of x 3 or 4 times/day between meals and before going to bed.

Elderly

Be careful when choosing the dose for older patients, usually starting from the lowest dose in the dose range because the elderly often impair the heart, kidney, liver and accompanying or simultaneous disease.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Due to less experience in the doses of sucralfate, there is no recommendation for special sucralfate overdose. Sucralfat is very little absorbed on the gastrointestinal tract, so the risk of acute overdose is very small.

In case of overdose, most patients do not show symptoms. Should treat symptoms and support treatment.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Sucrafil, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Constipation diarrhea.

Unknown frequency

Digestive: diarrhea, nausea, stomach discomfort, dry mouth.

nerve: dizziness, drowsiness.

Other: skin rash, itching and back pain. Systemic: allergic reactions (including urticaria, edema, difficult respiration, rhinitis, larynx spasm and face edema).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Sucrafil drugs contraindicated in the following cases:

Patients sensitive to any ingredient of the drug.

Children under 15 years old.

Be cautious when used

Be cautious when taking this medication for patients with renal failure because it can increase aluminum absorption.

In patients with severe renal impairment or hemolysis, sucralfate may be used extremely carefully and in a short time. Simultaneous treatment of this medication and aluminum -containing drugs are not recommended for the ability to absorb aluminum toxicity. Sucralfate may also cause allergic reactions (may be slow).

duodenal ulcer is a chronic disease, easy to relapse. When short -term treatment with sucralfate can heal completely, successfully sucralfate is not thought to change the frequency of recurrence or the severity of the duodenal ulcer.

Safety and efficiency when taking the drug lasting for more than 12 months has not been studied. If the patient feels full of abdominal, vomiting, vomiting and abdominal pain after eating, you should consult your doctor immediately.

If unintentional injection, sucralfate and insoluble excipients can lead to death complications, including brain and lung congestion. Therefore, no sucralfate intravenous injection. Use sucralfate and nutrition through the steam, so it is about 1 hour due to the risk of forming benzoar due to sucralfate. The bezoar (insoluble pieces are formed with gastric lumens) sometimes occurs in patients using sucrafil. Most of these patients are at risk of forming a benzoar in the stomach such as: slow stomach hollow or using nutrition through the steam.

The ability to drive and operate machinery

The use of sucrafil can lead to special drowsiness when used simultaneously with alcohol and can be dangerous when driving or operating machinery or any activity that needs high mental focus.

pregnancy

Because there is no adequate and good control of the use of sucralfat in pregnant women, only sucrafil for pregnant women if really necessary.

The period of breastfeeding

It is unknown whether the drug is given to breast milk or not. Therefore, be careful when using sucrafil for breastfeeding patients.

Drug interaction

Simultaneous use of Sucrafil may reduce the bioavailability of some drugs including: Tetracyclin, Ciprofloxacin, Norfloxacin, Ketoconazole, Digoxin, Phenytoin, Theophylin, Thyroxin, Quinidine and antacids H2.

The bioavailability of these drugs is not affected by taking these drugs and sucrafil mixture 2 hours apart. This interactive mechanism is not sent by the body absorption, mainly as a result of sucralfate cohesion with simultaneous medications on the digestive tract. Because Sucrafil can change the absorption from the gastrointestinal tract of some drugs, Sucrafil and other drugs should be considered separately if the use simultaneously significantly changes the bioavailability of these drugs.

Simultaneous use of sucralfate and antacids is not recommended because antacids can affect the ability to attach sucralfate to the mucosa. Therefore, it is recommended to use sucralfate and antacids 30 minutes apart.

Use sucrafil and nutrition through the steam, so about 1 hour in patients using sucrafil to prevent digestive ulcers due to stress. In a few cases, the formation of benzoar has been formed by sucrafil and nutrition through the steaming tube too close.

Storage

Store at temperatures below 30 ° C. Avoid sunlight.

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