Sucralfate Vidipha Treatment of duodenal ulcer - stomach (2 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 2 blisters x 10 tablets
Ingredient Sucralfat
Indication Gastroesophageal reflux, heartburn

Ingredient

Composition information	Content
Sucralfat	1g

Uses

indications

Sucralfate is indicated in the following cases:

The drug used to treat duodenal ulcer, gastric ulcer benign, chronic gastritis. developed. The drug has a local effect (ulcer) than the whole body. When there is gastric acid, the drug forms a complex like a lake powder attached to the damaged mucosa.

Sucralfate does not neutralize much of stomach acid. Sucralfate treatment dose does not have an acid -resistant effect, but when adhering to the stomach - duodenum mucosa, the acid neutralization effect of sucralfate can become important to protect at the ulcer. The drug has a strong affinity (6-7 times higher than the normal stomach lining) for ulcerative area and affinity for duodenal ulcers larger than stomach ulcers. Sucralfat has created an ulcerative protective barrier. This fence has inhibited pepsin's protein elimination effects by preventing Pepsin assigning to albumin, fibrinogen ... found on the ulcer surface. This fence also prevents the diffusion of glycocholic acid and protecting the gastric mucosa is not damaged by taurocholic acid. However, the effect of sucralfate on bile acid in the treatment of peptic ulcer is unclear. Sucralfat is considered to be a gastrointestinal mucosa protective drug with the meaning of creating a fence in the ulcer to protect ulcers from pepsin, acid and bile -causing ulcer and therefore ulcers can be immediately. The drug is considered a protective drug of the gastrointestinal mucosa.

The drug appears after 1-2 hours and the time is up to 6 hours.

Dynamic pharmacokinetics

Absorption: Very little absorption (

Distribution: unknown.

Metabolism: non -metabolic drugs.

Elimination: 90% excreted into the feces, a very small amount is absorbed and excreted into the urine in the form of constant compounds.

Before taking Sucralfate Vidipha Treatment of duodenal ulcer - stomach (2 blisters x 10 tablets)

How to use

Used by oral, should take sucralfat when hungry, drink before meals or before going to bed.

Dosage

Adults and children over 15 years old:

duodenum ulcer, gastritis: drink 2g/ time, drink 2 times a day (in the morning and before going to bed) or 1 g/ time, 4 times/ day (drink 1 hour before meals and before going to the army), for 4 to 8 weeks, if needed can be used up to 12 weeks. Maximum dose of 8g/day. Treatment until the ulcer is healed (endoscopic test), usually requires 6-8 weeks of treatment. If the patient has a clear evidence infected with Helicobacter pylori, it also needs to be treated to eliminate H.pylori bacteria with minimum with metronidazol and amoxicillin, in combination with sucralfate and with an anti -acid drug such as H2 histamine inhibitors or proton pump inhibitors. Treatment should not last for more than 6 months. Thick intestine when ulcers due to stress: Take 1 g/ time, 6 times/ day. Maximum dose of 8g/day. Must be cautious when used.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Management: Immediately report to the doctor in case of overdose or over -dose.

What to do when forgetting a dose? But if it's almost time for the next dose, only use the following dose. Do not use double dose or add a dose to compensate for the dose to forget to drink.

Side Effects

When using sucralfate, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: constipation .

Uncommon, 1/1000

digestive: diarrhea , nausea, vomiting, bloating, indigestion, flatulence, dry mouth. 1/1000

Hypersensitivity reactions: urticaria , edema, difficult to worship, rhinitis, larynx spasm, enlarged face.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Sucrafate drug contraindicated in the following cases:

Hypersensitivity to sucralfat or any ingredient of the drug.

Be cautious when used

Use carefully in people with renal failure due to the risk of increased aluminum accumulation in serum; Show is when used for a long time. In case of severe renal failure, avoid use.

The ability to drive and operate machinery

should be cautious when driving or operating machinery due to drugs that can cause unwanted effects of drowsiness, dizziness, dizziness.

Pregnancy

has not determined the harmful effects on the fetus. The drug absorbs very little through the gastrointestinal tract. However, when you are pregnant, you should take the drug in case of need.

Breastfeeding period

It is unknown whether sucralfat is excreted in milk or not. If there is an excretion on breast milk, it will also be very little, because the drug is absorbed into the body.

Drug interaction

can use antacids along with sucralfate in the treatment of duodenal ulcer to mitigate pain, but do not drink at the same time because antacids can affect the sucralfate attachment on the mucosa. Should drink antacid before or after taking sucralfat /4 hours.

Cimetidin, ranitidin , ciprofloxacin, norfloxacin , ofloxacin, digoxin , warfarin, phenytoin , Theophylin, Tetracyclin when drinking with SucralFate will reduce the absorption of absorption. So take these drugs 2 hours before or after taking sucralfat.

Simultaneous use of citrate with sucralfate may increase the concentration of aluminum in the blood. Therefore, sucralfate should not be used with citrate preparations.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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