Sucrapi drug 1000mg/5ml apimed treatment for peptic ulcer (20 packs)

Dosage form Drink
Specifications Box of 20 packs
Ingredient Sucralfate
Indication Peptic ulcer, gastroesophageal reflux

Ingredient

Composition information	Content
Sucralfate	1000mg

Uses

indications

Sucrapi oral fluid containing the active ingredient is Sucralfat, which is a substance of the gastrointestinal mucosa, acting by creating a protective barrier in the ulcer and preventing irritation caused by acid, pepsin and bile.

Sucrapi oral fluid is used in:

Treatment of duodenal ulcer, benign stomach ulcers, chronic gastritis.

Pharmacological group: Protection of gastric mucosa; Treatment of stomach and duodenal ulcer.

ATC code: A02BX02

Sucralfate is an aluminum salt of sulfate disacarid, used for short -term treatment of duodenal and stomach ulcers.

The drug has a local effect (ulcer) than the body effect. When there is gastric acid, the drug forms a complex like a lake powder sticking to the damaged mucosa. Sucralfat does not neutralize many stomach acid levels. The treatment dose of sucralfate has no acid anti -acid effect, but when adhering to the gastric - duodenal mucosa, the acid neutralization effect of sucralfate can become important to protect at the ulcer.

The drug has a strong affinity (6-7 times higher than the normal stomach lining) for ulcerative area and affinity for duodenal ulcers larger than stomach ulcers. Sucralfat has created an ulcerative protective barrier. This fence has inhibited pepsin's protein elimination effects by preventing pepsin from attaching to albumin, fibrinogen ... available on the ulcer surface. This fence also prevents the diffusion of H+ ions by interacting directly with acid on the ulcer surface.

Sucralfate also absorbs bile acids, inhibits diffusion back to glycocholic acid and protects the gastric mucosa from being damaged by taurocholic acid. However, the effect of sucralfate on bile acid in the treatment of peptic ulcer is unclear. Sucralfat is considered to be a gastrointestinal mucosa protective drug with the meaning of creating a fence in the ulcer to protect ulcers from pepsin, acid and bile -causing ulcer and therefore ulcers can be immediately. The drug is considered a protective drug of the gastrointestinal mucosa.

pharmacokinetics

Absorption: very little absorption (

Distribution: unknown.

Metabolism: non -metabolic drugs.

Elimination: 90% excreted into the feces, a very small amount is absorbed and excreted into the urine in the form of constant compounds.

Before taking Sucrapi drug 1000mg/5ml apimed treatment for peptic ulcer (20 packs)

How to use

Sucrapi drinks should be taken at hunger, drink before meals or before going to bed.

Dosage

Dosage for adults and teenagers aged 15 and over:

Treatment of duodenal ulcer, gastritis

Take 2 g (10 ml)/ time, 2 times/ day (in the morning and before going to bed) or drink 1 g (5 ml)/ time, 4 times/ day (take 1 hour before meals and before going to bed). benign stomach

Take 1 g (5 ml)/ time, 4 times/ day.

usually treat for 6 - 8 weeks. Proton).

Take 1 g (5 ml)/time, 2 times/day.

Take 1 g (5 ml)/time, 4 times/day.

Maximum dose of 8 g (40 ml)/day.

Take 1 g (5 ml)/time, 6 times/day.

Maximum dose of 8 g (40 ml)/day.

It is not recommended to use Sucrapi oral fluid for children under 15, unless there is a doctor's advice.

Do not take overdose.

What to do when overdose?

Most cases of overdose are asymptomatic, some cases show signs of abdominal pain, nausea and vomiting. Studies on acute toxicity on animals, using a dose of up to 12 g/kg body weight have not been found to cause death. Therefore the risk of overdose is very low.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose?

If you forget a dose, use it as soon as possible. However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

Digestive: constipation.

Uncommon, 1/1 000

Digestive: We flow, nausea, vomiting, bloating, indigestion, flatulence, dry mouth.

Skin exterior: itching, erythema.

Neurology: dizziness, dizziness, insomnia, nausea.

Other side effects: back pain, headache.

Rare, ADR

Hypersensitivity reactions: itching, urticaria, rhyme, shortness of breath, rhinitis, larynx spasm, enlarged face.

Instructions on how to handle ADR: Unwanted effects of sucralfat are rare and also rarely stop the drug.

Warnings

Contraindicated

Do not use this drug for people who are allergic to sucralfat or any ingredient of the drug.

Precautions when using

Need to be cautious and notify the doctor or pharmacist when taking this medication to the patient has the following problems:

People with renal failure

Pregnant women or are planning to become pregnant

breastfeeding women

Use carefully in people with renal failure due to the risk of increased aluminum accumulation in serum, especially when used for a long time. In case of severe renal failure, avoid use.

Do not use the supplement of the sucrapi for intravenous injection, the possible complications are aluminum poisoning, pulmonary and brain embolism, death.

Sucrapi oral fluid is not recommended for dialysis.

Avoid using simultaneously with aluminum -containing drugs because of the increase in aluminum absorption and toxicity.

The ability to drive and operate machinery

When using the drug may occur dizziness, drowsiness, so patients should pay attention when driving or operating machinery.

Women during pregnancy and lactation

Pregnant women: Not determined to be harmful to the fetus. The drug absorbs very little through the gastrointestinal tract. However, when pregnant should only take the drug in case of essential.

Lactating women: It is unknown whether or not the sucralfate will be excreted in milk or not. If excreted in breast milk, the amount of sucralfate will also be very small, because the drug is absorbed into the body very little. However, be careful when using sucrapi for pregnant women.

Drug interaction

Can use antacids along with sucralfate in the treatment of duodenal ulcer to mitigate pain. But do not drink at the same time as antacids can affect the attachment of sucralfate on the mucosa. You should tell patients to take Antacid before or after taking Sucralfat 30 minutes.

Cimetidin, ranitidin, ciprofloxacin, norfloxacin, ofloxacin, digoxin, warfarin, phenytoin, theophylllin, tetracyclin, ketoconazole, sulpid, levothyroxine, quinidine when taken with Sucralfate
will reduce the absorption. So take these drugs 2 hours before or after taking sucralfat.

Simultaneous use of preparations containing citrate with sucralfate may increase the concentration of aluminum in the blood. The mechanism is due to the formation of aluminum chelate that increases the absorption.

Storage

Store in a dry place, avoid light, temperature below 30 ° C, not to freeze.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.