Sufat Hasan emulsion treatment for stomach and duodenal ulcer (30 packs x 2g)

Dosage form 30 package box
Specifications Sucralfat

Ingredient

Composition information	Content
Sucralfat	1g

Uses

Indications

SUFAT 1G HASAN is indicated in the following cases:

Adults and children over 15 years old:

Short -term treatment (up to 8 weeks) duodenal ulcer, benign stomach ulcer, chronic gastritis.

Prevention of stomach bleeding - intestines when ulcers due to stress.

esophagitis.

Preventive stomach - duodenal ulcer.

Children under 15 years old:

Preventive ulcerative prophylaxis in children is being treated for a strong treatment, treatment of benign ulcer - benign stomach.

Pharmacokic

Sucralfat is aluminum salt of sulfate disaccarid, used for short -term gastrointestinal ulcer. The drug has a more local effect (ulcer) than the whole body effect. When there is gastric acid, the drug forms a complex like a lake powder sticking to the damaged mucosa. Sucralfat does not neutralize many stomach acid levels. The treatment dose of sucralfate has no acid anti -acid effect, but when adhering to the gastric - duodenal mucosa, the acid neutralization effect of sucralfate can become important to protect at the ulcer.

Sucralfat has a strong affinity for the ulcer area (6-7 times higher than the normal gastric mucosa) and the affinity for the duodenal ulcer is larger than the thick ulcer. Sucralfat produces an ulcerative barrier, which inhibits pepsin's protein elimination effects by preventing Pepsin from attaching to albumin, fibrinogen ... on the ulcer surface. This fence also prevents the diffusion of H+ ions by interacting directly with acid on the ulcer surface.

Sucralfate also absorbs bile acids, inhibits diffusion back to glycocholic acid and protects the gastric mucosa from being damaged by taurocholic acid. However, the effect of sucralfate on bile acid in the treatment of stomach - duodenal ulcer is unclear. Sucralfat is considered to be a protective drug of the gastrointestinal mucosa, creating a fence in the ulcer to protect the ulcer not pepsin, acid and bile -causing bile and therefore the ulcer can be immediately. Sucralfat is considered as a protective drug of the gastrointestinal mucosa.

The drug appears after 1-2 hours and the time is up to 6 hours.

Sucralfat's

clinical data in children is limited. Depending on each country that has indicated by different ages.

pharmacokinetic

absorption

Sucralfat absorbs very little (

Distribution

Sucralfat distributes very small amounts into tissue, does not determine whether the drug is through the placenta and secretion into the milk or not.

Metabolism

Sucralfate reacts with hydrochloride acid in the stomach into non -metabolic sucrose sulfate.

Elimination

90% of sucralfate is excreted in the feces, a very small amount is absorbed and excreted into the urine in the form of constant compound.

Before taking Sufat Hasan emulsion treatment for stomach and duodenal ulcer (30 packs x 2g)

How to use

Take medicine at an empty stomach, 1 hour before every meal and in the evening before going to bed. Mix 1 pack into half a glass of water to form a homogeneous mixture before drinking.

Can use antacids to relieve pain, but should not be taken for 30 minutes before or after taking sucralfat.

Dosage

Adults and children over 12 years old

Treatment of duodenal ulcer, chronic gastritis

2 packs (2g/time x 2 times/day) in the morning and before going to bed or 1 pack (1g/time x 4 times/day), drink 1 hour before meals and before bed, for 4-8 weeks, if needed can be used up to 12 weeks. The maximum dose of 8 packs (8g/day).

Treatment of benign stomach ulcers

1 pack (1g/time x 4 times/day). Treatment continues until the ulcer heals (tested by laparoscopy). Usually require 6-8 weeks of treatment. If the patient has a clear election of Helicobacter pylori infection, the minimum treatment of H. pylori is required with metronidazol and amoxicillin, coordinating sucralfate and acid secretion (H2 histamine inhibitors or proton pump inhibitors).

Prevention of duodenal ulcer

1 pack (1g/time x 2 times/day). Treatment does not last more than 6 months. Recurrent duodenal ulcer caused by H. pylori bacteria, to eliminate H. pylori, need a new session of sucralfate to combine antibiotics.

Prevention of stress ulcer

1 pack (1g/time x 4 times/day). Maximum dose of 8g/day.

Prevention of stomach bleeding when ulcers due to stress

1 pack (1g/time x 6 times/day. Maximum dose 8g/day.

Children under 15 years old

Dacellular form of 1g oral solution is not suitable for children from 1 month - 12 years old.

children 12 - 15 years old

Preventive ulcerative prophylaxis in children being treated for a strong treatment, treatment of duodenal ulcer - benign stomach

1 pack (1g/time x 4 - 6 times/day).

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

In clinical trials in healthy women overdose sucralfat, most of them have no symptoms, some cases appear symptoms of abdominal pain, nausea, vomiting. Animal toxicity testing in animals with a dose of up to 12g/kg still does not identify toxic doses. So the risks related to very small overdose.

There is no information on how to deal with sucralfat overdose.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using 1g Hasan SUFAT, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: constipation.

Uncommon, 1/1000

Digestive: dry mouth, nausea.

Rare, 1/10000

Digestive: The object in the stomach.

DA: rash.

Unknown frequency

The immune system: Hypersensitivity reaction (itching, urticaria, angioedema, shortness of breath).

nerve: dizziness, headache, drowsiness. digestive: diarrhea, vomiting, discomfort gastrointestinal, indigestion, belching.

musculoskeletal joints: back pain, bone chaos, soft bone.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

SUFAT 1G HASAN Contraindicated in the case:

Hypersensitivity to SucralFAT or any ingredients of the drug.

Be cautious when used

Do not use sucralfate intravenously due to can lead to aluminum poisoning and other deadly complications, including pulmonary obstruction, brain obstruction.

Be cautious in patients with renal impairment due to the risk of increased aluminum accumulation. It is not recommended to use sucralfate in mitosis patients. In patients with severe renal impairment or chronic renal failure, using sucralfate must be extremely cautious and only short -term. A small amount of aluminum is absorbed through the gastrointestinal tract and may be accumulated. Bone dysplasia, soft bone, brain disease, anemia has been reported in patients with renal impairment. It is recommended to test the concentration of aluminum, phosphate, calcium, alkaline phosphatase regularly with patients with impaired renal function.

It is not recommended to simultaneously use other aluminum preparations because of the increased risk of aluminum absorption and poisoning.

The objects in the stomach have been reported after using sucralfat mainly in patients with serious illnesses using enhanced medical equipment. Most patients with diseases may increase the risk of formation of foreign objects (slowly emptying the stomach due to surgery, drug use or diseases that reduce movement).

The ability to drive and operate machinery

Sucralfate can cause unwanted effects on the nerves such as dizziness, dizziness, drowsiness. Doctors and pharmacists need to notify the patient, in case the patient has the above unwanted effects, must not drive, operate machinery, work on high or other jobs that can cause other dangers that require alertness and concentration.

Pregnancy

has not determined the harmful effects on the fetus. Sucralfate absorbs very little through the digestive tract. However, during pregnancy, the drug should only be used in the case of essential.

Breastfeeding period

No sucralfat has not been determined in breast milk or not. If excreted in breast milk, the amount of sucralfate will also be very small, because the drug is absorbed into the body very little. Be cautious when using sucralfate in nursing women.

Medicinal interaction

can use antacids and sucralfate in the treatment of duodenal ulcer to mitigate pain. But do not drink at the same time as antacids can affect the attachment of sucralfate on the mucosa. Tell patients to take Antacid before or after taking Sucralfat 30 minutes.

Concentrated with Sucralfat can reduce the bioavailability of some drugs such as fluoroquinolon (Ciprofloxacin, Norfloxacin), Tetracyclin, Ketoconazole, Sulpid, Digoxin, Warfarin, Phenytoin, Theophylline, Levothyroxin, quinidine, quinidine, antagonistic medicine. The bioavailability of the above drugs is restored to the old sucralfate. This interaction may be because the above drugs are clinging to the sucralfate in the gastrointestinal tract.

Do not use simultaneously sucralfat with citrate -containing preparations because it can create chelate complexes with aluminum increases the amount of aluminum absorption, increasing aluminum concentration in blood.

Should avoid simultaneous use of sucralfate with nourishing through the gastrointestinal tract by nasal - stomach catheter in preventing ulcers due to stress. Although rare, there have been cases of forming objects in the stomach when the time of using sucralfate and placing the nose -nose catheter nurtured through the digestive tract is too close to each other.

Storage

Where dry, less than 30 ° C, avoid light.

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