Sulpiride 50mg Imexpharm drugs treat schizophrenia (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Sulpiride

Ingredient

Composition information	Content
Sulpiride	50mg

Uses

indications

Sulpiride 50mg Imexpharm drug indicated for acute and chronic schizophrenia treatment.

Pharmacokinus

Sulpidi belongs to the benzamid group, which has an anti -mental disorder effect through the selective block of Dopamine D2 receptors in the brain. Sulpidi gives sedative and antidepressant effects but does not cause much sleep or emotional loss like other sedatives.

Dynamic pharmacokinetics

Sulpiride slowly absorbed through the gastrointestinal tract, low bioavailability and depending on the individual. The peak concentration of Sulpidi reaches 3 to 6 hours after taking a dose. The drug is quickly distributed into the tissue, through breast milk but through the blood -brain barrier. The drug is linked to low plasma proteins (

Before taking Sulpiride 50mg Imexpharm drugs treat schizophrenia (10 blisters x 10 tablets)

How to use

oral medication.

Dosage

Adults:

A negative symptom of schizophrenia: The starting dose of 200 - 400 mg/time x 2 times/day. In case of necessity, a maximum of 800 mg/day can be increased. In case of necessity, a maximum of up to 1200 mg/time can be increased 2 times/day.

Children over the age of 14: Take 3 - 5 mg/kg/day.

Dosage for the elderly is similar to adults but the starting dose is low, from 50 - 100 mg/time x 2 times/day, then increases to the effectiveness.

Dosage reduction or increase the distance between drug use depending on the clearinine clearance. However, the recommendation should not be used in case of medium and severe renal failure.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Clinical symptoms when overdose will vary and depending on the dose:

dose of 1g - 3g: can cause a state of gloomy, restlessness, rare symptoms of foreign tower. Symptoms are usually lost within hours. The coma when using high doses can last up to 4 days. If the patient is new to medication, gastrointestinals should be washed and active (the drug causes no vomiting), alkaline urine to increase the elimination of the drug. If necessary, use Parkinson's syndrome medication, combined with other supportive treatments and symptomatic treatments.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Sulpiride 50mg often has unwanted effects (ADR) such as:

Common

Insomnia or drowsiness, increased blood prolactin, increased milk secretion, menstrual disorders or amenorrhea.

Excessive stimulation, outsider syndrome (sitting restless, crooked neck, eye rotation), Parkinson's syndrome, prolonged QT interval (causing arrhythmia, torsion).

Big breasts in men, late dysplasia, Malignant high fever syndrome due to neuroleptics, vertical blood pressure, slow heart rate or arrhythmia, lower body heat, sensitive to light, jaundice due to cholestasis.

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Sulpiride 50mg Imexpharm drugs contraindicated in the following cases:

Hypersensitivity to sulpida.

Be cautious when used

reduce the dose of sulpides and increase monitoring for patients with renal impairment. It is necessary to treat each interrupt wave when the patient has severe renal failure.

Strengthen monitoring during treatment for the following subjects:

People with epilepsy because they are likely to be lowered. Low -dose sulpides can make severe symptoms.

Pregnant or lactating women

Pregnant women: Sulpidi through the placenta, which can cause unwanted effects on the fetus's nerves. Therefore, patients should not take drugs during pregnancy, especially in the first 16 weeks of pregnancy.

Lactating women: Sulpidi is distributed into breast milk in relatively large amounts and causes unwanted reactions for breastfed babies. Therefore, women who are breastfeeding should not be used or stop breastfeeding if used.

The effect of drugs on the ability to drive train and operate machinery

The drug can cause drowsiness, should avoid using the drug when driving the train and operating machinery.

Medicinal interaction

Sucralfate or antacids containing aluminum or Magnesi hydroxyd reduces sulpidi absorption. Therefore, Sulpidi should be used after taking antacids for about 2 hours to avoid interaction.

Lithi: Increases the ability to attach sulpides to the dopaminergic d2 receptor in the brain, increasing the risk of sulpided pagan disorders.

levodopa: Antagonism competes with sulpides and sedatives. Contraindicated coordination Sulpida and Levodopa.

Alcohol: Increasing the sedative effect of the drug. Avoid drinking alcohol and alcoholic beverages during use.

Hemotrogate medications: may increase the effect of lowering blood pressure and can cause vertical hypotension. It should be noted when coordinated.

Other central neurological inhibitors: Increasing neurological inhibition effects, which can cause bad consequences, especially drivers and machinery operators. It should be noted when coordinated.

Storage

less than 30 C, avoid moisture and light.

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