Sulpiride Stella 50mg drug treatment for anxiety (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Sulpiride

Ingredient

Composition information	Content
Sulpiride	50mg

Uses

indications

Sulpiride 50mg Stella drugs are used in the following cases:

Treatment of short -term symptoms of anxiety in adults in case of failure with normal treatments. The drug also helps to support the nerve.

Dynamic pharmacokinetics

absorption: Slow absorption in the digestive tract, low bioavailability, depending on the differences of individuals.

Distribution: The drug is quickly distributed to tissues but less through the brain barrier, less than 40% of sulpiride combined with plasma proteins. Sulpiride is distributed to breast milk.

Elimination: The drug is excreted mainly through urine and feces, in a constant form. Selling time for plasma is about 8-9 hours.

Before taking Sulpiride Stella 50mg drug treatment for anxiety (5 blisters x 10 tablets)

How to use

oral medication.

Dosage

adults:

Short -term treatment of anxiety symptoms in adults in case of failure with normal treatment:

Use 50 - 150 mg/day for up to 4 weeks.

schizophrenia:

Patients with negative symptoms:

Starting 200 - 400 mg, 2 times/day, if needed to a total dose is 800 mg/day.

Patients with positive symptoms:

400 mg/time, 2 times/day, if the dose is needed to a maximum of 1.2 g/time, 2 times/day.

Patients with symptoms of yin and positive combination:

400 - 600 mg/time, 2 times a day.

Children over the age of 14:

Use 3 - 5 mg/kg/day.

Elderly patients:

Start 50 - 100 mg/time, 2 times a day, then adjust the dose when needed.

Patients with renal failure:

Clcr = 30 - 60 ml/minute: 2/3 compared to normal doses or can extend the distance between the dose 1.5 times compared to normal people.

Clcr = 10 - 30 ml/minute: 1/2 compared to normal doses or may extend the distance between doses 2 times compared to normal people. CLCR

The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Symptoms of clinical poisoning vary depending on the dose.

Single dose from 1-3g causes a gloomy, restless consciousness. The dose from 3-7g can cause excitement, confusion and foreign symptoms. The dose over 7g can also be in a coma and hypotension. Symptoms are usually lost in a few hours. The coma can last up to 4 days after high doses.

Management: Sulpiride is partly excluded through hemolysis. There is no specific antidote. The treatment is only a symptom. Therefore, it is advisable to start appropriate supportive treatment solutions, closely monitor important functions and cardiovascular control until the patient recovers.

Can be treated with alkaline urine, if necessary, use Parkinson's syndrome medication. Need to monitor coma and cardiovascular control until the patient recovers. The drug causes vomiting is not sure to be effective in the treatment of sulpiride overdose.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Sulpiride Stella 50mg, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Neurological: Insomnia or drowsiness.

Endocrine: increased blood prolactin, increased milk secretion, menstrual disorders or amenorrhea.

Uncommon, 1/1000

Excessive stimulation, pagoda syndrome (sitting restless, crooked neck due to spasms, eye rotation), Parkinson's syndrome; Prolonged qt range (causing arrhythmia, torsion).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

hypersensitivity to sulpides or any ingredients of the drug.

adrenal marrow.

Granting porphyrin metabolism disorders.

The central nervous state is inhibited, comatose, alcohol poisoning and neurological inhibitors.

U depends on prolactin.

The first 16 weeks of pregnancy and nursing women.

Children under 14 years old.

Be cautious when used

In cases of renal failure, dose reduction and increase monitoring of patients. If the renal failure is severe, it is recommended to treat each interrupt batch.

Need to strengthen monitoring when treating with sulpiride patients with epilepsy, manic or mild mania, elderly patients with dementia.

It is necessary to identify all risk factors for venous thrombosis (VTE) before and during treatment and implementation of preventive measures.

Gradually reduce the dose when stopping the drug due to acute cessation symptoms (nausea, vomiting, sweating and insomnia), the possibility of recurrence of neurotic symptoms and the appearance of non -autonomous movement disorders (such as restless sitting, hypertonic disorders, movement disorders) may occur when sudden stopping the drug.

Do not drink alcohol or use alcohol preparations during treatment.

Stop absolute medicine in the case of unexplained high fever.

The drug contains lactose and starch excipients. This medication should not be used for patients with rare genetic problems galactose intolerance, total lactase enzyme deficiency or poorly absorbed glucose-galactose; Patients with wheat allergies (unlike coeliac) should not be taken.

The ability to drive and operate machinery

The drug can cause drowsiness, affecting driving or operating machinery, especially at the beginning of treatment.

Pregnancy

Not used for pregnant women, especially in the first 16 weeks of pregnancy.

The period of breastfeeding

The drug distributed into breast milk in relatively large amounts and can cause unwanted reactions for breastfed babies. Hence should be avoided for breastfeeding women.

Drug interaction

Sucralfat or antacid drugs: simultaneous use with sulpiride reduces the absorption of the drug. Therefore, it is necessary to use sulpiride 2 hours away before taking these drugs.

Lithi: Used with lithium causing extra sub -reactions.

levodopa: Contraindicated in combination with sulpiride due to antagonism competition with neuroleptics.

Alcohol: Increasing the sedative effect of the drug. Avoid drinking alcoholic foods when taking this drug.

Hemotrogate medications: may increase the effect of lowering blood pressure and may lower the vertical blood pressure, note when coordinated.

Other central neurological inhibitors: shared, increasing the central neurological inhibitor. Used with the following drugs causing torsion or extending the QT range:

Diltiazem, Verapamil, Clonidin, Digitalis.

Need to adjust the electrolyte imbalance when combined treatment:

IIA anti -arrhythmic drugs such as Quinidin, Disopyramide. (Iv), halofantrine, pentamidine.

Storage

Store in a dry place, temperatures below 30ºC, avoiding light.

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