Sunmesacol Sun Pharma treats acute ulcerative ulcer (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Mesalamine

Ingredient

Composition information	Content
Mesalamine	400mg

Uses

indications

Sunmesacol is indicated in the following cases:

Indications for the treatment of acute to medium to medium acute ulcerative and in maintaining colon ulcer. Acute and for maintenance treatment. Mesalamin is a weak inhibitor of cyclooxygenase. Mesalamin inhibits prostaglandin synthesis in intestinal plain muscle cells. The Leucotriene is made up of the lipogenase path also contributes to the birth of colon ulcer and Mesalamin is a inhibitor of lipoxygenase. Therefore, the release of Leukotriene, especially LTB4, and the release of hydroxyicosatetraenoic acid (HETE) is inhibited by Mesalamin.

The other effects of mesalamine are:

(a) Limit the movement of macrophages into inflammatory tissue. (e) Inhibit the oxidation of fatty acids.

There are about 28% of Mesalamin in Sunmesacol tablets are absorbed after taken and the rest for local impact and excretion through feces.

The absorption of mesalamin is similar during the abdomen or hunger.

Mesalamin is absorbed will be quickly acetyl in the intestinal wall and liver.

The drug is excreted mainly through the form of n-acetyl-aminosalicylic acid.

Before taking Sunmesacol Sun Pharma treats acute ulcerative ulcer (5 blisters x 10 tablets)

How to use

Sunmesacol drug Used orally.

Dosage

Acute treatment: 6 tablets/day, dosage division, simultaneous treatment with corticosteroids when clinical indications.

Maintain treatment: recommended dose 3-6 tablets/day, dosage or prescribed by a doctor.

Special case:

Children: Safety and effectiveness have not been completely established in this age group.

Elderly: Because the elderly patients are more likely to be impaired renal function, should be cautious when prescribing this drug. All recommended patients must be assessed for kidney function before starting to use Mesalamine and during treatment. Be careful to strictly control the number of blood cells during treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Sunmesacol is an aminosalicylate and symptoms of Salicylate toxicity that can also occur such as dizziness, tinnitus, headache, confusion, drowsiness, sweating, increased ventilation, vomiting and diarrhea. Severe poisoning caused by salicylate can lead to electrolyte imbalance and blood pH, increase in temperature and dehydration.

Because mesalamine is an aminosalicylate, the standard treatment for Salicylate poisoning may be beneficial in the case of acute overdose. This treatment may include preventing drugs from entering the gastrointestinal tract by causing vomiting and if the gastric pump is needed. In balance of fluid and electrolytes can be adjusted by appropriate infusion intravenous transmission. Must monitor adequate kidney function.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Sunmesacol , you may experience unwanted effects (ADR).

Common, ADR> 1/100:

Digestive: diarrhea , indigestion, nausea, abdominal pain, blood pepper (hemolysis diarrhea), rectal stimulation, severe symptoms of ulcerative colitis.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Sunmesacol contraindicated in the following cases:

On patients, it is known to be hypersensitivity to mesalamin, any ingredients of the drug, or salicylate.

Sunmesacol is not recommended for people with hypersensitivity to any component of the drug in the last period of pregnancy.

Increasing the tendency to hemorrhage due to drugs that can reduce the pH of the small intestine or the large intestine.

Be cautious when using

Because the kidney toxicity is related to the dosage on experimental animals, Mesalamin preparations are not recommended for patients with kidney disease or renal function.

Sunmesacol is an aminosalicylate and symptoms of Salicylate toxicity can also occur such as dizziness, tinnitus, headache, confusion, drowsiness, sweating, ventilation, vomiting and diarrhea.

Severe poisoning causes Salicylate can lead to electrolyte imbalance and blood pH, increase temperature and dehydration.

The ability to drive and operate machinery

does not drive and participate in dangerous tasks until determining how the drug can affect the ability to drive and operate machinery.

pregnancy

mesalamin through the placenta fence. Sunmesacol should be used during pregnancy only when necessary.

Breastfeeding period

Small amount of Mesalamine is distributed in breast milk and amniotic fluid of pregnant women when treated with Mesalamin.

Be cautious when using Sunmesacol on breastfeeding women.

Drug interaction

unknown dangerous interactions may have. However, Lactulose catabolism is caused by bacteria and related agents that produce organic acids that reduce the intestinal pH in the colon and thus inhibit the Eudragit S. thus should not be used simultaneously with Sunmesacol with other slow -released release preparations.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding light.

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