Syrup Rinofil 2.5mg/5ml Abbott for allergic rhinitis (15ml)

Dosage form Bottle x 15ml
Specifications Desloratadine

Ingredient

Thành phần cho 5ml

Composition informationContent
Desloratadine2.5mg

Uses

indications

Rinofil Syrup 2.5 mg/5 ml drugs are indicated in the following cases:

  • reduce symptoms in the nose or not in the nose related to seasonal allergic or allergic allergies. Desloratadin inhibits histamine released from In vitro. After drinking, desloratadin selectively inhibits the peripheral H1 histamine receptors because the drug cannot completely penetrate into the central nervous system.

    Desloratadin also has anti -allergic effects from in vitro studies. Inhibiting the release of inflammatory cytokines such as IL - 4, IL - 6 and IL - 13 nursing words as well as inhibiting the release of the p - selectin -stick molecules of the cell membrane.

    Dynamic pharmacokinetics

    can detect desloratadine concentration in plasma within 30 minutes after taking the drug. Desloratadin absorbs well to the peak concentration in plasma after about 3 hours, the sale time is about 27 hours. The accumulation of desloratadin is suitable for the sale time (about 27 hours) and a dose once a day. The bioavailability of desloratadine is proportional to the dose within 5 - 20 mg.

    Desloratadin is moderately linked to plasma proteins (83 - 87%). There is no evidence of clinical accumulation after taking a dose of 5 - 20 mg daily in 14 days.

    It is not known to be responsible for metabolism of desloratadin, so it has not completely excluded the interaction with some other drugs. Desloratadin does not inhibit CYP3A4 and CYP2D6 nor a substrate or inhibitor P - Glycoprotein.

    • Before taking Syrup Rinofil 2.5mg/5ml Abbott for allergic rhinitis (15ml)

    How to use

    Take oral use. Drugs can be taken with food or away from meals.

    Dosage

    Common dose of adults and children over 12 years: 5 mg (10 ml of syrup)/1 time/day.

    Note: In patients with liver and kidney dysfunction, the starting dose is recommended: 5 mg in Japan.

    Children are commonly used:

  • Children from 2 - 5 years old: 1.25 mg (2.5 ml)/1 time/day.

    • Children from 6 to 11 years old: 2.5 mg (5 ml)/1 time/day.

    Children from 6 months to 11 months of age: 1 mg (2 ml)/1 time/day.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? In case you suspect overdose, must go to the medical center immediately.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Rinofil Syrup 2.5 mg/5 ml you may experience unwanted effects (ADR).

    Common, ADR> 1/100

  • headache, sore throat (body pain, congestion, cough, dry or sore throat; fever; hoarseness; increase nasal secretion; difficulty swallowing, change voice).

    • Uncommon, 1/1000

  • Dizziness; dry mouth; dysmenorrhea; Gastrointestinal disorders (stomach acid, flatulence, heartburn, indigestion, stomach discomfort); tired; Muscle pain (pain or arthritis, muscle pain, crust, difficulty moving); asleep; Nausea.

    • Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Rinofil syrup 2.5 mg/5 ml contraindicated in the following cases:

    Patients with a history of hypersensitivity to desloratadine or loratadin or any ingredients of the drug.

    Be cautious when using

    notify your doctor if you have an allergic reaction when using desloratadin or with any other substance (food, color, etc.) or other drugs.

    Notify the doctor if you are pregnant or breastfeeding.

    For children: Safety and effectiveness of Desloratadin in children under 6 months of age has not been established.

    Notify the doctor if the symptoms do not improve after two days of treatment.

    Notice your doctor who is taking this medicine before you try allergies in the skin.

    Avoid drinking alcohol or medication to soothe the central nervous system (for example, tranquilizer, sleeping pills, antidepressants) during treatment.

    Notify your doctor if you have a history or if you have diseases: kidney disease, liver disease.

    The ability to drive and operate machinery

    For the recommended dose, this drug rarely causes drowsiness, reduces vigilance or obstructs the ability to drive trains and control machines.

    Pregnancy

    is not recommended unless there is a strict monitoring of a doctor.

    The period of breastfeeding

    is not recommended unless there is a strict monitoring of a doctor.

    Drug interaction

    is not related to drug interactions on clinical trials with erythromycin or ketoconazole when taken together. However, enzymes are responsible for the metabolism of desloratadin have not been recognized, and so some interactions with other drugs may not be completely excluded.

    In clinical pharmacokinetics research, drinking Desloratadin and alcohol does not increase the harmful effects of alcohol.

    Storage

    in a dry place, less than 30 ° C, avoid light.

    Other drugs

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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