Tatanol drugs relieve pain, reduce fever (10 blisters x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 10 blisters x 10 tablets
Ingredient Acetaminophen

Ingredient

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Composition information	Content
Acetaminophen	500mg

Uses

Indications

Tatanol drugs are indicated in the following cases:

The drug has analgesic effect, reduces fever from mild to medium.

Temporary pain relief in the treatment of pain caused by the flu, headache, sore throat, musculoskeletal aches, menstrual pain, toothache, migraine.

Pain relief mechanism: Prostaglandin synthesis inhibitors - Intermediate pain.

A reduction mechanism: Prostaglandin synthesis in the center of thermostatic thermostats in the hilly area causes peripheral vasodilation results to increase skin circulation through the skin, increase sweating, cool down. Tmax 1-3 hours. Extend time for 3-4 hours.

Quick distribution to all tissues. The ratio of binding to protein at the treatment dose is 10%. About 90 - 95% of the dose is metabolized in the liver mainly due to the combination of glucuronic acid, sulfate and cysteine. The metabolism is very fast and can be accumulated in case of overdose after the metabolic lines are mainly aging. When the drug is accumulated, it can be toxic to the liver and kidneys.

Semi -cancellation time T1/2 is about 1-4 hours. Elimination through urine is mainly in the form of combined.

Before taking Tatanol drugs relieve pain, reduce fever (10 blisters x 10 tablets)

How to use

Tatanol 500 medicine for oral use.

Dosage

Adults and children over 12 years 1 capsule/time x 2-3 times/day, distance of doses apart at least 4 hours apart. Do not use more than 8 tablets/day.

Children> 6 years: 1 tablet/time x 1 time/day. Do not use more than 4 tablets /day.

Do not use acetaminophen to treat pain for more than 10 days in adults or more than 5 days in children, unless guided by a physician.

Do not use acetaminophen for adults and children to treat high fever on their own (over 39.5 ° C), fever lasts for more than 3 days, or recurrent fever, unless due to a physician, because such a fever may be a sign of a severe disease that needs to be diagnosed quickly by a physician.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? These symptoms usually appear in the first 24 hours and may still occur after 2-4 days.

Treatment: Immediately transfer to the hospital, causing vomiting or gastric lavage to eliminate drinking drugs. Take activated carbon (activated carbon can reduce the effectiveness of treatment when taking acetylcysteine to treat overdose acetaminophen). Using N-acetylcystein specific antidote, the amount of N-acetylcystein is used depending on the amount of acetaminophen used. It is recommended to use N -acetylcystein immediately after overdose of acetaminophen, especially within 10 - 12 hours. Determine the concentration of acetaminophen at the latest after 4 hours.

Display in the case after 24 hours of overdose but not treated with N - Acetylcystein. Treatment to support total status, maintain water balance, electrolytes.

What to do when forgetting a dose?

If you are using the medication regularly, use the forgotten dose as soon as you remember. If the next regular dose period is, skip the forgotten dose and use the next dose as directed. Do not use additional medicine to compensate for the forgotten dose.

Side Effects

When using Tatanol, you may experience unwanted effects (ADR).

Skin rash and other allergic reactions occur. Usually the erythema or urticaria, but sometimes worse and accompanied by fever due to drugs and mucosal lesions. Patients with susceptibility to rare salicylate sensitive to acetaminophen and related drugs. In a few separate cases, acetaminophen has caused neutropenia, thrombocytopenia and hypoglycemia.

Uncommon, 1/1000

DA: Ban.

Stomach - intestines: Nausea, vomiting.

Hematology: Dehydration (neutropenia, reducing all bloody, leukopenia), anemia.

Kidney: Kidney disease, kidney toxicity when abusing for a long time.

Rare, ADR

Other: Hypersensitivity reaction.

Instructions on how to handle ADR

Notice the unwanted physician when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Tatanol drugs are contraindicated in the following cases:

Patients with hypersensitivity to the ingredients of the drug.

Patients with glucose-6-phosphate dehydrogenase deficiency.

Patients with anemia many times.

severe liver failure.

There is heart, lung, kidney disease.

Be cautious when using

should be cautious when using the drug in patients with severe renal impairment (CLCR

Consult your doctor if the symptoms last more than 10 days.

With acetaminophen, the doctor needs to warn the patient about the signs of serious skin reactions such as Steven-Jonhson syndrome (SJS), toxic skin necrosis syndrome (Ten) or Lyell syndrome, acute external pustular syndrome (AGEP).

The ability to drive and operate machinery

The drug does not affect driving and operating machinery.

Pregnancy

has not determined the safety of acetaminophen ding during pregnancy related to unwanted effects that may be available to the fetus. Therefore, only acetaminophen should only be used in pregnant people when needed.

Breastfeeding period

Research in mothers using acetaminophen after lactation, no unwanted effect in breastfeeding.

Medicinal interaction

long -term oral high doses of acetaminophen increases the anticoagulant effect of COUMARIN and indandion derivatives. This effect seems less or not clinically important, so acetaminophen is preferred than salicylate when it is necessary to relieve mild pain or reduce fever for patients who are using cooumarin or indandion.

Out of alcohol too much and long -term, increasing the risk of acetaminophen toxic to the liver.

Anti -convulsions (including Phenytoin, Barbiturat, Carbamazepin) that causes enzyme induction in the liver microsom, which can increase the toxicity of the liver.

Coordinate with toxic drugs on the liver increases the risk of toxicity on the liver.

It should be noted that the likelihood of serious antipyretics in patients used at the same time phenothiazine and cooling therapy.

Storage

In a dry, cool place (below 30 ° C). Avoid light.

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