Tazoretin topical gel to treat medium and mild acne (30g)

Dosage form Tube x 30g
Specifications Adapalene

Ingredient

Composition information	Content
Adapalene	0.1%

Uses

Indications

0.1% tazoretin drugs are indicated in cases of medium and mild acne treatment in adults and children over 12 years old.

Pharmacy

Pharmacological group: Acne treatment.

Code ATC: D10AD03

adapalen:

Adapalen is a retinoid compound that has been shown to have anti -inflammatory activity in vivo and in vitro; Adapalen is sustainable with oxygen, light and no chemical reaction. The mechanism of action of Adapalen, like tretinoin, is to cohesion to the specific retinoic acid receptors of the nucleus but different tretinoin is not attached to the protein of the receptor in the cytoplasm.

Adapalen when used on the skin has the effect of decomposing acne and also works on the abnormalities of the process of horny and differentiation of the epidermis, both of these cases are acne factors. The mechanism of action of adapalen is to normalize the differentiation of epithy cyst cells and thus reducing the formation of acne micro -acne.

pharmacokinetics

adapalen:

In humans, Adapalen is absorbed through poor skin; In clinical trials, the adapalen concentration in plasma is not found at a measured level when used long -term on a wide skin area with acne with analytical sensitivity level of 0.15 ng/mL. Therefore, it is not possible to identify the pharmacokinetic parameters about the bioavailability of adapalen when applying on the skin.

Before taking Tazoretin topical gel to treat medium and mild acne (30g)

How to use

Apply thin layer of tazoretin to the disease area after washing and dry.

Dosage

Apply 1 time/day in the evening before going to bed. Avoid gel wire in the eyes, lips, mucosa.

Safety and effectiveness of the drug has not been determined in children younger than 12 years old. Hence do not take medicine for children under 12 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

If the reaction signs appear when using an overdose of the drug, the patient needs to stop the drug immediately and send a report to the nearest medical facility, and then in the order there will be a collection of reports at the provincial medical facility. Or can report directly to the regional ADR center.

Symptomatic treatment for patients in this case.

What to do when you forget a dose? However, if close to the next use, skip and use the drug on time as planned. Note that it should not be used double the prescribed amount.

Side Effects

When using 0.1%tazoretin, you may experience unwanted effects (ADR).

Common, 1/10> ADR ≥ 1/100

Dry skin, skin irritation, burning sensation on the skin.

Contact dermatitis, uncomfortable feeling for the skin, itching, peeling, acne appears.

Unknown frequency

Allergic dermatitis, pain.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

and send reports to the nearest medical facility, and then in the order will have a collection of reports at the provincial health facility. Or can report directly to the regional ADR center.

Warnings

Contraindicated

Tazoretin 0.1% contraindicated drug in the following cases:

Hypersensitivity to Adapalen or any ingredients of the drug.

Caution when using

Avoid eye contact, lips, nose angle, mucosa. Do not apply the drug on the cut, scratched, the skin of eczema, sunburned skin. Avoid exposing strong light.

The ability to drive and operate machinery

Tazoretin does not affect the ability to drive and operate machinery.

Pregnancy

Contraindicated for pregnant women.

Breastfeeding period

Contraindications for breastfeeding women.

Medicinal interaction

Precautions when used with products that can cause elsewhere, sulfur, resorcinol or salicylic acid.

Storage

Store in closed packaging, avoid moisture, avoid light, temperature below 30⁰C.

Other drugs

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