Telfast BD 60mg film tablets reduce the effectiveness of allergy symptoms (3 blisters x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 3 blisters x 10 tablets
Ingredient Fexofenadin hydrochlorid

Ingredient

Composition information	Content
Fexofenadin hydrochlorid	60mg

Uses

indicated

Telfast BD appointed treatment in the following cases:

Allergic rhinitis: Telfast BD 60mg is indicated to treat seasonal allergic rhinitis in adults and children 12 years of age and older.

Chronic urticaria: Telfast BD 60mg is indicated to treat non -complicated skin symptoms of chronic urticaria in adults and children aged 12 and older. The drug reduces itching and the amount of urticaria in a significant way.

Pharmacokology

Fexofenadin is a second -generation antihistamine drug, with specific antagonistic and selective effects on peripheral H1 receptors.

Fexofenadin is a metabolic substance that is active of terfenadin but is no longer toxic to the heart due to not inhibiting potassium channels associated with myocardial cycles.

Fexofenadin has no significant effect on cholinergic or dopaminergic resistance and does not have the effect of inhibiting Alpha-1 receptor or beta adrenergic. At the treatment dose, Fexofenadin does not cause drowsiness or affects the central nervous system.

The drug has a fast and prolonged effect.

Pharmacokinetics

absorption

Fexofenadin is well absorbed when used orally and starts to work after drinking 60 minutes. The peak concentration in plasma is achieved after 2-3 hours. The simultaneous use of Fexofenadin with a high -fat diet reduces AUC and CMAX of Fexofenadin, respectively, 21% and 20% respectively.

Distribution

About 60 - 70% Fexofenadin binds to plasma proteins, mainly with albumin and Alpha -1 acid Glycoprotein. It is unclear whether the drug will be through the placenta or excreted into breast milk. Fexofenadin does not pass the brain barrier.

Metabolism

Fexofenadin is very smaller (about 5%, mainly in the intestinal mucosa. Only about 0.5 - 1.5% of the dose is metabolized in the liver thanks to the cytochrom P450 enzyme system into non -active substance).

Elimination

The average selling time of fexofenadin is about 14.4 hours, lasting longer (31 - 72%) in kidney failure people. The drug is eliminated in a constant form of about 80%, and 11% through urine.

Before taking Telfast BD 60mg film tablets reduce the effectiveness of allergy symptoms (3 blisters x 10 tablets)

How to use

oral medication with water and before meals. Do not take medicine with fruit juice (such as oranges, grapefruit, apples).

Dosage

Adults and children aged 12 and older: The recommended dose of Telfast BD is 1 tablet x 2 times daily.

Renal failure people: The recommended starting dose is 1 tablet 60mg per day.

Hepatic failure: No dose adjustment.

Elderly: No dose adjustment, except for renal function impairment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Clinical studies with a placebo shows the unwanted effect rate in the patient group using Fexofenadin is similar to the placebo group.

The unwanted effects of the drug are not affected by the dose, age, gender and race of the patient.

Common (1/100):

Neurological: Drowsiness (1.3 - 2.2%), Fatigue, headache, insomnia, dizziness. 1/100):

Mental: Fear, sleep disorders, nightmares.

Digestive: dry mouth, abdominal pain.

Skin: skin rash, urticaria, itching. It is unclear the frequency (not estimated from the existing data):

Cardiovascular: Increasing heart rate, suspense.

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

TelFast BD drugs contraindicated in the following cases:

Patients with a history of allergies to any ingredients of the drug.

Be cautious when using

need to be cautious and adjust the appropriate dose when using drugs for people with impaired renal function because the concentration of drugs in plasma increases due to prolonged semi -waste time.

Be careful when taking drugs for the elderly (over 65 years old) often has renal physiological impairment.

Safety and effectiveness of Telfast BD 60mg has not been evaluated in children under 12 years old.

Do not arbitrarily use other H1 antihistamine drugs while using fexofenadin.

It is necessary to stop fexofenadin at least 24 - 48 hours before conducting antigen tests in the skin.

Use fexofenadin to increase psoriasis.

Do not take the drug when expiry to print on the packaging.

Use drugs for women during pregnancy and lactation

Pregnant women

There is no complete research on pregnant women, so only use fexofenadin for pregnant women when the maternal benefits are superior to the risk of the fetus.

Women who are breastfeeding

It is not clear whether the drug is excreted in milk, so it is necessary to be cautious when using fexofenadin for women who are breastfeeding.

The effect of the drug on the ability to drive and operate machinery

Although the drug is less likely to be drowsy, it still needs to be cautious when driving or controlling machines requires alertness.

Drug interaction

erythromycin and ketoconazole increases the concentration of fexofenadin in plasma but does not change the QT interval. There is no difference in unwanted effects reported when these drugs are used individually or in combination.

Antacomicisted with aluminum and magnesi if used in the time with fexofenadin will reduce the absorption of the drug, so they must use these drugs about 2 hours apart.

There is no interaction between fexofenadin and omeprazol.

Fexofenadin concentration may be increased by Verapamil, p - glycoprotein inhibitors.

Fexofenadin may increase alcohol content, central nervous sedatives, anti -cholinergic substances. Using fexofenadin with alcohol because of the increased risk of sedation (sleep).

Fexofenadin may reduce the concentration of acetylcholininininiserase inhibitors (in the central nervous system), Betahistin.

Fexofenadin may be reduced by concentrations by acetylcholinininininiserase inhibitors (central nervous system), amphetamine, acid resistant, grapefruit juice, rifampin.

Fruit juice (oranges, grapefruit, apples) can reduce the bioavailability of fexofenadin to 36%.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.