Telfast Kids 30mg Sanofi medicine for allergic rhinitis, urticaria for children (1 blister x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 1 blister x 10 tablets
Ingredient Fexofenadin HCl
Indication Allergic rhinitis, urticaria, itching, stuffy nose

Ingredient

Thành phần cho 1 viên

Composition information	Content
Fexofenadin HCl	30mg

Uses

indications

Tipast Kids medicine for children from 6 to 11 years old is indicated in the following cases:

Treatment of seasonal allergic rhinitis.

Treatment of non -complicated skin manifestations of chronic urticaria. The drug reduces itching and the amount of urticaria in a significant way.

Pharmacokic

TelFast Kids drug contains active ingredient Fexofenadin - second -generation antihistamine drugs, with specific antagonistic and selective effects on peripheral H1 receptors.

Fexofenadin is a metabolic substance that is active of terfenadin but is no longer toxic to the heart due to not inhibiting potassium channels associated with myocardial cycles.

Fexofenadin has no significant effect on cholinergic or dopaminergic resistance and does not have the effect of inhibiting Alpha-1 receptor or beta adrenergic. At the treatment dose, Fexofenadin does not cause drowsiness or affects the central nervous system. The drug has a fast and prolonged effect.

pharmacokinetics

absorption:

Fexofenadin is well absorbed when used orally and starts to work after drinking 60 minutes. Peak concentration in plasma is achieved after 2-3 hours. The simultaneous use of Fexofenadin with a high -fat diet reduces AUC and CMAX of Fexofenadin, respectively, 21% and 20% respectively.

Distribution:

About 60-70% Fexofenadin binds to plasma proteins, mainly with albumin and Alpha-1 acid Glycoprotein. The drug does not pass through the brain blood barrier. It is unclear whether the drug is through the placenta or excretion in breast milk or not.

Metabolism:

Fexofenadin is very little metabolized (about 5%, mainly in the intestinal mucosa. Only about 0.5-1.5% of the dose is metabolized in the liver thanks to the cytochrom P450 enzyme system into non-active substances).

Era:

The drug is eliminated in the form of unchanged in feces of about 80%, and 11% through urine. The average selling time of fexofenadin is about 14.4 hours, longer (31-72%) in kidney failure.

Before taking Telfast Kids 30mg Sanofi medicine for allergic rhinitis, urticaria for children (1 blister x 10 tablets)

How to use

drugs used to drink with water and before meals. Do not take medicine with fruit juice (such as oranges, grapefruit, apples).

Dosage

Children from 6 to 11 years old: The recommended dose of Telfast Kids is 1 tablet/time x 2 times daily.

Children with kidney failure: The recommended starting dose is 1 tablet/ day.

Pediatric patients: No dose adjustment.

The effectiveness of fexofenadin on children under 6 years old has not been determined.

The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? However, drowsiness, dizziness, fatigue and dry mouth have been reported.

How to handle: Use conventional measures to remove the drug that has not been absorbed in the gastrointestinal tract. Treatment of symptoms and total status support. Dialysis reduces the concentration of drugs in the blood (1.7%). There is no specific antidote.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Telfast Kids eye drops, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Neurological: Drowsy, tired, headache, insomnia, dizziness.

digestive: nausea, indigestion.

Other: prone to viral infection (colds, flu), dysmenorrhea, susceptible to upper respiratory infections, itchy throat, cough, fever, otitis media, sinusitis, back pain.

Uncommon, 1/1000

Neurological: Fear, sleep disorders, nightmares.

digestion: dry mouth, abdominal pain.

Instructions on how to handle ADR:

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Telfast Kids is contraindicated in patients with a history of allergies to any component of the drug. Telfast Kids is not recommended for children under 6 years old because of the risk of holes.

Be cautious when using

need to be cautious and adjust the appropriate dose when using drugs for people with impaired renal function because the concentration of drugs in plasma increases due to prolonged semi -waste time.

Be careful when used for people with heart disease, because this drug can lead to tachycardia or abnormalities.

Do not arbitrarily use other H1 antihistamines when using fexofenadine due to the safety and effectiveness of fexofenadin that have not been assessed in children under 6 years old.

Discontinue fexofenadin at least 24-48 hours before conducting injection antigen tests. Use fexofenadin to increase psoriasis.

The ability to drive and operate machinery

no.

During pregnancy and breastfeeding

no.

Breastfeeding period

No.

Drug interaction

erythromycin and ketoconazole increases the concentration of fexofenadin in plasma but does not change the QT interval. There is no difference in unwanted effects reported when these drugs are used individually or in combination.

Aluminum and Magnesi antacids if used simultaneously with fexofenadin will reduce the absorption of the drug, so they must use these drugs about 2 hours apart.

Fexofenadin concentration may be increased by Verapamil, p-Glycoprotein inhibitors.

Fexofenadin may increase alcohol content, central -wandering agents, anti -cholinergic substances. Avoid using fexofenadin with alcohol because it increases the risk of sedation (sleep).

Fexofenadin can reduce the concentration of acetylcholoinesstase inhibitors (in the central nervous system), Betahistin.

Fexofenadin may be reduced by concentrations by acetylcholinininininiserase inhibitors (central nervous system), amphetamine, acid resistant, grapefruit juice, rifampin.

Fruit juice (oranges, grapefruit, apples) can reduce the bioavailability of fexofenadin to 36%.

Storage

Store in a dry place, avoid light, temperatures below 30 ºC.

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