Telma 20 Glenmark medicine for hypertension (1 blister x 10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Telmisartan

Ingredient

Composition information	Content
Telmisartan	20mg

Uses

indications

Telma drugs are indicated in the following cases:

Treatment Hypertension is idiopathic in adults. 2 has a target organ damage.

Telmisartan occupies Angiotensin II place with strong affinity at the cohesion position on the AT1 receptor, the receptor is responsible for all the known activities of Angiotensin II. Telmisartan does not show any partial transport activity at the AT1 receptor.

Dynamic pharmacokinetics

Telmisartan quickly absorbed although the absorption amount changes. Telmisartan's absolute bioavailability is about 50%.

During the period after 3 hours, plasma concentrations are similar whether Telmisartan is drinking when hungry or with food.

Telmisartan combines most of the plasma proteins (> 99.5%), mainly with albumin and alpha-1 acid Glycoprotein. The average integral is in a stable state of about 500 L. Telmisartan metabolized by a conjugated reaction with Glucuronid. Metabolic substances have no pharmacological effects.

Telmisartan is almost completely eliminated through feces, mostly in the formless form. The total amount of secretion through the urine is

Before taking Telma 20 Glenmark medicine for hypertension (1 blister x 10 tablets)

How to use

Telmisartan tablets are used through oral routes once a day and should be taken with water, can be the same or not with food.

Telmisartan should be stored in a closed vessel because the drug has a desiccant property. The pill should be used immediately after removing the blister.

Dosage

adults

Normal dose in treating idiopathic hypertension:

The usual effective dose is 40 mg once daily.

Some patients may be effective at the dose of 20 mg/day.

Common dose in cardiovascular disease prevention:

recommended dose is 80 mg once a day.

Not yet established Telma's safe and effective parameters for children and adolescents at the age of 18 and there is no specific recommendation.

Other objects

Patients with renal failure: Experience is limited to patients with severe renal impairment or dialysis. The initial dosage recommends less than 20 mg for these patients.

Patients with liver failure: Contraindicated in patients with severe liver failure. For patients with hepatic impairment from mild to medium, the dose must not exceed 40 mg once a day.

Elderly patients: No need to adjust the dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose? The most prominent symptoms of Telmisartan overdose are hypotension and tachycardia; Dizziness due to slow heart rate, increased serum creatinine and acute renal failure have also been reported.

Telmisartan cannot be removed by hemorrhage. Patients should be closely monitored and treated based on symptoms and supportive treatment.

Overdose management and time from swallow and the severity of symptoms.

Proposal measures include vomiting and/ or gastric lavage. Activated carbon can be helpful in treating overdose. The electrolyte in serum and creatinine should be monitored regularly. If hypotension occurs, patients need to be placed on their backs and salt quickly.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Telma medicine you may experience unwanted effects (ADR).

rarely, 1/1000

The less common side effects include:

Infections: The urinary tract includes cystitis, upper respiratory infections including sore throat and sinusitis.

Hematology: Anemia .

Metabolism: hyperkalemia.

Mental: Insomnia, depression .

nerve: unconscious.

ears and mesmerizing: Dizziness.

Cardiovascular: slow heart rate, hypotension, hypotension.

Respiratory: Difficulty breathing, cough.

digestive: abdominal pain, diarrhea, indigestion , flatulence, vomiting.

musculoskeletal: back pain, muscle spasm, muscle pain.

Kidney and urinary: renal failure including acute renal failure.

Body and on -site: chest pain, weakness (weak).

Testing: increased blood creatinine.

rare/very rare ADR

Very rare and rare side effects include:

Infection: Blood infection includes death.

Hematology: Incretion, platelets.

immune: Anaphylactic reaction, hypersensitivity.

Metabolism: Hypoglycemia (in diabetes patients).

Mental: Anxiety. Neurological: Drowsy. vision: vision disorders. Cardiovascular: Slow heart rate. Respiratory: interstitial lung disease. digestion: dry mouth, stomach discomfort, taste disorder. liver: Hepatic disorders/abnormal liver function.

musculoskeletal joints: joint pain, limb pain, tendon pain (symptoms like tendonitis).

Systemic and on -site: The disease is like influenza . Dermatology: Evaluation (also fatal), leech indigo ( Eczema ), Red rash, urticaria, drugs due to drugs, toxic skin rashes.

Testing: Hemoglobin decrease, hyperuricemia, hyper enzyme, increased creatin phosphokinase in the blood.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Telma drugs contraindicated in the following cases:

Hypersensitivity to any active ingredient or excipient of the drug.

The three months and the last three months of pregnancy.

Biliary obstruction disorders.

Severe liver failure.

Concentrated use of Telmisartan with products containing Aliskiren is contraindicated in patients with diabetes or renal failure (GFR

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Do not use telmisartan for patients with bile stasis, bile congestion disorders or severe liver failure because Telmisartan is almost excreted in bile.

Patients with hypertension due to kidney stenosis on both sides or stenosis on one side only function when using Telma is at risk of hypotension and severe kidney failure.

Telma used in patients with impaired renal function should periodically monitor serum and creatinin levels.

Symptomic hypotension, especially after the first Telmisartan dose may occur in patients with volume impairment and/or sodium due to strong diuretic treatment, limited salt in food, diarrhea, vomiting. These cases need to be treated or adjusted before using Telmisartan.

Simultaneous use of ACE inhibitors, Angiotensin II or Aliskiren receptor inhibitors increase the risk of hypotension, hyperkalemia and impaired renal function (including acute renal failure).

Patients with primary Aldosteron intense syndrome will usually not respond to antihypertensive drugs that are impacted through inhibition of the renin-analiotensin system. Therefore, it is not recommended to use Telmisartan.

Similar to other vasodilators, it is necessary to be careful when indicated in patients with aortic stenosis or mitral valve, or hypertrophic myocardial obstruction

In diabetics treated with insulin or diabetes, hypoglycemia may occur when treated with Telmisartan.

Telmisartan can cause hyperkalemia.

The tablet is very sensitive to moisture, so it is necessary to use the drug immediately after removing the blister.

The ability to drive and operate machinery

When driving or operating machinery, need to be cautious because dizziness or drowsiness can sometimes occur when using antihypertensive therapy like Telmisartan.

Pregnancy

should not use Angiotensin II receptor antagonistic drugs in the first three months of pregnancy. The use of Angiotensin II receptor drugs is contraindicated during the three months between and the last three months of pregnancy.

The period of breastfeeding

Because there is no information related to Telma's use during breastfeeding, Telma is not recommended and should be given priority to using alternative treatments with safe documents that have been better proven during breastfeeding, especially when raising a newborn or premature babies.

Drug interaction

drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Digoxin : Telmisartan increases the concentration of digoxin in plasma (49%)

heparin, immunosuppressive drugs (cyclosporin, tacrolimus) and trimethoprim , other-acting drugs on Renin-Anotensin-Aldosterone system, salt containing potassium, potassium diuretics, NSAIDs: High risk

Lithium: Telmisartan may increase the lithium concentration that has recovered in serum and toxicity that has been reported.

NSAID: may reduce the effect of lowering the hypotension of the Angiotensin II receptor antagonistic drug, and can lead to further decline in renal function.

Diuretics (thiazide or diuretic): Combined with Telmisartan can lead to loss of fluid loss and risk of hypotension.

Other antihypertensive drugs: Telmisartan's hypotension effect can be increased when used simultaneously.

corticosteroid (systemic line): Reducing the effect of hypotension.

Storage

Storage below 30 ° C. Avoid moisture and light.

Other drugs

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