Tenadinir Maxim medicine for mild and medium infections (1 blister x 10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Cefdinir

Ingredient

Composition informationContent
Cefdinir300mg

Uses

Indications

The treatment of infection is mild and moderate caused by the following sensitive bacteria strains:

Adults and children over 12 years old

pneumonia suffer from the community caused by the haemophilus influenzae strains, Haemophilus parainfluenzae, streptococcus pneumoniae, Moraxella Catatrhalis.

Chronic bronchitis is caused by strains of Haemophilus influenzae, Haemophilus parainfluenzae, Streptococcus pneumoniae, Moraxella Catatrhalis.

Sinusitis caused by strains of Haemophilus Influenzae, Streptococcus pneumoniae, Moraxella CatVrhalis.

Sore throat/tonsillitis is caused by streptococcus pyogenes.

Non -complicated dermatitis and tissue caused by staphylococcus aureus and streptococcus pyogenes.

For children from 6 months - 12 years old

Musical medicine is more suitable than capsules.

Pharmacokological

The mechanism of action of CEFDinir is to inhibit the synthesis of bacteria walls. Cefdinir has a broad spectral activity against Gram -positive and gram -negative microorganisms. Cefdinir works most on the in vitro and clinical bacteria such as:

Aerobic Gram-positive bacteria, including: Staphylococcus aureus (including the Beta-Lactamase seminarians), Streptococcus Pneumoniae (penicillin sensitive strain), Streptococcus pyogenes.

Aerobic gram-negative bacteria, including: Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella Catatrhalis (including beta-lactamase seminarians).

Cefdinir does not work on Pseudomonas, Entobacter Species, anti -methicilin -resistant saphylococci and anaerobic bacteria.

pharmacokinetic

absorption

CEFDINIR's peak plasma concentration is reached within 2 to 4 hours after drinking. Foods containing high fat content will reduce the absorption capacity of the drug from 16% to 10%. So do not use cefdinir with food.

Distribution

The average distribution of CEFDinir in adults is 0.35 l/kg. CEFDinir is connected to plasma about 60 - 70%, this cohesion does not depend on concentration. Cefdinir can be distributed into phlegm, tonsils, sinuses, mucous membranes, ear production, tissue in the mouth. Cefdinir does not see breast milk.

Metabolism

Cefdinir is not metabolized.

Elimination

Cefdinir is excreted mainly through the kidney with half -life of semi -excreted life of 1.7 hours. Cefdinir clearance in patients with renal function.

Before taking Tenadinir Maxim medicine for mild and medium infections (1 blister x 10 tablets)

How to use

Take oral use. Do not drink with cefdinir with food.

Dosage

Dosage for all infections is 600 mg/day/day and treatment within 10 days. There is no one -day -dose research for people with pneumonia and skin. So only drink 2 times/day in these patients.

Inflammation type
Dosage
Treatment time Dong 300mg every 12 hours 10 days

600mg every 24 hours

10 days

600mg every 24 hours

10 days

600mg every 24 hours

5 days or 10 days

Patients with renal failure

Adults

Creatinine clearance

Pediatric patients

Creatinine clearance

Patients with hemorrhage

Due to the hemorrhage excretion of cefdinir from the body, for patients with chronic separation, the starting dose is 300mg or a dose of 7mg/kg x 2 days once. After each hemolytic refinement, use 1 dose of 300mg or 7mg/kg/day x 2 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Signs and symptoms of poisoning after overdose with other beta lactam antibiotics include: nausea, vomiting, epigastric pain, outside and convulsions.

Cefdinir can be removed from the body through hemorrhage. In case of severe poisoning due to overdose, hemorrhage can help eliminate Cefdinir from the body. That may be useful in case of severe poisoning due to overdose use, especially if the renal function is impaired.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

No report.

Uncommon, 1/1000

No report.

Not determined frequency

Neurology: Stun, dizziness.

Body: Uncomfortable, sweating.

Digestive: diarrhea, abdominal pain, serious colitis, colitis with fake membranes manifested by blood stools, discomfort in the oral cavity, want to defecate.

Hearing: tinnitus.

The immune system: anaphylactic reactions such as shortness of breath, spreading burning, angioedema, urticaria.

Skin and subcutaneous tissue: Stevens-Johnson syndrome, Lyell syndrome.

Hematology: Obventage hypotension, grain leukemia, thrombocytopenia.

Respiratory system: interstitial pneumonia or pie syndrome, wheezing.

Kidney: acute renal failure .

Hepatitis system: Sudden hepatitis, liver dysfunction with a significant increase in AST (GOT), ALT (GPT) or alkaline phosphatase, jaundice.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

Tenadinir 300 drug contraindicated in the following cases:

Patients with allergies to cephalosporin antibiotics or any ingredients of the drug.

Do not use drugs for children under 6 months old.

Precautions when using

Caefdinir should be used with the following patients:

People with a history of hypersensitivity to the penicillin group.

Personal or family -tended people who have allergic reactions, such as bronchial asthma, rash or urticaria.

People with severe kidney disorders. Dosage should be reduced in patients with transient or long -lasting renal function (creatinine clearance

Patients who do not nourish oral or patients need to be nourished by vein or can be depressed (Cefdinir may reduce prothrombin time, so they need to be meticulously monitored in these subjects because they can develop symptoms of vitamin K).

Elderly patients: When using this drug for elderly patients, the dose and dosage distance should be adjusted, based on carefully clinical comments on the patient's state.

Other caution:

When doubtful or uncertain about infections or preventive indications, patients should not take the drug as it may increase the risk of developing bacteria against drugs.

As well as antibiotics with wide antibacterial spectrum, prolonged treatment can lead to the development of antibacterial strains. Must monitor patients carefully if necessary. If poisoning occurs during treatment, there should be appropriate supportive treatment.

Cefdinir should be used cautiously with patients with a history of colitis.

stool tinged with redness when drinking cefdinir and iron -containing preparations such as powdered milk or drinking with nutrients.

may have a reddish urine.

The ability to drive and operate machinery

There has been no full study of the effect of the drug on the ability to drive and operate machinery.

However, when using the medication may experience stun, dizziness, tinnitus should avoid driving or operating machinery if this symptom appears.

Pregnancy

There is no adequate and controlled study in pregnant women. Only use Cefdinir during pregnancy when really necessary.

Breastfeeding period

After using a single dose of 600mg, Cefdinir is not detected in breast milk. However, you should still be cautious when used for breastfeeding women, only used when really necessary.

Medicinal interaction

Antacids (containing aluminum or magnesium) simultaneously cefdinir with drugs containing aluminum or magnesium reduces CEFDINIR absorption. If Antacid is really necessary during treatment, it is necessary to take cefdinir before or after at least 2 hours to take antacid drugs.

Probenecid: Like other beta-lactam antibiotics, Probenecid inhibits the renal elimination for Cefdinir.

Iron supplements and iron -containing foods: Cefdinir simultaneous use with iron -containing substances or will reduce Cefdinir absorption. If you really need to add iron during the treatment, then you need to take Cefdinir at least before or after 2 hours.

Storage

Store in a cool dry place, at a temperature not exceeding 30 ° C, avoiding light.

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Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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