Terbiskin 1% Hasan skin cream treatment for skin fungal infections, tinea versicolor (15g)

Dosage form Box
Specifications Terbinafin hydrochlorid

Ingredient

Thành phần cho 1 tuýp

Composition information	Content
Terbinafin hydrochlorid	1%

Uses

Indications

The treatment of fungal infections in the skin caused by Trichophyton (such as T. rubrum, T. Mentagrophytes, T. Verrucosum, T. Violaceum), Microsporum Canis and Epidermophyton Flocosum.

Treatment of skin fungal infections caused by candidiasis (such as C. Albicans).

Treatment of tinea versicolor caused by Pityrosporum Orbiculare (also known as Malassezia Furfur).

Pharmacological

terbinafine is a broad -spectrum antifungal drug belonging to the Allylamine group. Terbinafin has the effect of killing fungi or mushroom pliers depending on the concentration of drugs and experimental mushrooms.

The drug has a fungal activity for many mushrooms, including skin fungus such as Trichophyton mentagophytes, T. rubrum, T. Verucosum, Microsporum Gypseum, M. Nanum, Epidermophyton Flocosum, fungi like Aspergillus, bipolar mushrooms like Blastomyces, Mold and Men as Candida Albicans, C. ParaLosis, C. ParaLosis, C. ParaLosis, C. ParaLosis Scopulariopsis Brevicaulis.

terbinafin affects the first phase in sterol biosynthesis in mushrooms, an important component of the fungal cell membrane, causing an ergostol deficiency and accumulating squalen in the cell, leading to the destruction of mushroom cells. Terbinafin works by inhibiting the enzyme Squalen Epoxidase in the fungal cell. This enzyme Squalen epoxidase is not associated with the Cytochrom P450 system.

pharmacokinetics

absorption:

The drug is absorbed into the body below 5% when applied on the spot.

Distribution:

The ratio of terbinafin is linked to high plasma proteins> 99%. The drug is distributed mainly on the horny layer of the skin, sebum, nails, toenails, hair with higher concentrations in plasma concentrations.

Metabolism:

The drug is metabolized in the liver into non -active substances.

Era:

The drug is excreted mainly in urine in the form of inactive metabolites. Selling duration of plasma is 17 - 36 hours in adults and 27 - 31 hours in children. The concentration of fungicide in nails and toenails is maintained for a few weeks after stopping treatment. The rate of excretion may change in people with liver disease or kidney disease.

Before taking Terbiskin 1% Hasan skin cream treatment for skin fungal infections, tinea versicolor (15g)

How to use

topical skin.

Wash and dry the infected skin before taking the drug.

Apply a thin layer of cream on the infected skin and surrounding areas.

In case of rubbing dermatitis (mammary gland, interstitial toe fingers, buttocks, groin) should be covered with thin gauze, especially at night.

Should use the drug at exact time during the day. Forgetting the medication can lead to re -infection.

Dosage

Adults

Use drugs 1-2 times/day during treatment.

Treatment time:

Systemic skin fungus, inguinal mushrooms: 1 - 2 weeks. If used irregularly or stop treating early treatment is at risk of recurrence. In case of use for more than 2 weeks without improving, it is necessary to confirm the initial diagnosis. Treatment period does not last more than 4 weeks.

Children

Experience using Terbinafin on the spot on children is limited, so it is not recommended to use drugs for children under 16 years old.

Elderly

There is no evidence that the difference in dosage and side effects compared to young patients.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? However, the case of an overdose may occur if swallowing a 30g of Terbiskin cream, equivalent to 300mg of Terbinafin hydrochloride, comparison with a 250mg tablet Terbinafin hydrochloride (oral dose in adults).

Symptoms of overdose: headache, nausea, epigastric pain and dizziness.

In case of emergency, it is necessary to stop the drug and immediately call the 115 emergency center or go to the nearest local medical station.

Terbinafin overdose treatment is mainly used to discharge drugs from the body and treat symptoms if necessary.

What to do when forgetting a dose? If close to the next dose time, skip the dose and continue as normal treatment. Note that it should not be used double the prescribed dose.

Side Effects

Common, ADR> 1/100

Skin: peeling skin, itching.

Uncommon, 1/1000

Skin damage, scales, skin pigmentation disorders, erythema, burning sensation.

Rare, ADR

Skin: Dry skin, contact dermatitis, eczema, increased risk of hidden fungal infections.

Eye: eye disorders.

Unknown frequency

Systemic: rash, immune system disorders.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

contraindicated

1% terbiskin drug is contraindicated in cases of sensitivity to any ingredient of the drug.

Be cautious when using

stop using Terbiskin if the skin is progressive. Be cautious when taking medication for patients with psoriasis or sensitive to antifungal drugs grouplamine.

Only use skin medicine.

Avoid contact with eyes, nose, mouth, mucosa as well as not orally or not used in the vagina. If the drug accidentally sticks to the right eye to wash the eyes immediately with clean water and flowing water.

Avoid wearing tight or covered clothes where the drug is used.

Do not use soap with acid pH if infected with candidiasis.

Terbiskin cream contains cetostearyl alcohol, which can cause local irritation like dermatitis.

The ability to drive and operate machinery

Terbiskin does not affect the ability to drive and operate machinery.

Pregnancy

There is no data on drug use in pregnant women. Should only be used for pregnant women if the benefits are superior to the risk.

Lactation period

terbinafin is excreted in milk so it is not used for women who are breastfeeding. Do not allow children to be exposed to the treatment area including breasts.

Interactive drug

There is no drug interactive with Terbiskin.

Storage

Store in a dry place, less than 300C, avoid light.

Hasan - Dermapharm Joint Venture Company is one of the leading enterprises in research, development, production and commercialization of specialized pharmaceuticals meeting European quality standards. The production field of the company includes: tablets, tablets, hard capsules, powder, nuggets, water medicine, ice cream, ointment, powder and nuggets containing antibiotics of cephalosporin group, powder and nuggets containing microorganisms.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.