The Akitykity-New 200mg Pharbaco oral fluid is sweet, orange, and eliminates helminths, larvae and eggs (2 packs x 1.5g)

Dosage form Powder mixed drink
Specifications 2 package box
Ingredient Albendazol

Ingredient

Thành phần cho 1.5g

Composition information	Content
Albendazol	200mg

Uses

Indications

Akitykity oral powder powder - New indicated in the following cases:

Infection of one type or many types of intestinal parasites such as roundworms, needle worms, hookworms, mine worms, hairworms, eulet worms, melon seeds (Hymenolepis Nana), Tapkin (Toenia Solium), Beef tapeworm (T. Saginata), Opisthorchis Viverrinist and O.Sinensis.

Albendazole is also effective on immigration larvae in the skin. The drug also works for tapeworm larvae with brain damage (neurocysticercosis). Abendazole is a drug chosen to treat cases of follicles that cannot be surgery, but the long -term benefit of this treatment must be further evaluated.

Pharmacokic

albendazole is a derivative of carbamat benzimidazol, in terms of structure related to Mebendazole. The main metabolic form of albendazol is Albendazol Sulfoxid still has the pharmacological effect of the drug. The drug has a broad -active spectrum on intestinal worms such as hookworms, mine worms, roundworms, needle worms, eelworms, hairworms, capillaria worms, twisted worms and migrant larvae in the muscle and skin, tapeworms and turbulent larvae at tissue.

albendazole is active in both adulthood and larvae of intestinal worms and killing eggs of roundworms and hair worms.

The mechanism of action of albendazole is similar to other benzimidazols. The drug is associated with the sub -parasites, thereby inhibiting the coincidence of the sub -sub -trailers into the minor minor microorganisms of the cytoplasm, which are essential for the normal activity of the parasitic cell.

Dynamic pharmacokinetics

In humans, after drinking, Albendazol is very absorbed very poorly (5%). Most anti -helminth effects occur in the intestine. To have the effect of tissue, high and long -term doses.

After taking a single dose of 400 mg of albendazol, the peak concentration of sulfoxid metabolites achieved in plasma is about 0.04 - 0.55 micrograms/ml after 1 to 4 hours. When used with fat foods, plasma concentrations increase to 2-4 times.

Albendazol Sulfoxid binds to protein in plasma up to 70%. When long -term use in the treatment of tapeworm, albendazol sulfoxid concentration in tapeworm fluid can reach about 20% of plasma concentrations.

Albendazol sulfoxid through the brain barrier and concentration in brain fluid - marrow equal to about 1/3 of the plasma concentration.

Albendazole is rapidly and completely oxidized, into a metabolic substance that still works, Albendazol Sulfoxid, then converted into a compound no longer acting, Albendazol Sulfon.

Albendazole has half -life eliminated from plasma for about 9 hours. Sulfoxid metabolites are eliminated by the kidneys along with sulfon metabolites and other metabolites. A negligible amount of sulfoxid metabolism is excreted through bile.

Before taking The Akitykity-New 200mg Pharbaco oral fluid is sweet, orange, and eliminates helminths, larvae and eggs (2 packs x 1.5g)

How to use

Cut the packet of drugs and pour the powder into the cup.

Pour water into the drug pack, then pour water from the package into the cup.

Stir and drink immediately.

Dosage

roundworm, needle worm, hookworm or hairworm

Children from 1 to 2 years old: 200 mg (1 pack), 1 single dose for 1 day. Drugs.

Adults: Take 400 mg, take 1 time, take 3 days.

Children: Take 5mg/kg/day, take 3 days.

Adults: Take 800 mg per day, for 28 days. Treatment may be repeated if necessary. Sometimes up to 2 or 3 treatments. Unexplained dosage.

Adults: 15 mg/kg/day for 30 days. Treatment can be repeated after 3 weeks.

Children: See adult dose.

Adults: Take 400mg/day/time for 3 days. Treatment can be repeated after 3 weeks. Treatment can be repeated after 3 weeks. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When treating for a short time (no more than 3 days) can see a few uncomfortable cases in the digestive tract (epigastric pain, melting) and headache.

In the treatment of tapeworms or tapeworm larvae with brain damage, harmful effects are more common and worse.

Usually unwanted effects are not severe and recover without treatment. Only stop treatment when leukopenia (0.7%) or there is an abnormal liver (3.8% in follicles).

Common, ADR

Body: Fever.

Systemic body: allergic reactions

Blood: granulocytosis, general hematuria, grain leukemia, thrombocytopenia.

Instructions on how to handle ADR:

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Akitykity - New contraindications powder in the following cases:

There is a history of hypersensitivity to benzimidazol compounds or the ingredients of the drug.

Be cautious when using

Patients with abnormal liver function before starting treatment with albendazole need to consider carefully because of the liver metabolic drug and see a few people with liver poisoning. Also need to be cautious with blood diseases.

Patients with rare genetic problems are galactose, fructose; Lapp lactase or sucrase - isomaltase; Or poor absorption of glucose-galactose should not use this drug.

In the composition of an aspartam -containing drug, containing phenylalanine radicals, which may be harmful to people with phenylketon.

The drug contains about 2.3 mg of sodium/dose. It is necessary to consider the use of drugs for patients who must control the sodium diet.

Use drugs for women during pregnancy and lactation

pregnancy:

Do not use albendazole for pregnant women except for cases of mandatory use without any other way. The patient must not be pregnant for at least a month after using albendazol. If the patient is taking the drug and if he is pregnant, he/she must stop the drug immediately and understand that the drug can cause serious danger to the fetus.

breastfeeding period:

Do not know how much the medicine is used for breast milk. Therefore, it is necessary to be very careful when using albendazol for nursing women.

The effect of the drug on the ability to drive and operate machinery

unknown effects of the drug.

Drug interaction

dexamethasone: The lowest stable concentration in the plasma of Albendazol Sulfoxid is about 50% higher when used in combination with 8mg of dexamethasone with each dose of albendazol (15 mg/kg/day).

Praziquantel: Praziquantel (40 mg/kg) increases the average concentration in plasma and area under the curve of Albendazol Sulfoxid about 50% compared to the single albendazole (400mg).

cimetidine: Albendazol sulfoxid concentration in bile and in the cystic fluid increased by about twice in people with follicles when used in combination with cimetidine (10 mg/kg/day) compared to using lone albedazol (20mg/kg/day).

Theophylin: The pharmacokinetics of theophylin (transmitted for 20 minutes theophylin 5.8 mg/mg) does not change after taking 1 albendazol (400 mg).

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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