Theralene Sanofi supports the treatment of allergic rhinitis symptoms, urticaria (40 tablets)

Dosage form Film bag tablets
Specifications Box of 2 blisters x 20 tablets
Ingredient Alimemazine

Ingredient

Composition information	Content
Alimemazine	5mg

Uses

indications

Theralene 5 drugs are indicated in the following cases:

Treatment in case of insomnia occasionally (for example, when traveling away) and/or transient (for example, when there is an emotional event).

Symptomatic treatment for allergies such as:

Rhinitis (for example, seasonal rhinitis, unintentional rhinitis ...);

Conjunctivitis (eye inflammation);

urticaria.

To reduce dry cough and cough due to irritation, especially when coughing in the afternoon or at night.

Pharmacology

Alimemazin: A phenothiazin has a string of fat wire and characterized by:

A clear sedative effect in the common dose due to histaminergic and central adrenolytic effects.

A anti -cholinergic effect causes peripheral side effects.

A peripheral adrenolytic effect may have hemodynamic effects (the risk of hypotension).

Through the competitive antagonism mechanism that can be reversed at different levels, all antihistamine drugs have the same ability to fight against the effects of histamine, especially on the skin, bronchial, intestinal and blood vessels.

Dynamic pharmacokinetics

There is no information about pharmacokinetics of alimemazin but the common characteristics of all antihistamines and especially phenothiazine, can be mentioned:

Absorption: Birth is usually not high.

Distribution: Large distribution volume by fat solubility.

Metabolism: capable of strong metabolism in some cases with the formation of many metabolites, thus explaining why a small amount of drugs found in urine in the form of unchanged.

Elimination: The semi -cancellation time changes but often long, should be suitable for medication once a day.

Before taking Theralene Sanofi supports the treatment of allergic rhinitis symptoms, urticaria (40 tablets)

How to use

Take oral use. Take pills with some water.

Time to take medicine: Because the drug has the effect of drowsiness, it is best to start treating allergies in the evening.

Treatment time: Short -term symptoms should only be treated (a few days). If coughing, should only take the drug at times of cough.

Dosage

antihistamine resistance, anti -cough: drink repeated many times a day in case of need, but not more than 4 times a day.

Adults: 1-2 tablets at a time.

Children over 6 years old (ie 20 kg): 0.125 to 0.25 mg/kg/time, or 1/2 - 1 capsule at a time.

Effects on sleep: Take once at bedtime.

Adults: 5 to 20 mg, 1 to 4 capsules.

Children over 6 years old: 0.25 to 0.5 mg/kg, ie:

Children from 20 to 40 kg (6 to 10 years old): 1 tablet

Children from 40 to 50 kg (10 to 15 years old): 2 tablets Should start treatment at lower dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Signs of Alimemazin overdose:

Convulsions (especially in children), perceived disorders, coma, drowsiness, hypotension, heart rate increased, changing heart electrical and lower body heat. This syndrome includes symptoms of body temperature, muscle spasms, mental changes and automatic nervous system activity. Because this syndrome is at risk of death, stopping the drug and contacting the doctor immediately. Take the next dose next time, usually as prescribed by the doctor.

Side Effects

When using Theralene 5 you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: tired, drowsy.

nerve: headache, dizziness.

digestive: dry mouth, dense phlegm

Uncommon, 1/1000

Eyes: Eye regulatory disorders

digestion: constipation Urinary: Urinary retention

Rare, ADR

Blood: loss of granulocytes, leukopenia.

Circulation: Hypotension, reduction of heart rate.

Liver: jaundice due to cholestasis. nerve: Symptoms of foreign tower, Parkinson's disease, restlessness, acute muscle disorders, late movement disorders, dry mouth, epilepsy.

Respiratory risk: The risk of respiratory arrest, even death in children.

Unknown frequency

Cardiovascular: arrhythmia, atrial tachycardia, atrial - ventricular disorder, ventricular tachycardia, ventricular.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Theralene 5 contraindications in the following cases:

Hypersensitivity to any ingredients of the drug.

History of allergies to antihistamines (phenothiazines).

People with liver or kidney dysfunction, epilepsy, Parkinson's disease, hypothyroidism, adrenal medulla, myasthenia gravis.

Overdose due to Barbituric, Opiate and Alcohol.

Patients with coma or have used a large amount of central neuronal drugs.

Children under 6 years old (due to inappropriate formation).

History of granulocytes (significantly reducing the number of white blood cells) with other phenothiazin.

Difficulties due to prostate causes or other causes.

Some glaucoma (glaucoma).

Be cautious when using

Usually do not use this medication in the following cases, unless the doctor's prescription:

In the first three months of pregnancy.

during breastfeeding.

Use in combination with sultopride.

The drug can cause heartbeat disruptive. Be careful when taking this medication in patients with heart disease.

In the case of a fever that appears or persists, there are or not accompanied by signs of infection (sore throat ...), pale or sweaty, should immediately notify the treating doctor.

Allergy manifestations:

This drug is used within the framework of allergic symptoms. Therefore, it is best to search for allergies. If symptoms persist or get worse, the doctor must consult.

ho:

Do not use this medication to treat coughs. In this case, cough is a natural self -defense vehicle needed to eliminate bronchial secretions. If coughing has talks, accompanied by congestion, fever, should consult a doctor.

In the case of chronic (long -term) bronchial or lungs accompanied by a cough, it is necessary to consult a doctor.

Do not combine with bronchodilator thinner (dragon phlegm, mucus pills).

Insomnia:

In children, it is necessary to consult a doctor when children have sleep disorders. If possible, should find the cause of insomnia. If the insomnia persists more than 5 days, consult your doctor.

Be cautious when used

Do not use alcoholic or alcoholic drinks during treatment. The sun should be avoided during treatment.

Elderly: Easy to reduce blood pressure, fainting, confusion and foreign symptoms.

Patients with epilepsy, asthma, stomach ulcer.

This drug contains lactose, this is a sugar. In case the patient does not tolerate a few types of sugar, notify the doctor before taking this medication.

The ability to drive and operate machinery

should pay attention to the possibility of drowsiness when using this drug, especially for drivers and operators.

Pregnancy

should not take this drug for the first three months of pregnancy.

Can take the drug in the three months or the last three months of pregnancy, provided that it is only used for a short time (a few days) and with the recommended dose.

However, at the end of pregnancy, if this drug is abused, it can lead to adverse effects on babies. Therefore, always consult a doctor before taking the drug and never be overdosed.

The period of breastfeeding

This drug is very easy to produce breast milk. Because the drug is sedative, can affect children (sleep, reduce tone) or on the contrary, irritation (insomnia), should not use this drug in the case of breastfeeding.

Interactive drug

alcohol: Alcohol increases the sedative effects of antihistamine drugs. The disadvantage on alertness can be dangerous when driving and using machinery. Avoid using alcoholic beverages and alcoholic drugs.

Sultopride: The risk of ventricular arrhythmia, especially torsion, due to the drug with physiological effects.

The coordinates need to consider:

Other central nervous system inhibitors (Anti -sedative drugs, barbiturat, benzodiazepine, clonidin and substances, sleeping pills, morphine derivatives (analgesic and anti -cough), methadone, nerve drugs, anxiety antidote): increase the central nervous inhibition activity. The effect of alertness can become dangerous when driving or using machines.

Atropine and other substances are active like atropine (antidepressants, imipramine, anti -cholinergic drugs, Atropin -type anti -spasms, disopyramids, nerve drugs they phenothiazine): Increasing unwanted effects like Audin like urinary, constipation, dry mouth.

To avoid possible interactions between multiple drugs, it is necessary to tell the doctor or pharmacist about all other drugs you are taking.

Storage

Store drugs in dry places, avoid light, temperature not exceeding 30 ° C.

Other drugs

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