Thylmedi 16mg Mediplantex anti -inflammatory, anti -allergic drug (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Methylprednisolone

Ingredient

Composition information	Content
Methylprednisolone	16mg

Uses

Indications

Thylmedi 16mg pills are indicated in the following cases:

Methylprednisolon is indicated in nonspecific therapy that requires anti -inflammatory and immunodeficiency effects of glucocorticoid for: rheumatoid arthritis, systemic lupus erythematosus, some temporal vasculitis and artery inflammation, sarcoid disease, bronchial asthma, chronic ulcerative, blood -soluble anemia, oxygen and merciless diseases include betrespave.

Pharmacy

methylprednisolon is a glucocorticoid, derivative 6 - Alpha - methyl of Prednisolon has anti -inflammatory, anti -allergic and immune -inhibited effects.

pharmacokinetics

The bioavailability of the drug is about 80%, after taking 1-2 hours the plasma concentration reaches the maximum, the effect time lasts about 12 hours. Methylprednisolon is metabolized in the liver and excreted through urine. The sale time of the drug is about 3 hours.

Before taking Thylmedi 16mg Mediplantex anti -inflammatory, anti -allergic drug (3 blisters x 10 tablets)

How to use

Take the tablet with water.

Dosage

Determine the dose for individuals. In the issuing indications, Glucocorticoids should be used at the lowest doses and in the shortest time of clinical effect.

Use a single dose of the day that causes less unwanted effects than the doses of split. When you need a large dose for a long time, you should apply a single daily -time therapy, use a single dose every 2 days in the morning.

Monitoring and periodic assessment of osteoporosis parameters, hemorrhage, glucose tolerance, eye effects and blood pressure.

Peptic ulcer prophylaxis with H2 - histamine anti -receptor drugs when high doses.

Long -term treatment with glucocorticoid needs additional calcium to prevent osteoporosis.

Treatment of acute asthma attacks:

32 - 48mg/day, for 5 days, then the additional treatment with lower dose in 1 week, when the acute hit is reduced faster.

Severe diseases:

At first, methylprednisolon usually used 0.8mg/kg/day divided into small doses, then reinforced treatment for a single daily dose, followed by a minimum reduction to the minimum dosage.

rheumatoid arthritis:

The dose started 4mg/day. During the higher dosage period: 16 - 32mg/day, then gradually decreases quickly.

Severe ulcerative ulcerative ulcerative:

8 - 24mg/day.

Nephromatic kidney syndrome:

Start the dose of 0.8 - 1.6mg/kg for 6 weeks, then gradually reduce the dose for 6 - 8 weeks.

Immune hemolytic hemolytic anemia:

Take 64mg/day for 3 days, then gradually reduce the dose for 6-8 weeks.

Sarcoid disease:

0.8mg/kg/day to improve the disease, then use the maintenance dose 8mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Cushing syndrome, muscle weakness and osteoporosis.

When using too high doses for a long time may occur inhibiting the adrenal gland and increasing the adrenal gland energy.

Management:

Reduce the dose step by step instead of stopping suddenly. Need to consult the doctor.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as the prescribed dose

Side Effects

When using Thylmedi 16mg, you may experience unwanted effects (ADR).

The most common unwanted effects occur when high -dose and long -term use.

Common, ADR> 1/100:

Insomnia, nervousness is prone to excitement, increased appetite, indigestion, hair, diabetes, joint pain, cataracts, glaucoma, nosebleeds.

Dizziness, convulsions, psychosis, fake tumors in the brain, headache, mood change, delirium, hallucinations, refreshment; edema, hypertension; acne, skin atrophy; Cushing syndrome; Inhibiting the pituitary -adrenal gland, slow growth, glucose intolerance, hypokalemia, alkaline infection, amenorrhea, sodium and water, hyperlem of blood glucose; Stomach ulcers, nausea, vomiting, bloating, esophageal ulcer, pancreatitis; muscle weakness, osteoporosis, fracture; Hypersensitivity reaction.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Thylmedi pills 16mg contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

Severe infections, except for bacterial shock and meningitis.

Viral, mushroom or tuberculosis skin lesions.

using a living virus vaccine.

Precautions when using

Caution for people with osteoporosis, new people connecting blood vessels, mental disorders, stomach ulcers, duodenal ulcers, heart failure, diabetes, hypertension, adult children, elderly people, pregnant women.

Acute adrenal failure may occur when stopping the drug suddenly after a long time of treatment or when stressed.

When using high doses can affect the effects of vaccine vaccine.

The ability to drive and operate machinery

Do not take medicine.

Pregnancy

For extension of body corticosteroids for mothers can lead to mitigation of babies' weight. Need to use caution.

Breastfeeding period

No contraindications.

Drug interaction

methylprednisolon is a cytochrome P450 enzyme induction and is the substrate of the P450 3A enzyme, so this drug affects the metabolism of cyclosporine, erythromycin, phenobarbital, phenytoin, carbamazide Rifampicin.

Phenytoin, Phenobarbital, Rifampicin and diuretics decreased potassium can reduce the effectiveness of methylprednisolon.

methylprednisolon may cause hyperlemor of blood glucose, so higher insulin dose is needed.

Storage

In a dry place, avoid light, temperature below 30 ° C.

1958 - 1960, establishing a Southern Medicine Company - Central Medicine, is a state -owned enterprise under the Ministry of Health. 1961 - 1970, renamed the pharmaceutical company level 1. 1991 - 2004, transformed into the Central Pharmaceutical Company I. 2005-2010, the company performed the period of equitization and transformation from state -owned enterprises into joint stock companies and changed its name to MEDIPLANTEX Central Pharmaceutical Joint Stock Company.

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