Thylmedi 4mg Mediplantex anti -inflammatory and anti -allergic drug (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Methylprednisolone

Ingredient

Composition information	Content
Methylprednisolone	4mg

Uses

Indications

Thylmedi 4mg Mediplantex 3x10 drug is indicated in the following cases:

Methyl Prednisolon is indicated in nonspecific therapy that requires anti -inflammatory and immunosuppressive effects of glucocorticoids for rheumatoid arthritis, systemic erythematosus lupus, some forms of inflammation, temporal artery and artery inflammation, sarcoid disease, bronchial asthma, chronic ulcerative, hemolytic anemia, granular hypoithuria and severe beginths include betrespave.

Methyl Prednisolon also has indications in the treatment of nephropathy syndrome.

Pharmacokology

Methyl Prednisolon is a glucocorticoid, 6-alpha-methyl derivative of prednisolon that has anti-inflammatory, anti-allergic and immunosuppressive effects.

pharmacokinetics

The bioavailability of the drug is about 80%, after taking 1-2 hours the plasma concentration reaches the maximum, the duration of effect lasts for about 12 hours. Methyl Prednisolon is metabolized in the liver and excreted through urine. The sale time of the drug is about 3 hours.

Before taking Thylmedi 4mg Mediplantex anti -inflammatory and anti -allergic drug (3 blisters x 10 tablets)

How to use

Take oral use.

Dosage

Determine the dose for individuals. In the issuing indications, glucocorticoids should be used at the lowest doses and in the shortest time of clinical effect. Using a single dose of the day causes less unwanted effects than the doses of split. When a large dose is needed for a long time, apply a daily -way therapy, use a single dose every two days, in the morning.

Monitor and periodically evaluate the parameters of osteoporosis, hemorrhage, glucose tolerance, eye effects and blood pressure.

Peptic ulcer prophylaxis with H2-Histamine anti-receptors when taking high doses.

Long -term treatment with glucocorticoid needs additional calcium to prevent osteoporosis.

Treatment of acute asthma attacks

Use 32 - 48mg/day, for 5 days, then additional treatment at a lower dose for 1 week, when the acute acute faster decreases.

Severe diseases

At first, methylprednisolon usually used 0.8mg/kg/day divided into small doses, then reinforced treatment for a single daily dose, followed by gradually reduced to the minimum dosage to work.

rheumatoid arthritis

The dose started 4mg/day. During the dosage higher than 16 - 32mg/day, then gradually decreases.

Severe ulcerative colon ulcer

Use 8 - 24mg/day.

Nephropathy syndrome

Start the dose of 0.8 - 1.6mg/kg for 6 weeks, then gradually reduce the dose for 6-8 weeks.

Immune hemolyticemia

Take 64mg/day, in 3 days then reduce the dose gradually for 6 - 8 weeks.

Sarcoid disease

Use 0.8mg/kg/day used to remain the disease, then use the maintenance dose 8mg/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

When using too high doses for a long time may occur inhibiting adrenal glands and increasing the energy of the kidney gland.

Handling

Must reduce the dose step by step instead of stopping suddenly. Need to consult a doctor.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Thylmedi 4mg Mediplantex 3x10, you may experience unwanted effects (ADR).

The most common unwanted effects occur when high -dose and long -term use.

Common, ADR> 1/100

Insomnia, nervousness is easily agitated, increased appetite, indigestion, him, diabetes, joint pain, cataracts, glocoma, nosebleeds.

Uncommon, 1/1000

Dizziness, convulsions, mental disorders, fake tumors in the brain, headache, mood changes, delirium, hallucinations, refreshment, edema, hypertension, acne, skin atrophy, Cushing syndrome: Inhibit the anomalous pituitary axis, slow growth slowly, non -tolerance of glucose, reduce potassium blood, alkaline infections, sterile, keep sodium and water, increase glucose.

Stomach ulcers, nausea, vomiting, bloating, esophageal ulcer, hypersensitivity reaction. Pancreatitis, muscle weakness, osteoporosis, fracture.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Thylmedi 4mg Mediplantex 3x10 drug is contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

Severe infections, except for bacterial shock and meningitis.

Viral, mushroom or tuberculosis skin lesions.

using a living virus vaccine.

Caution when using

Caution for people with osteoporosis, new blood vessels, mental disorders, stomach ulcers, duodenal ulcers, heart failure, diabetes, hypertension, adult children, elderly people, pregnant women.

Acute adrenal failure may occur when the drug is stopped suddenly after a long time of treatment or when stressed.

When using high doses can affect the effects of vaccine vaccine.

The ability to drive and operate machinery

Do not take medicine.

Pregnancy

For extension of body corticosteroids for mothers can lead to mitigation of babies' weight. Need to use caution.

Breastfeeding period

No contraindications.

Drug interaction

methylprednisolon is a cytochrome P450 enzyme induction and is the substrate of the P450 3A enzyme, so this drug affects the metabolism of cyclosporine, erythromycin, phenobarbital, phenytoin, carbamazide Rifampicin.

Phenytoin, Phenobarbital, Rifampicin and diuretics decreased blood potassium can reduce the effectiveness of methylprednisolon.

methylprednisolon may cause hyperlemor of blood glucose, so higher insulin dose is needed.

Storage

In a dry place, avoid light, temperature below 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.