Ticoldex Danapha eye drops treat keratitis, conjunctivitis (5ml)

Dosage form Bottle x 5ml
Specifications Dexamethasone sodium phosphate, chloramfenicol, excipients just enough

Ingredient

Composition information	Content
Dexamethasone sodium phosphate	5mg
Chloramfenicol	20mg
August excipients just enough	5ml

Uses

Indications

Ticoldex Danapha 5ml drug is indicated in the following cases:

Conjunctivitis caused by infections or complications.

Unpaladed keratitis.

deadlocked and bacterial infections in the rules.

Surveying before and after eye surgery. Dexamethasone has a stronger anti -inflammatory effect than hydrocortisone (about 25: 1) and Prednisolon (about 5: 1).

chloramphenicol

is a broad spectrum antibiotic that works on both gram (-) and gram (+), the mechanism of operation is attached to the ribosom of bacteria and inhibiting protein biosynthesis at the early stage of bacteria. Chloramphenicol is effective for eye-causing bacteria in the eye: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, beta-haemolytic streptococci, Haemophilius Influenze, Moraxella Catacrhalis, Neisseria Gonorrhoeea. However, there may be resistance to chloramphenicol in these species, so it is necessary to rely on local drug resistance information or sensitive testing for drugs.

Chloramphenicol does not work for Entobacteriaceae and Pseudomonas Aeruginosa.

pharmacokinetics

dexamethason

After small eyes, the drug is absorbed into the aquarium, cornea, iris, veins, retina. The whole body absorption occurs but only meaning when at high doses. The drug is mainly distributed in the liver and kidneys. Dexamethasone sodium phosphate quickly converted into dexamethasone during circulation. Up to 77 % dexamethasone associated with albumin. The average half -life of dexamethasone is 3.6 ± 0.9 hours. Kidney elimination drugs.

chloramphenicol

After small eyes, the drug is absorbed into the aquarium, from which appears in the circulatory system. Chloramphenicol is found in the cerebrospinal fluid, saliva and the highest concentration concentrated in the liver and kidneys. Chloramphenicol also passed the placenta fence and into M sữa milk.

chloramphenicol is excreted mainly in the urine in the form of glucuronic complex and a small part of excretion through bile and feces. The half -life is 1.5 - 5 hours, increasing in patients with liver and infants from 24 - 28 hours.

Before taking Ticoldex Danapha eye drops treat keratitis, conjunctivitis (5ml)

How to use

Small eyes.

Dosage

Use as directed by the doctor or according to the following average dose:

Put in the eye 1-2 drops/time. Date many times. Treatment period must not exceed 10 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? If irritated, pain, swelling occur after small eyes, should wash the eyes for 15 minutes. If the symptoms are still there, it is necessary to reconsider treatment.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Ticoldex Danapha 5ml, you may experience unwanted effects (ADR).

Can cause temporary stimulation on the spot: discomfort, tearing, burning, conjunctiva conjunctiva.

can cause skin -conjunctiva sensitive reactions.

When used for a long time: glaucoma due to corticosteroids, cataracts, surface conjunctivitis, thin cornea layer, bead.

In case of corneal or edges, corticosteroids may slow scars and cause superinfection.

Chloramphenicol can cause myeloma syndrome.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Ticoldex Danapha 5ml contraindicated in the following cases:

People allergic to one of the ingredients of the drug.

corneal herpes.

Eye fungal disease.

glaucoma.

infants.

People with proliferate anemia.

Caution when using

is only used in the case of essential in infections due to sensitivity to chloramphenicol, not in combination with an eye drops containing other antibiotics or sulfamid.

If used for long -term treatment, the glaucoma and clarity must be monitored.

The drug contains thiomersal as preservatives, so it can cause some allergic reactions. Please inform your doctor if any allergies occur.

The ability to drive and operate machinery

does not affect the ability to drive, operate machinery. However, after small eyes and eyes are temporarily blurred or visual disorders, it is necessary to wait until the vision is clear before driving, operating machinery.

Pregnancy

There is no report on the effects of pregnant women when taking eye drops for dexamethasone and chloramphenicol. However, the drug can cross the placenta fence, so avoid ticoldex during pregnancy.

Breastfeeding period

chloramphenicol into breast milk, so if the mother takes medication, she should stop breastfeeding.

Drug interaction

Avoid using Ticoldex with other antibiotic -containing eye tracers or sulfamids.

Should notify the doctor for treatment of all the drugs being used before taking any other drug.

Storage

In a dry place, avoid light, the temperature does not exceed 30 ° C.

Do not take the drug more than 30 days after opening.

Do not use overdue drugs on the box, or drugs with suspicion of quality such as opaque, strange objects, mold. Do not overdose specified.

Read the instructions carefully before use. If you need more information about the drug, please consult your doctor or pharmacist.

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Disclaimer

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