Tinidazol 500 DHG drug prophylaxis after surgery (10 blisters x 10 tablets)
Dosage form Box of 10 blisters x 10 tablets
Specifications Tinidazole
Ingredient
| Composition information | Content |
| Tinidazole | 500mg |
Uses
Indications
Tinidazol 500 drug is indicated in the following cases:
Preventive infection after surgery due to anaerobic bacteria, especially infections related to colon, stomach and gynecological surgery.
Treatment of anaerobic bacteria infections such as:
Gynecological infections: endometritis, endometritis, hose abscess. Blood infection. Skin infections and soft tissues. Upper and lower respiratory infections: pneumonia, pleural pleura, lung abscess. Non -specific vaginitis. Trichomonas infection of urinary genitals both men and women. Tinidazol is an imidazol conductor, which works with both virgin animals and mandatory anaerobic bacteria such as Bacteroides spp., Clostridium spp. microorganisms and then destroy the DNA chain or inhibit the synthesis of DNA. Tinidazol has the effect of preventing and treating bile or gastrointestinal infections, treatment of abscess and anaerobic infections such as necrotic balancing and vapor gangrene. Tinidazole is absorbed most after drinking, the sale time is 12-14 hours. Tinidazol is widely distributed and concentrations achieved in bile, milk, cerebrospinal fluid, saliva and other tissues in the body are similar to plasma concentrations, the drug is easy through the placenta. Only 12% attached to plasma proteins. The drug has not metabolized and the metabolites of the drug are excreted in the urine and a less part in the feces. Pharmacokology
pharmacokinetics
Before taking Tinidazol 500 DHG drug prophylaxis after surgery (10 blisters x 10 tablets)
How to use
Take for oral after meals.
Dosage
Prevention of infections after surgery
Adults
Take the only dose 2 hours before surgery 12 hours.
Anaerobic infection treatment
Adults
Take 2g first day, then take 1g daily or 500mg x 2 times/day. Treatment for 5-6 days is sufficient, but the treatment time depends on clinical results; Especially in some difficult positions to eliminate infections, it is necessary to prolong treatment for more than 7 days.
Non -specific vaginitis
Adults
Take a single dose of 2g. Treatment for two consecutive days with a dose of 2g once a day (a total dose of 4G) effectively cured faster.
acute ulcerative ulcer
Adults
single dose 2g.
Urinary genital infection
Adults
Take a single dose of 2g. At the same time need the same treatment for both partners (spouse).
Children
Take the only dose 50 - 70mg/kg body weight. Can use a dose repeat, if necessary.
Giardia infection
Adults
single dose 2g.
Children
Take the only dose 50 - 75mg/kg body weight. Can use a dose repeat, if necessary.
amoeba infection in the intestine
Adults only take 2g dose, for 2-3 days.
Children take the only dose of 50 - 60mg/kg body weight per day, for 3 consecutive days.
liver amoeba
Adults
The total dose varies from 4.5g to 12g, depending on the level of harmful effects of Entamoeba histolytica. With the liver amoeba, it may be necessary to combine pus with tinidazol treatment. Start taken 1.5 - 2g, once a day, for 3 days. Sometimes 3 -day treatment is not effective, it takes up to 6 days.
Children
Take the only dose 50 - 60mg/kg body weight per day, for 5 consecutive days.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose? Mainly treat symptoms and support. Stomach lavage. It is possible to eliminate Tinidazol easily by the cup.
Side Effects
When using Tinidazol 500, you may experience unwanted effects (ADR).
CommonLess
When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Tinidazole 500 contraindicated drug in the following cases:
Be cautious when using
during treatment with Tinidazol should not use alcohol preparations because there may be the same reaction as Disulfiram (flushed, abdominal spasms, vomiting, fast heartbeat).
The ability to drive and operate machinery
Caution when driving and operating machinery.
Pregnancy
Tinidazole easily passes through the placenta, does not take this medication for pregnant women, especially in the first 3 months of pregnancy. There is no evidence Tinidazole is harmful in the later period of pregnancy, but it is necessary to consider the benefits of medication and the possibilities that are harmful to the fetus and the mother.
Breastfeeding period
Tinidazol excreted through breast milk, should not be used for mothers who are breastfeeding or only breastfeeding at least after 3 days of stopping the drug.
Medicinal interaction
cimetidine can reduce the elimination of Tinidazol from the body due to cimetidine inhibits the metabolism of Tinidazol in the liver, so it increases both treatment and toxic effects.
rifampicin may increase the release of Tinidazol due to increased metabolism of Tinidazol in the liver, so it reduces the treatment effect.
Storage
In a dry place, the temperature does not exceed 30 ° C, avoiding light.
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