Tirokoon 100mg HuteCs medicine for gastric contractions (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Tiropramide

Ingredient

Composition informationContent
Tiropramide100mg

Uses

indications

Tirokoon drug is indicated in the following cases:

  • Indications for treatment of gastric contractions, irritable syndrome. Uterine spasms such as menstruation, threatening miscarriage, uterine spasms. The drug has little effect on vascular smooth muscles.

    Tiropramid's anti -spasm mechanism: Tiropramid increases intracellular camp concentration because the drug activates the Camp synthesis. The increase in Camp leads to smooth muscle relaxation and prevent calcium flow through the membrane. Tiropramid isolated calcium in the sinuses of intracellular cells due to stimulating the cohesion of Ca ++ ions into the mechanical mesh system. Tiropramid also inhibits the absorption and release of Ca ++ ions.

    In contrast to papaverin, Tiropramid is not a phosphodiesterase inhibitor. Therefore, the impact mechanism of Tiropramid is completely different from the impact mechanism of papaverin on the smooth muscle. Tiropramid has a very low affinity for Calmodulin. The anti -spasm of smooth muscle spasm of Tiropramid does not depend on Calmodulin.

    Dynamic pharmacokinetics

    After the dose, the concentration of tiropramid in plasma is found after about 18 - 27 minutes. The peak concentration is about 1-1.7 hours and the sale time is about 2.34 - 2.61 hours. Tiropramid and some of its metabolites can be detected in urine by liquid chromatography within 24 hours after drinking.

    • Before taking Tirokoon 100mg HuteCs medicine for gastric contractions (10 blisters x 10 tablets)

    How to use

    oral medication. Can be taken with or not with food.

    Dosage

    Adults and children over 12 years old

    1 tablet (100 mg) at a time, 2-3 times/day.

    Children under 12 years old

    Not determined safety and effectiveness.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    If an overdose is needed to treat symptoms and support treatment.

    What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

    Side Effects

    When using Tirokoon, you may experience unwanted effects (ADR).

    Rare, ADR

  • Digestive: Nausea, vomiting, constipation.
  • allergies: Red, itching.

    • Other: dry mouth, thirst.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    Tirokoon drugs contraindicated in the following cases:

  • Hypersensitivity to Tiropramid or any ingredients of the drug.

    • The gastrointestinal stenosis.

  • Endectomy.
  • severe liver failure.
  • 12 -year -old children, nursing women.

    • Be cautious when using

    Precautions when used for pregnant women. Only used when really necessary and must be consulted by a specialist.

    Should use caution in people with glaucoma, prostate hypertrophy.

    If the allergic reaction is detected (erythema, itching), stop immediately.

    Tiropramid may interact with antihypertensive drugs, increasing the lowering effects of calcium channel blockers, so it is necessary to be cautious when coordinated.

    The ability to drive and operate machinery

    The drug does not affect the ability to drive and operate machinery.

    Pregnancy

    Precautions when used for pregnant women. Only used when really necessary and must be consulted by a specialist.

    The period of breastfeeding

    It is unclear whether the tiropramid will excrete in breast milk or not. Therefore, do not use for nursing women or must stop breastfeeding if taking the drug.

    Interactive drug

    tiropramid may interact with antihypertensive drugs, increasing the antihypertensive effect of calcium channel blockers, so it should be cautious when coordinated.

    Storage

    Store in closed packaging, temperatures below 30 ° C, avoiding light and moisture.

    Other drugs

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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