Tobcol eye drops 3-2 treatment of eyelid inflammation, conjunctivitis (5ml)

Dosage form Bottle x 5ml
Specifications Tobramycin

Ingredient

Thành phần cho 5ml

Composition information	Content
Tobramycin	15mg

Uses

Indications

5ml tobcol drugs are indicated for use in cases of infections caused by bacteria sensitive to Tobramycin such as: eyelid inflammation, conjunctivitis, tear bag inflammation, keratitis ....

Pharmacokological

Tobramycin is an aminoglycoside antibiotic obtained from the streptomyces tenebrarius culture medium.

The drug has a bactericidal effect. Although the exact acting mechanism is unknown, perhaps the protein synthesis inhibitors in sensitive bacteria by attaching it is not reversible to the 30S subunit of ribosom.

Effective spectrum: In general, Tobramycin works with many aerobic Gram -negative bacteria and some aerobic Gram -positive bacteria. The drug does not work with chlamydia, mushrooms, viruses and most anaerobic bacteria.

In vitro, toobramycin are usually inferior to gentamicin for some Gram -negative bacteria including E. Coli and Serratia. But Tobramycin is a bit stronger than Gentamicin for P. Aeruginosa which is sensitive to both drugs.

But in Vietnam the sensitivity of this bacterium for the drug has changed. In Vietnam Tobramycin works well with S. Typhi, especially in the South (100%), S. Flexner (95%), Proteus spp (98%).

According to ASTS data in 1999, bacteria increased to Tobramycin resistance including E.coli toboli resistant tobramycin with a rate of 27.8%, Entramycin anti -Tobramycin anti -tobramycin and Pseudomonas Aeruginosa resistant tobramycin at 46.1%.

There is a cross -resistance between tobramycin and gentamicin but there are about 10% of the gentamicin strains that are also sensitive to tobramycin. Because of the potential toxicity to the ears and kidneys, it is necessary to closely monitor the function of kidney, hearing and vestibular.

Dynamic pharmacokinetics

Popular drugs through the mucosa.

Before taking Tobcol eye drops 3-2 treatment of eyelid inflammation, conjunctivitis (5ml)

How to use

Tobcol 5ml solution Small use for the eye area.

Dosage

The usual dose: Put 1 drop into the conjunctiva, every 4 hours when the infection is mild and medium.

with severe, small infections in the conjunctiva 1 drop, every 1 hour.

Continue treatment until supporting, then reduce the number of small times.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Treatment: If overdose and adverse effects, use physiological saline solution to wash the eyes. Call the doctor immediately, or if the patient shows signs of overdose such as respiratory failure, call the emergency center 115.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Due to poorly absorbed drugs through the mucosa, unwanted effects are often:

Toxic and hypersensitivity reactions: itching, swelling of the eyelids and conjunctiva.

ears: Poison with vestibular and snail, especially in patients with impaired renal function.

Instructions on how to handle ADR:

Notice immediately to the doctor or pharmacist the harmful reactions encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Small Tobcol Eye solution is contraindicated in the case of patients sensitive to any component of the drug.

Be cautious when using

should not use the drug for a long time because it can cause bacteria that are not sensitive to tobramycin.

Be cautious when used for pregnant and lactating women.

The ability to drive and operate machinery

Persons who often drive or operate machinery should use drugs?

The drug does not affect the ability to drive and operate machinery.

Pregnancy

Women during pregnancy should take medicine?

Women during pregnancy should be cautious when using.

Breastfeeding period

Should women in breastfeeding should take medicine?

Women who are breastfeeding should be cautious when using.

Drug interaction

drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Like Gentamicin, if used simultaneously or followed by other substances that cause hearing and kidney toxicity, can increase the toxicity of aminoglycosides.

Concomitance use tobramycin with nerve -muscle blockers will be nervous - muscle and respiratory paralysis.

Using beta-lactam antibiotics (penicillin and cephalosporin) with tobramycin can cause significant mutual loss.

Storage

Leave a cool dry place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Other drugs

Disclaimer

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