Tocemux treatments for mucus, respiratory diseases with phlegm (10 blisters x 10 tablets)

Dosage form Hard capsules
Specifications Box of 10 blisters x 10 tablets
Ingredient Acetylcysteine

Ingredient

Composition information	Content
Acetylcysteine	200mg

Uses

Indications

Tocemux drugs are indicated in the following cases:

Used as a mucus in mucus (mucoviscidosis) (pancreatic fibrosis), respiratory diseases with mucus mucus like in acute and chronic bronchitis, and regular cleaning in trachea.

Pharmacokological

Acetylcystein (N - Acetylcystein) is the N - Acetyl derivative of L - Cystein, a natural amino - acid. Acetylcysteine is used as a mucus and antidote when the paracetamol overdose. The drug reduces the mucus in pus or not by separating the disulfide bridge in mucoprotein and facilitates the expansion of the cough, drainage or by mechanical methods.

Acetylcystein is used to protect the liver toxicity due to paracetamol overdose, by maintaining or restoring the liver's glutathion concentration, which is essential to cause the active active ingredient of paracetamol toxicity to the liver. In the overdose of paracetamol, a large amount of this metabolic substance is created because the main metabolic line (Glucuronid and Sulfate) becomes saturated. Acetylcystein converts into cystein stimulating glutathion synthesis and therefore, acetylcysteine can protect the liver if they start treatment within 12 hours after paracetamol overdose. Start treatment as soon as possible.

pharmacokinetics

After drinking, Acetylcystein is quickly absorbed in the digestive tract and acetyl reducing liver into cysteine and then metabolized. Achieving plasma peaks between 0.5 to 1 hour after taking the dose of 200 to 600 mg. Biological use when drinking low and may be due to metabolism in the intestinal wall and initial metabolism in the liver. Kidney clearance can account for 30% of the whole body clearance.

After drinking, the last half of the total acetylcysteine is 6.25 hours.

Before taking Tocemux treatments for mucus, respiratory diseases with phlegm (10 blisters x 10 tablets)

How to use

Tocemux drugs are taken orally.

Dosage

Make mucus pills

Adults and children ≥ 7 years: take 1 capsule/time, 3 times a day.

Children from 2 to 6 years old: take 1 tablet/time, 2 times a day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Other symptoms include respiratory failure, hemolysis, scattered blood clotting and renal failure. The death occurs in an overdose of acetylcystein during the treatment of paracetamol poisoning.

Symptomatic overdose treatment.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using tocemux drugs, you may experience unwanted effects (ADR).

Acetylcysteine has a large safety limit. Although rarely clinically bronchospasm in clinical due to acetylcysteine, it can still occur with all types of drugs containing Acetylcystein.

Common, ADR> 1/100

Digestive: Nausea, vomiting.

Cardiovascular: flushed, edema, fast heartbeat.

Neurological: Sleep, headache, tinnitus.

Respiratory: stomatitis, runny nose, snoring.

skin: rash, urticaria.

Rare, ADR

Systemic: Bronchospasm with the response of the whole body, fever, and cold.

Instructions on how to handle ADR

Using diluted acetylcystein solution can reduce the possibility of a lot of drugs. Hydrocortison or 125 mg of methylprednisolon.

can inhibit the hypersensitivity reaction with acetylcysteine including body rash, itching, nausea, vomiting, dizziness, using antihistamine first. There is an idea that hypersensitivity is due to an allergic mechanism on the basis of histamine release rather than the immunity. Because the hypersensitivity reaction has occurred 3% of acetylcysteine intravenous people to treat paracetamol overdose, physicians should pay attention to use antihistamine to prevent that reaction.

Note: Notify the doctor the unwanted effects encountered when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Tocemux drugs contraindicated in the following cases:

History of asthma (risk of bronchospasm with all types of drugs containing acetylcysteine).

hypersensitively to acetylcystein.

Children under 2 years old.

Caution when using

must closely monitor patients at risk of asthma, if using acetylcysteine for people with a history of allergies; If there is bronchodial spasm, bronchodilator spraying must be used such as salbutamol (beta-2- adrenergic selective, compartment effect) or ipratropium (antacistic drugs) and must stop acetylcysteine immediately.

When treated with acetylcystein, there may be a lot of diluted phlegm in the bronchi, need to be smoked to remove if the patient reduces cough.

The ability to drive and operate machinery

The drug does not cause drowsiness, so it can be used for car operators.

Pregnancy

There are no independent and controlled studies when using acetylcysteine for pregnant women, the drug is only used during pregnancy when really necessary.

Breastfeeding period

Safe drug for breastfeeding.

Medicinal interaction

acetylcysteine is a reducing agent that is not suitable for oxygen - chemicals.

Do not simultaneously use other cough pills or any drugs that reduce bronchial secretion during acetylcysteine treatment.

Storage

In a cool dry place, temperatures below 30 ° C, avoid light.

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