Transamin olic drugs treat leukemia, anemia (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Acid Tranexamic

Ingredient

Composition information	Content
Acid Tranexamic	250mg

Uses

Indications

Transamin medicine are indicated in the following cases:

Treatment of trend of bleeding due to increased body fibrin in the following cases: leukemia, anemia, hemorrhage, abnormal bleeding during or after surgery.

Pharmacokology

Plasmin resistance effect:

Tranexamic Acid is strongly attached to the Lysine link position (LBS), a affinity position with fibrin of plasmin and plasminogen, and inhibits the link of plasmin and plasminogen on fibrin. Therefore, the decomposition by plasmin is strongly inhibited. With the presence of plasmin resistance such as α2 - macroglobulin, in plasma, fibrin resistance effect of Tranexamic acid is also enhanced.

Hemostatic effect:

excessive plasmin causes platelet capacitors, the decomposition of blood clotting agents, etc., but even a slight increase also makes the specific degeneration of Fibrin occur first. Therefore, in cases of normal bleeding, the presence of tranexamic acid produces hemostasis by eliminating that fibrin decomposition.

pharmacokinetic

absorption

Blood concentration at a dose of 250 mg and 500 mg tranexamic acid is given by oral paths for healthy adults, reaching the highest concentration of 3.9 g/ml (for a dose of 250 mg) and 6.0 PG/ml (for a dose of 500 mg) 2 - 3 hours after taken. Biological destruction time is 3.1 hours and 3.3 hours respectively.

Elimination

When giving 500 mg of tranexamic acid through the oral route for healthy adults, the level of elimination through urinary tract is 30 - 52% 24 hours after taking the drug.

Before taking Transamin olic drugs treat leukemia, anemia (10 blisters x 10 tablets)

How to use

Transamin drugs are taken orally.

Dosage

Dosage for oral adults: 750 to 2000 mg tranexamic acid/day. Divided into 3 or 4 times. The patient's age and symptom adjustment should be adjusted.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? The overdose symptoms may be: nausea, vomiting, symptoms and/or hypotension.
There is no special measure to treat Tranexamic acid poisoning. If the poisoning is overdosed, causing vomiting, gastric lavage and active carbon. In both cases of oral and infusion, it is advisable to maintain additional fluids to promote the excretion of the kidneys and use symptomatic treatments and support treatment.
What to do when forgetting 1 dose?

Not recorded.

Side Effects

When using Transamin, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Stomach - intestines: anorexia, nausea, vomiting, diarrhea, heartburn.

Sensitive: itching, rash.

Nervous system: Sleep.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Transamin drugs contraindicated in the following cases:

Patients with thrombosis.

Patients with a history of hypersensitivity to any ingredients of the drug.

Caution when using

Caution in patients with thrombosis (brain thrombosis, myocardial infarction, thrombosis ... and in patients with possible thrombotic patients.

Patients with medical coagulation disease (simultaneously used with heparin, ...)

Postoperative patients, motionless patients and patients are bandaged.

Dosage reduction in patients with severe renal failure.

Used for children and chronic patients without any data on safety.

Elderly people have decreased physiological functions, so there should be measures to reduce the dose with careful supervision.

The ability to drive and operate machinery

Very rare cases of drowsiness occurs, however, for safety, be careful when driving and operating machinery.

Pregnancy

Clinical experience from treatment for pregnant women is limited. So far, clinical and research data shows no increased risk. Because the data is limited, the use, for pregnant women is only allowed when it is strictly indicated and when other treatment measures cannot be implemented.

Breastfeeding period

Transamin goes into breast milk but the risk of side effects in children is still not sure in the dose. Usually, the usual dosage can be used for breastfeeding women when necessary.

Medicinal interaction

Contraindications for drug coordination:

thrombin: can cause thrombosis.

Precautions when combining drugs:

estrogen and other hemostasis, blood clotting drugs: causing thrombosis.

Storage

Storage below 30 ° C.

Other drugs

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