Trinopast 75 OPV anti -epilepsy (2 blisters x 7 tablets)

Dosage form Box of 2 blisters x 7 tablets
Specifications Pregabalin

Ingredient

Composition information	Content
Pregabalin	75mg

Uses

indications

trinopast drug are indicated in the following cases:

Treatment of local seizures attached or not included in the whole secondary. The voltage in the central nervous system. Pregabalin reduces the release of neurotransmitters such as glutamat, noradrenalin ...

Pregabalin increases the concentration of gamma-aminobutyric acid (GABA) in nerve cells by increasing the activity of glutamic decarboxylase acid enzymes depending on the dose. Glutamic decarboxylase acid makes a enzyme that helps convert neurotransmitters stimulating glutamate to inhibitors. Therefore, pregabalin is more active than benzodiazepin, barbiturates and other depression.

Dynamic pharmacokinetics

Pregabalin is quickly absorbed after oral oral concentration achieved within 1.5 hours. Oral bioavailability reaches 90%. The condition and stability of the drug in the body achieved after 1 to 2 days.

Pregabalin is not linked to plasma proteins and insignificant metabolism. About 98% of the drug excreted in the urine in the form of unchanged substances. The average selling time is 6.3 hours.

Before taking Trinopast 75 OPV anti -epilepsy (2 blisters x 7 tablets)

How to use

Dosage daily is divided into 2-3 times. The drug can be taken during or outside the meal.

Dosage

epilepsy

The starting dose of 150 mg daily. Depending on the response of each patient and tolerance, the dose may increase to 300 mg/day after about 1 week, and if necessary, the dose can increase 600 mg/day after about 2 weeks.

Disseminated anxiety disorders

The starting dose of 150 mg daily. Depending on the response of each patient and tolerance, the dose may increase by 150 mg/day after the period of weeks of treatment until the maximum dose of 600 mg/day.

Neurological pain

The starting dose of 150 mg daily. Depending on the response of each patient and tolerance, after a period of 3-7 days, the dose may increase to 300 mg/day and after about 7 days of the next treatment, can increase to 600 mg/day.

Pain

The starting dose of 150 mg daily. Depending on the response of each patient and tolerance, the dose may increase to 300 mg/day after 7 days and if necessary, the dose of 450 mg/day can be increased.

kidney failure

What is the dose depends on the kidney function.

Creatinine clearance (CLCR) (ml/min)

Total daily Pregabalin dose (mg/day)*

How to divide the dose

Dosage after 1 week

Dosage after 2 weeks

Maximum dosage

≥ 60

150

300

450

600

2 - 3 times/day

30 - 60

150

225

300

2 - 3 times/day

15 - 30

25 - 50

100 - 150

150

1 - 2 times/day

25 - 50

50 - 75

1 time/day

No dose adjustment, except for kidney function damage.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

Sleep, confused, agitated, restless.

How to handle

There is no specific antidote, can use supportive treatments or dialysis when necessary.

What to do when you forget 1 dose? If it is nearly time to take the next dose, skip the forgotten dose and take medicine at the next recommended dose. Do not take double dose to compensate for the forgotten dose.

Side Effects

When using trionopast , you may experience unwanted effects (ADR).

Dizziness and drowsiness.

Other common side effects such as blurred vision, double look, appetite and weight gain, dry mouth, constipation, vomiting, bloating, refreshing, confusion, reducing sexual desire, erectile dysfunction , instability, dizziness, loss of air conditioning, tremor, linguistic, abnormal, fatigue and edema.

may have concentrated disorders, memory disorders, coordinated disorders and awkward gait.

Instructions on how to handle ADR

Notify the doctor with unexpected effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

trionopast contraindicated in cases of sensitivity to any component of the drug.

Be cautious when used

Caution with known brain diseases, lactose intolerance, impaired gastrointestinal function, congestive heart failure, diabetes patients.

The ability to drive and operate machinery

The drug is likely to cause dizziness and drowsiness, so do not drive and operate machinery.

Pregnancy

only use pregabalin during pregnancy when the benefits are superior to the hazardous fetus.

The period of breastfeeding

consult a doctor before using the drug.

Drug interaction

Concomitance Pregabalin with pioglitazon, Rosiglitazon may be the cause of weight gain and water retention.

Storage

Store at temperatures below 30 ° C, in a dry place.

Other drugs

Disclaimer

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