Trixlazi davipharm drugs supplement calcium, magnesi, zinc and vitamin D3 (3 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 3 blisters x 10 tablets
Ingredient Calcium carbonate, magnesium hydroxide, zinc sulfate, cholecalciferol
Indication Pregnancy, calcium deficiency, rickets
Contraindication Hyper calcium, hyper calcium, drug allergies

Ingredient

Composition information	Content
Calcium Carbonate	400mg
Magnesium hydroxide	150mg
Zinc Sulfate	5mg
Cholecalciferol	100UI

Uses

Indications

Trixlazi drugs are indicated in the following cases:

Use supplements with calcium, magnesium, zinc and vitamin D3 in diet, in mineral shortages.

Special recommendations in calcium, magnesium, zinc and vitamin D3 deficiency:

During menopause and postmenopausal.

Oral calcium is used to treat chronic blood calcium and calcium deficiency.

Hypacentia occurs in the following cases: chronic hypothyroidism and fake hypothyroidism, bone puree, rickets, chronic kidney failure, lower blood calcium due to anti -convulsed drugs, or when vitamin D deficiency.

Lack of calcium occurs when the daily diet does not provide enough calcium, especially in girls and the elderly, women before and after menopause and teenagers. Due to increased demand for calcium, children and women are the most risky.

Hypical calcium reduction causes evidence: convulsions, tetani, behavioral disorders and personality, growth retardation and brain growth retardation, bone deformation, most common are rickets in children and bone puree in adults.

Magnesi

Magnesi is a trace element that is important for health, along with calcium, magnesium working together in many body functions. If there is not enough magnesium, calcium will not be added to the bone.

zinc

Zinc is an essential trace element of the body in many enzymes. A serious zinc deficiency can cause skin damage, diarrhea; Increased risk of infection and developmental retardation in children. Symptoms of zinc deficiency include loss of taste and smell, slow healing wounds.

Vitamin D3

Participate in bone formation: Vitamin D3 plays a very important role in the process of bone formation thanks to the effect of metabolism of inorganic substances, mainly calcium and phosphate. Vitamin D3 increases the absorption of calcium and phosphate in the intestine, increases the reabsorption of calcium in the nearby tube, participating in the growth of growth of cartilage. So vitamin D3 is essential for the normal development of children.

During vitamin D3 deficiency, the intestines do not absorb enough calcium and phosphorus to reduce blood calcium, when the calcium is mobilized from the bone to stabilize blood calcium concentration, resulting in a child who grows slowly, rickets, bow legs, slow -hearted, and slow. Adults will have osteoporosis, bone porous, sparse bones. Pregnant women who lack vitamin D3 can produce babies with disabilities in the bone.

pharmacokinetic pharmacokinetics

calcium carbonate

The intestinal absorption in the intestine is inversely proportional to the amount of calcium eaten, so when a low -calcium diet will lead to increased compensation, partly due to the effects of vitamin D. After use, the amount of calcium ions discharged in the urine is the amount filtered in the glomerular and the amount of reabsorption. The reabsorption in the renal tubules is very effective because more than 98% of calcium ionic ions are filtered through the renal crane is reabsorbed into the bloodstream. The reabsorption efficiency is the main regulatory regulatory by the hypotheses and is also affected by the purification of Na+, the presence of non -reabsorbing anions and diuretic benefits.

The diuretics on the upward branch of the Henle straps increase the urinary calcium. In contrast, only the diuretics are not attached to the excretion of Na+ and Ca2+, resulting in reduced calciumuria. Armor hormone always regulates blood calcium ionic concentration by acting on the renal tubules. Calcium is only affected by calcium diet in normal people. A significant amount of calcium is deducted from milk during breastfeeding, a part of sweat and stool.

Magnesi Hydroxyd

When taken into the stomach will form Magnesi Chloride, then Magnesi Chloride is absorbed and then eliminated through urine in people with normal renal function.

zinc sulphat

Zinc is absorbed from the gastrointestinal tract and distributed throughout the body. The highest concentration in hair, eyes, female reproductive organs. The lower concentration is present in the liver, kidneys and muscles. 80% in blood found in red blood cells. Zinc concentration in plasma is from 70 - 110 ng/ dL and about 50% of this amount is closely linked to albumin. About 7% of amino acid binding and the other part attached to A-2-Macroglobulin and other proteins.

Vitamin D3

Vitamin D3 is absorbed in the intestinal mucosa thanks to bile salt and lipid, accumulated in the liver, fat, bones, muscles and intestinal mucosa, excreted mainly through bile ducts in a small part. The drug is linked to plasma α-globulin. In the body, vitamin D3 metabolizes in the liver and kidneys that produce an active metabolite of 1.25-dihydroxychololeciferol thanks to the enzyme hydroxylase. Vitamin D3 is excreted mainly through feces, a small part of urine excretion, the sale time is 19 - 48 hours.

Before taking Trixlazi davipharm drugs supplement calcium, magnesi, zinc and vitamin D3 (3 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

2 capsules per day (or 1 tablet x 2 times daily), used before meals.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Blood calcium concentration exceeds 2.6 mmol/l (10.5 mg/100 ml) is considered to be hypercalcemia. Stop using calcium will be able to address mild hypercalcemia in patients without clinical symptoms and normal kidney function.

When blood calcium concentration exceeds 2.9 mmol/l (12 mg/100 ml) must immediately use the following measures:

Intravenous compensation by sodium chloride intravenously. For forced diuretic in Furosemid or ethacrynic acid to increase calcium and sodium excretion when using too many 0.9%sodium chloride solutions.

Monitor the concentration of potassium and magnesium in the blood and replace blood early to prevent complications in treatment.

Monkey monitors and can use β-commenergic blockers to prevent heavy arrhythmia.

Can hemogle, can use calcitonin and adrenocorticoid during treatment.

Determine blood calcium concentration in a certain period of time regularly for orientation for treatment.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Trixlazi, you may experience unwanted effects (ADR).

Rare, 1/10,000

Digestive: constipation.

Systemic: sweating, flushed face, low blood pressure.

Instructions on how to handle ADR:

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Trixlazi drugs contraindicated for the following cases:

Patients with hypersensitivity to any ingredients of the drug.

Related to calcium carbonate: ventricular vibration in cardiovauca resuscitation; heart disease and kidney disease; hypercalcemia; malignant bone destruction; severe calcium and osteoporosis due to motionless; Patients are using digitalis (because of the risk of Digitalis poisoning).

Precautions when used

Caution in cases of mild calcium hypercalcium, chronic kidney failure or symptoms of calcium accumulation in the kidney. Should monitor calcium levels in urine.

To be out of reach of children.

The ability to drive and operate machinery

No report.

Pregnancy

No harm when taking daily doses of daily needs.

Breastfeeding period

Drug interaction

The following drugs inhibit calcium excretion through the kidneys: thiazid, clopamid, ciprofloxacin, chlorthalidon, anti -convulsions.

Calcium reduces the absorption of Demeclocyclin, Doxycyclin, metacyclin, minocyclin, oxytetracyclin, tetracyclin, enoxacin, fleroxacin, levofloxacin, lomefloxacin, norfloxacin, ofloxacin, pefloxacin, iron, iron, iron, iron, and other substances.

Calcium increases the toxicity of the heart of glycosides digitalis because increased blood calcium levels will increase the inhibition effect of Na+-K+-Aatpase of the cardiacid.

glucocorticoid, phenytoin reduces the absorption of calcium through the gastrointestinal tract. Diet with phytat, oxalate reduces calcium absorption because it forms difficult complexes to absorb.

Do not use it simultaneously with cholestyramin or colestipol hydrochloride, as it can lead to reducing the absorption of vitamin D3 in the intestine.

Do not simultaneously use with phenobarbital and or phenytoin because these drugs can reduce the concentration of 25-hydrogengocalciferol and 25-hydroxy-cecalciferol in plasma and increase vitamin D3 into non-active substances.

Do not use simultaneously with corticosteroids because of the effect of Vitamin D3.

Storage

In a dry place, avoid light, the temperature does not exceed 30 ° C.

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