Tyrosur Engelhard is treated and prevented with infections (5g)
Dosage form Gel
Specifications Tube x 5g
Ingredient Tyrothricin
Indication Atopic dermatitis, contact dermatitis, arm tear
Ingredient
| Composition information | Content |
| Tyrothricin | 1mg/g |
Uses
indications
Tyrosur gel is indicated in the following cases:
Treatment and prevention of infections for small wounds on the surface of the skin is or at risk of bacterial superinfection sensitive to tyrothricin . Some specific types of wounds are:
tyrothricin is a compound of different ring and straight polypeptides that have an effective antibacterial effect, formed by the endotoxicity of anaerobic cells of Bacillus Brevis bacteria. This compound contains up to 70 - 80% tyrocidins (basic ring decapeptides) and 20 - 30% gramicidin (central pentadecapeptide). The spectrum acts mainly on gram (+) bacteria, in addition to the effects on some gram (-) and fungi bacteria, including the Candida albicans.
tyrothricin has a bactericidal or antibacterial activity dependent on the following microorganisms:
Dosage has an inhibitory effect (µg/ml):
Staph. Aureus Mssa 4
Staph. Aureus MrSa 4
Staph. Haemolyticus 4
strep. Pyogenes 0.5
strep. Viridans 1 - 5
Enterococcus Faecalis 2
diplococcus pneumonia 1
corynebact spp. 2
Clostridia 0.1 - 10
candida albicans 16
Candida Parapsilosis 32
Dosage ≥ 50 micrograms/ml has the effect of inhibiting Neisseria meningitides, some species of neisseria gonorrhoeae, some mushrooms, trichomonas.
tyrocidin works by solving nitrogen and phosphate containing substances from bacterial cells. Similar to cation detergent, tyrocidin destroys the osmotic walls of bacterial cell membranes. This is the direct attack on the bacterial cell wall, which does not work on the growth or self -division of bacteria.
On the other hand, gramicidin forms a cation channel into the bacterial cell membrane, leading to a loss of potassium to create a change in intracellular cation concentration and eventually lead to cell cancellation. Gramicidin part also creates a phosphorylation of respiratory chain.Because of the special mechanism of tyrothricin, this mechanism is not found in other antibiotics, so the cross -resistance has not been seen.
In the treatment of wounds, Tyrosur Gel's effects are not only because of the outstanding microbiological activity but also by other characteristics that promote the treatment process. Clinical studies have shown that Tyrosur Gel promotes wound healing by cleaning the wound surface and stimulating the seed and epithelial coverage.
Dynamic pharmacokinetics
The tyrothricin process is absorbed into the body. High concentration is found in the horny layer (after absorbing through the skin healing) or directly at the wound.
Before taking Tyrosur Engelhard is treated and prevented with infections (5g)
How to use
Use topical.
Dosage
only use on the skin.
Normal dose: Apply the drug each time with sufficient amount, 2-3 times of bait.
Apply the drug in sufficient amount of skin that needs treatment in the morning, (noon) and evening. In case of small wounds or dermatitis on the open part of the body, usually no tape. In case of wide wound or watery water, should be tape, should change the bandage 1-2 times daily or according to the doctor's advice.
Duration of treatment depends on clinical manifestations. In case the disease has not improved after a week of medication, it is advisable to re -evaluate the treatment. The identification of pathogens should be performed.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
often have no consequences. Continue treatment with normal dose. However, if you see any abnormal symptoms when overdose, must consult a doctor.
What to do when you forget 1 dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.
Side Effects
When using Tyrosur Gel , you may experience unwanted effects (ADR).
Skin and subcutaneous tissue disorders: Very rare (ratio Instructions on how to handle ADR
When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
contraindicated
Tyrosur gel contraindicated in the following cases:
Be cautious when using
be careful when applying the drug near the eye area because it may have a burning sensation.
Tyrosur Gel contains propylene glycol that can cause skin irritation.
The ability to drive and operate machinery
No report.
Pregnancy
There is no evil on the safety of monkey drugs for pregnant women. There is not enough animal studies on tyrothricin's reproductive toxicity. Therefore, Tyrosur Gel should not be used for pregnant women.
Nursing period
It is unknown whether tyrothricin or cetylpyridinium chloride whether or not breast milk. Therefore, Tyrosur Gel should not be used for breastfeeding women.
Interactive drug
has not seen any drug interactions between Tyrosur Gel and other drugs.
Storage
Store drugs at room temperature.
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