Urostad 40 Stella treat acute pulmonary edema (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Furosemide

Ingredient

Composition information	Content
Furosemide	40mg

Uses

indications

Urostad 40 drugs are indicated in the following cases:

Acute pulmonary edema, heart, liver, kidney and other edema.

Hypertension when kidney damage.

Hypercalcemia.

Pharmacology

Furosemide is a diuretics of Sulfonamid diuretic belonging to a strong, fast, dosage -dependent effect group.

The drug acts on the upward branch of the Henle straps, so it is classified as a group of diuretics. Furosemide's beloved mastery is to inhibit the Na+, K+, 2Cl-2Cl transport system in the thick segment of the segment on the Henle straps, increasing the excretion of these electrolytes accompanied by increased water export exercises. There is also an increase in Ca ++ and Mg ++ elimination.

The diuretic effect of strong drugs, thus led to the effect of lowering blood pressure, but often weak. In patients with pulmonary edema, Furosemide causes increased venous volume, thus reducing the money burden for left ventricle before seeing the diuretic effect.

Dynamic pharmacokinetics

Furosemide absorb good through oral, diuretic effects appear quickly after 1 hour, reach a maximum concentration after 1-2 hours and maintain the effect from 4-6 hours. Anti -hypertension effect is longer. For people with severe edema, the bioavailability of the drug is reduced, possibly due to the direct effect of reducing the absorption of the gastrointestinal tract.

Furosemide's absorption may be extended and may be reduced by food. One third of the absorption drug is eliminated through the kidneys, the rest is eliminated through the urine, mainly in the form of non -metabolic, completely eliminated drugs for 24 hours.

Furosemide passes through the placenta fence and into breast milk.

Before taking Urostad 40 Stella treat acute pulmonary edema (5 blisters x 10 tablets)

How to use

Take oral use.

Dosage

edema: The oral dose started is usually 40 mg/day. Adjust the dose if necessary depending on the response. Mild cases may be used 20 mg/day or 40 mg daily. Some cases may increase the dose to 80 mg or further, divided into 1 or 2 times a day. In severe cases, the dose may be increased to 600 mg/day.

For children, the oral dosage is 1-3 mg/kg/day, up to 40 mg/day.

Hypertension: Furosemide is not the main medicine for treating hypertension and can be coordinated with other hypertension drugs to treat hypertension in people with kidney damage.

The oral dosage is 40 - 80 mg/day, solitary use or in combination with other antihypertensive drugs.

Hypercalcemia: 120 mg/day orally or divided into 2 or 3 small doses.

Elderly: may be more sensitive to the effect of the drug than the doses used in adults.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms:

Water and electrolyte imbalance include: headache, muscle weakness, cramps, thirst, hypotension, anorexia, fast pulse.

Treatment:

Compensate for the amount of water and electrolytes lost.

What to do when forgetting 1 dose? If you forget a dose, use it as soon as possible. However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Urostad 40, you may experience unwanted effects (ADR).

Unwanted effects mainly occur during high doses (accounting for 95% of harmful reactions). The most common is the electrolyte imbalance (596 patients who have been treated), which occurs mainly in patients with liver function and with patients with renal impairment during long -dose treatment. Some cases of light sensitivity have also been reported.

Common, ADR> 1/100

Circulation: Reducing blood volume in case of high therapy, hypotension.

Metabolic: Hypotension, hypoglycema, hypoxemia, blood calcium, hyperactical hyperactical acid, alkaline infection due to hypoglycemia.

Uncommon, 1/1000 ADR

Digestive: Nausea, vomiting, digestive disorders.

Rare, ADR

Blood: leukopenia, thrombocytopenia, loss of granulocytes.

skin: skin, vasculitis, paresthesia. metabolic: hyperlem of blood glucose, urinary glucose.

ears: tinnitus, recovery hearing (at high doses).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Urostad 40 contraindications in the following cases:

Hypersensitivity to Furosemide and with sulfonamid derivatives, such as diabetes sulfamid.

Money for liver, liver coma.

Animal or renal failure due to toxic drugs to the kidneys or liver.

Be cautious when using

Caution for patients with prostate hypertrophy or urination because it can promote urination.

Urostad 40 contains lactose excipients. This drug should not be used for patients with rare genetic problems galactose intolerance, deficit of total lactase enzyme or poor absorption of glucoze-galactose.

The ability to drive and operate machinery

Recommended patients with caution when driving, operating machinery and drugs that can cause antihypertensive posture, headache.

During pregnancy

Thiazid, thiazid diuretics and straps diuretics evenly through the fetus fence into the fetus and causing water disorders and electrolytes for the fetus. With thiazid and derivative, many cases of platelet reduction in newborns have been reported. This risk also appears after using straps diuretics such as Furosemide and Buretamid.

Therefore, in the last 3 months of pregnancy, the drug is only used when there is no alternative medicine, and only at the lowest dose in a short time.

The period of breastfeeding

using Furosemide during breastfeeding is at risk of inhibiting milk secretion. This case should stop breastfeeding.

Drug interaction

Modable interaction may occur when using Furoserride in combination with the following drugs:

cephalothin, cephaloridin: Increased kidney toxicity.

Lithi salt: Increased blood lithium concentration, can be toxic. Should avoid using if you cannot monitor the blood lithium tight.

Aminoglycozide: Increases toxicity for ears and kidneys. Should avoid use at the same time.

heart glycozide: increased toxicity due to hypoglycemia. Need to monitor blood potassium and electrocardiograms.

corticosteroid: Increasing k+.

Medications for diabetes treatment: The risk of increased blood glucose. Need to monitor and adjust the dose of diabetes treatment.

Non -reducing muscle relaxants: Increasing muscle relaxation effect.

Anticoagulants: Increasing anticoagulant effects.

cisplatin: Increased hearing toxicity. Should avoid use at the same time.

Anti -blood pressure medications: Increasing hypotension effect. If coordinated, dose adjustments.

Special when combined with Angiotensin enzyme inhibitors, blood pressure may be severely reduced.

Tyeum of drugs

Due to the absence of studies on the correlation of the drug, not mixing this drug with other drugs.

Storage

Store in closed packaging, dry place, avoid light. The temperature does not exceed 30 ° C.

Other drugs

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