Uruso tab. 100mg Daewoong Treatment of gallstones (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Ursodeoxycholic acid

Ingredient

Composition information	Content
Ursodeoxycholic acid	100mg

Uses

Indications

Uruso 100mg drug are indicated in the following cases:

Treatment gallstones rich in cholesterol when the gallbladder is still functional. Ursodeoxycholic acid reduces cholesterol saturation by inhibiting synthesis and excreting cholesterol in the liver, while inhibiting the reabsorption of cholesterol into the intestine. The effect of reducing cholesterol saturation allows slowly dissolving cholesterol.

In addition, ursodeoxycholic acid increases bile flow, which helps improve bile stasis. Ursodeoxycholic acid helps protect liver cells from toxic effects of liver toxicity of water -soluble bile acids (such as lithocholic acid, deoxycholic acid, chenodexolic acid) by inhibition of competitive absorption into the intestine.

pharmacokinetic pharmacokinetics

Distribution

After drinking, ursodeoxycholic acid into the bloodstream and is transferred directly to the liver, only a small amount of circulation within the circulation.

Metabolism

Ursodeoxycholic acid quickly absorbed into the liver and binds to glycine or taurine and then entered the bile. A small percentage of Ursodeoxycholic acid is subject to metabolism due to bacteria in the liver - intestinal cycle.

Elimination

Ursodeoxycholic acid is eliminated mainly in feces.

Before taking Uruso tab. 100mg Daewoong Treatment of gallstones (10 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

Adults and children over 12 years old

Cholesterol -rich gallstones when gallbladder is still functional

Use 8 - 12 mg/kg/day before sleeping or divided into 2-3 times (a larger dose than taken before going to bed). Time to use 6 - 24 months depending on the size of stones and stones.

Improve liver function in primary biliary cirrhosis

Use 10 - 15mg/kg/day divided into 2-4 times.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? In the case of diarrhea, water and electrolytes are required.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Uruso 100mg , you may experience unwanted effects (ADR).

Digestive: diarrhea , nausea, vomiting, rarely abdominal pain, constipation , heartburn, epigastric pain.

Hypersensitivity: itching, rarely rash.

Other ADR: body fatigue, dizziness.

Instructions on how to handle ADR

Notice to the doctor any adverse effects occur when taking this medication.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Uruso 100mg drug contraindicated in the following cases:

Patients with hypersensitivity to drugs or any ingredients of the drug.

Patients with complete bile duct clogged (bile effects can worsen symptoms).

Patients with hepatitis progresses rapidly.

Patients with calcium stones.

Patients with acute gallbladder inflammation.

Pregnant or suspected pregnant women.

Children under 12 years old.

Patients with kidney disease.

Patients with acute peptic ulcer.

Patients with colonitis or bowelitis like Crohn’s disease.

Be cautious when using

Precautions when indicating Uruso 100mg for the following patients:

Patients with severe pancreatic disease.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

Do not use this drug for pregnant women because they have reported fetal toxicity on test animals.

Breastfeeding period

It is not known whether this drug is excreted in breast milk or not. Because there are many excreted drugs on breast milk, be careful when prescribing this medication for nursing women.

Medicinal interaction

Be cautious when prescribing this drug along with the drug that lowered the blood tolbutamide for patients with diabetes due to this drug increasing the hypoglycemic effect of Tolbutamide.

The following drugs reduces the absorption capacity of ursodeoxycholic acid:

Cholestyramine, Colestipol, Activated carbon, drugs containing magnesi and aluminum hydroxyde.

Storage

Storage in closed packaging at temperatures below 30 ° C.

Other drugs

Disclaimer

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