Uruso tab. 200mg Daewoong Treatment of gallstones (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Ursodeoxycholic acid

Ingredient

Composition information	Content
Ursodeoxycholic acid	200mg

Uses

Indications

Uruso 200 mg drug are indicated in the following cases:

gallstones rich in cholesterol when the gallbladder is still functional. Storage in the gallbladder, ursodeoxycholic acid reduces cholesterol saturation by inhibiting synthesis and excreting cholesterol in the liver, while inhibiting the reabsorption of cholesterol into the intestine. The effect of reducing cholesterol saturation allows slowly dissolving cholesterol.

In addition, ursodeoxycholic acid increases bile flow, which helps improve bile stasis. Ursodeoxycholic acid helps protect liver cells from toxic effects of liver toxicity of water -soluble bile acids (such as lithocholic acid, deoxycholic acid, chenodexolic acid) by inhibition of competitive absorption into the intestine.

pharmacokinetic

Distribution:

After drinking, ursodeoxycholic acid into the bloodstream and is transferred directly to the liver, only a small amount of circulation within the circulation.

Metabolism:

Ursodeoxycholic acid quickly absorbed into the liver and binded to glycin or taurin and then entered the bile. A small percentage of Ursodeoxycholic acid is subject to metabolism due to bacteria in the liver - intestinal cycle.

Era:

Ursodeoxycholic acid is eliminated mainly in feces.

Before taking Uruso tab. 200mg Daewoong Treatment of gallstones (10 blisters x 10 tablets)

How to use

Oral drugs.

Dosage

This drug is only used as prescribed by a physician.

Adults and children over 12 years old

Cholesterol -rich gallstones when the gallbladder still functions: 8 - 12 mg/kg/day before sleeping or divided into 2-3 times (greater doses of taken before going to bed). Time to use 6 - 4 months depending on the size of the stones and the composition of stones.

Improve liver function in primary bile cirrhosis: 10 - 15 mg/kg/day divided into 2-4 times.

Improve liver function in hepatitis C: 12 - 18 mg/kg/day divided into 3 times.

Patients with liver failure

No dose adjustment for patients with liver failure.

Patients with renal failure

No dose adjustment for patients with renal failure.

Older people

There is no significant difference in the effectiveness of treatment and safety of ursodeoxycholic acid between the elderly and young people. However, due to the reduced physiological function in the elderly, cautious when using ursodeoxycholic acid for older patients.

Children

Safety and efficiency in children have not been established. Do not take this medicine for children under 12 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Overall, other symptoms of an overdose cannot occur due to ursodexolic acid absorption decreases when increasing the dose, and thus is waste heavily in feces.

There is no specific method in treating overdose. In the case of diarrhea, water and electrolytes are required.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Uruso 200 mg , you may experience unwanted effects (ADR).

digestive:

diarrhea , nausea, vomiting, rarely abdominal pain, constipation, heartburn, epigastric pain.

Itching, rarely rash.

Other adverse effects:

Body fatigue, dizziness.

Instructions on how to handle ADR:

When experiencing the side effects of the drug, it is necessary to notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Uruso 200 mg drug contraindicated in the following cases:

Patients who are hypersensitive to drugs or any ingredients of the drug.

Children under 12 years old.

Patients with renal disease.

Precautions when using

Precautions when indicating Uruso for the following patients:

Patients with severe pancreatic disease.

The ability to drive and operate machinery

The drug does not affect the ability to drive and operate machinery.

Pregnancy

Do not use this drug for pregnant women because they have reported fetal toxicity on test animals.

Breastfeeding period

It is not known whether this drug is excreted in breast milk or not. Because there are many excreted drugs on breast milk, be careful when prescribing this medication for nursing women.

Medicinal interaction

body weight when prescribed this drug, along with the drug that hypoglycemia tolbutamid for diabetics due to this drug increases the hypoglycemic effect of Tolbutamide.

The following drugs reduces the absorption capacity of ursodeoxycholic acid:

Cholestyramin, Colestipol, Activated Chon, drugs containing magnesi and aluminum hydroxyd.

Medications that increase cholesterol in bile (such as oral contraceptives containing estrogen) or drugs that reduce blood cholesterol (such as clofibrate).

Storage

Storage in closed packaging, temperature below 30⁰C.

Other drugs

Disclaimer

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