Usasartim 300mg Ampharco treatment of hypertension (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Irbesartan

Ingredient

Composition informationContent
Irbesartan300mg

Uses

indications

Usasartim 300 3x10 Ampharco is indicated in the following cases:

  • Treatment of high blood pressure: Can use monatlearization or in combination with other hypertension medications.

    • Kidney pathology in patients with diabetes Type 2: Treatment of diabetes with diabetes with hyperactive blood and protein urine in patients with hypertension and type 2 diabetes. Irbesartan helps reduce renal disease progression in these patients.

    Pharmacology

    Irbesartan is an Angiotensin II receptor receptor. Angiotensin II is a strong vascular contraction substance formed from angiotensin I in a reaction of the catalyzed angiotensin transferred enzymes. Irbesartan inhibits vascular shrinkage and aldosteron effects of Angiotensin II by attaching the AT1 receptors of Angiotensin II. Irbesartan does not inhibit angiotensin transfer enzymes, so the drug does not affect the metabolism of Bradykinin and therefore has little side effects.

    Dynamic pharmacology

    Irbesartan is absorbed quickly and completely by oral with an average bio -axioming of about 60 - 80%. The peak concentration of plasma is achieved after about 1.5-2 hours of taking the medicine. Food does not affect the availability of Irbesartan.

    The half -life of Irbesartan elimination is about 11-15 hours. The concentration of medication in the blood reaches a stable state after 3 days of taking the drug.

    Irbesartan is metabolized through associated with glucuronic acid and with oxidation. The main metabolic substance in the blood is the Irbesartan-glucuronic complex without pharmacological activity (about 6%).

    Irbesartan binds to serum protein at 90%. The average distribution volume is 53 - 93 liters. With repeated oral doses, Irbesartan does not show clinical medicine accumulation. Drugs through cerebral blood barriers and placenta are weak.

    Before taking Usasartim 300mg Ampharco treatment of hypertension (3 blisters x 10 tablets)

    How to use

    oral medication.

    Dosage

    High blood pressure

    The starting dose is 150 mg orally once daily. The dose can be increased to 300 mg once a day. A additional diuretics may be used as hydrochlorothiazid if you use a single Irbesartan that does not control blood pressure. No need dose for older patients or patients with liver failure, kidney failure.

    Kidney pathology caused by diabetes Type 2

    Maintenance dose of proposal 300 mg/day. There is no data on clinical effects when taking lower doses in patients with diabetic kidney disease. For patients who have a decrease in circulatory volume or hypoglycet hypoglycoc (such as strong diuretic treatment or dialysis) should start at a low dose of 75 mg a day.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose? Taking an overdose of Irbesartan can cause hypotension, tachycardia or slow. Cannot dialysis to discharge Irbesartan. Treatment is supportive treatment and symptoms.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using USasartim 300 3x10 Ampharco, you may experience unwanted effects (ADR).

  • Make side effects include abdominal pain, stress anxiety, tinnitus, edema, headache, muscle pain, sore throat, nausea, vomiting, skin rash, tachycardia ... The drug does not increase dry cough as often occurs with enamel inhibitors.

    • Instructions on how to handle ADR

    Notify the doctor with unwanted effects when using the drug.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Usasartim 300 3x10 Ampharco is contraindicated in the following cases:

  • Hypersensitivity to any ingredients of the drug.
  • Pregnant women.
  • Women who are breastfeeding.

    • Be cautious when used

    In patients with hypoglycemia such as salt loss and water due to strong diuretic group, diarrhea or prolonged vomiting, it is necessary to treat blood volume before Irbesartan.

    For people with kidney artery stenosis, when Irbesartan is used, there is a risk of severe hypotension and impaired renal function.

    Be careful with patients with kidney transplant or renal failure. Checking the concentration of potassium and blood creatinine is necessary.

    There may be hyperkalemia when using Irbesartan, especially patients with heart and kidney function. Should regularly check potassium potassium on these patients. Avoid simultaneous use of Irbesartan with diuretics keeping potassium.

    As well as other vasodilators, Irbesartan must be used carefully in diseases such as aortic valve stenosis and mitral valve stenosis, obstructive hypertrophic heart disease.

    Do not take medicine for children under 6 years old because there is little clinical data on this object.

    The ability to drive and operate machinery

    No report.

    Pregnancy

    No report.

    Breastfeeding period

    No report.

    Interactive drug

    Other anti -hypertension drugs may increase the hypotension effect of Irbesartan. However, Irbesartan can still be combined with other anti -hypertension drugs such as beta blockers, calcium channel blockers or thiazide diuretics. Simultaneous use of Irbesartan with diuretics holding potassium or potassium supplements may increase the concentration of potassium.

    There is no important pharmacological interaction when used with hydrochlorothiazid, digoxin, warfarin, and nifedipin. Irbesartan does not affect the dynamics of warfarin, hydrochlorothiazid and digoxin when using these drugs at daily maintenance dose.

    Storage

    Store at temperatures below 30 ° C. Avoid direct light and wet place.

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    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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