Utrogestan 100mg Besins medicine supplements hormones in gynecological disease (2 blisters x 15 tablets)

Dosage form Box of 2 blisters x 15 tablets
Specifications Progesterone

Ingredient

Composition information	Content
Progesterone	100mg

Uses

indications

Utrogestan 100mg drug are indicated in the following cases:

Oral

gynecological:

Disorders related to progesterone deficiency, such as Menstrual syndrome , irregular menstrual periods due to ovulation disorders or no ovulation, benign breast disease, premenopause.

threaten miscarriage or a consecutive miscarriage due to impairment.

infertility, primary or secondary infertility due to partial or completely royal failure (especially in ovulation disorders, supplementing the period of royal stages in vitro fertilization, egg donation). Contains fine -grained progesterone, oral and vaginal use significantly increases the level of plasma progesterone levels, so it will effectively add a deficiency of progesterone.

Dynamic pharmacokinetics

Progesterone concentration increases in the first hour and reaches the highest plasma peak concentration after 1 to 3 hours of use.

Metabolism:

Metabolic substances in plasma and urine are like substances secreted in the physical phase.

Before taking Utrogestan 100mg Besins medicine supplements hormones in gynecological disease (2 blisters x 15 tablets)

How to use and dose

Oral

The average dose is from 200 - 300mg of progesterone daily divided into 1-2 times, that is, use 200mg in the evening before going to bed and 100mg in the morning if needed.

In mental impairment (premenstrual syndrome, benign breast disease, irregular menstruation, premenopause):

Treatment for 10 days per cycle is usually from 17 to 26.

In replacement hormone therapy:

Simple estrogen therapy, progesterone is used in the last 2 weeks of the treatment, then stop all replacement treatment for about 1 week, during that time there may be bleeding when stopping the drug.

In premature birth:

400mg Progesterone every 6 - 8 hours depending on the clinical results at the acute phase, followed by the maintenance dose (3 x 200mg/day) to the 36th week of pregnancy.

Vaginal line

The average dose is 200mg of progesterone per day (1 tablet of 200mg or 2 tablets 100mg divided into 2 times, 1 tablet in the morning and 1 tablet in the evening), placed deep into the vagina. This dose may increase depending on the response of each patient.

In case of a partial deficiency (ovulation disorders, irregular menstruation):

200mg Progesterone per day, 10 days for each cycle, usually starting from 17 to day 26.

Infertility case due to a completely deficiency (oocyte donation):

The starting dose of 100mg Progesterone on the 13th and 14th of the embryo cycle, followed by 100mg of progesterone in the morning and evening from the 15th to the 25th day of the cycle. From the 26th day and in the case of pregnancy, increase the dose to 100mg/day per week to finally reach a maximum dose of 600mg/day divided into 3 times. Maintain this dose until the 60th day.

Supplementing the period of royal in vitro fertilization:

Start treatment at the evening of the embryo transfer at a dose of 600mg/day, divided into 3 times (morning, lunch and evening).

Threaten early miscarriage or consecutive miscarriage due to impairment:

200 - 400mg Progesterone daily divided into 2 times until the 12th week of pregnancy.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

with oral roads, unwanted effects recorded above are most overdose symptoms. In the case of reducing the dose, the symptoms will automatically go away. In some patients, the usual dose may be too high. The following tips for patients:

Dosage reduction or progesterone in the evening before going to bed, 10 days in a cycle in case of drowsiness or fleeting dizziness. Test to ensure enough oestradiol levels in the blood.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Utrogestan 100g , you may experience unwanted effects (ADR).

Common, ADR> 1/100

endocrine - genital: Change menstrual cycle, menstruation , bleeding between menstrual cycle.

Neurological: Sleep, fleeting dizziness.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Utrogestan 100mg drug contraindicated in the following cases:

Severe liver failure.

allergies or sensitivity to the active ingredient or any ingredient of the drug.

Be cautious when used

under the recommended conditions, this treatment is not contraception.

The menstrual cycle may be short or bleeding if the treatment starts too early, especially before the 15th of the cycle.

In the case of uterine bleeding, Utrogestan is not used until the cause is determined, such as by endometrial examination.

Due to the inability to completely eliminate the risk of blood switching and metabolism, it is advisable to stop treatment in the following cases:

Eye disorders such as vision loss, double vision, retinal vascular damage.

Should closely check in patients with a history of thrombosis.

In case of sudden menstruation, it must be certain that there is no pregnancy.

More than half of the cases of early spontaneous miscarriage due to genetic complications. Moreover, infections or mechanical disorders may have a miscarriage and premature birth. In these cases, progesterone only works to slow down dead eggs. Therefore, using progesterone should only be for cases where the royal secretion is not enough.

The ability to drive and operate machinery

Attention in the driver or using machines, this medicine can cause drowsiness and/or dizziness when used oral. To avoid this side effect should take the drug in the evening.

Pregnancy

There is no contraindication when using utrogestan during pregnancy even during the first weeks of pregnancy.

The period of breastfeeding

No specific research Progesterone has passed through breast milk or not, so avoid taking medicine for breastfeeding women.

Drug interaction

used in combination with other drugs can affect the metabolism of progesterone, which can change the effectiveness of the drug such as:

Strong enzyme induction drugs such as Barbiturate, anti -epileptic (phenytoin), Rifampicin, Phenylbutazon, Spironolacton and Griseofulvin: These drugs increase the metabolism in the liver. Steroid.

Progestin can reduce glucose absorption, so patients with diabetes will increase insulin demand and other diabetes treatments.

Storage

Store no more than 30 ° C.

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